Document Type : Review Article

Authors

1 Department of Physiology, Estahban School of Paramedical Sciences, School of Nursing Hazrat Zahra (P.B.U.H) Abadeh, Shiraz University of Medical Sciences, Shiraz, Iran

2 Department of Biology, Payam Noor University of Tehran, Tehran, Iran

3 Department of Chemical Engineering, Shiraz Branch, Islamic Azad University, Shiraz, Iran

4 Department of Nursing, School of Nursing Hazrat Zahra (P.B.U.H) Abadeh, Shiraz University of Medical Sciences, Shiraz, Iran

5 Department of Physiology, Iran University of Medical Sciences, Tehran, Iran

6 Department of Internal Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran

7 Department of Education, Abadeh Vesal High School, Abadeh, Iran

10.22038/ajp.2024.25131

Abstract

Objective: This scoping review aims to examine the potential health benefits of Anvillea garcinii and its compounds and provide recommendations based on available research. A. garcinii is a plant species in the daisy family that has demonstrated several therapeutic and preventive effects.
Materials and Methods: This review was conducted with a comprehensive approach. We meticulously searched multiple databases, including PubMed, Embase, Scopus, Cochrane, SID, and Magiran, using the keyword "A. garcinii " on October 4, 2023.
Results: Research suggests that A. garcinii extract possesses several properties that could benefit health. These include anti-hyperglycemic, anti-hyperlipidemic, and anti-inflammatory activities. The extract also displays anti-oxidant properties, enhances insulin sensitivity, and inhibits α-amylase and α-glucosidase. Additionally, it exhibits hepatoprotective activity, cytotoxic activity against cancerous cells, anti-fungal, anti-human immunodeficiency virus (HIV), anti-bacterial, anti-cholinesterase, and anti-tyrosinase activities.
Conclusion: The diverse health benefits of A. garcinii extract and its active compounds, such as germacranolide and parthenolide, present significant potential for use in the food, cosmetic, and pharmaceutical industries. This potential, especially in treating diabetes, gastric ulcers, and cancer, opens up exciting possibilities for the future.

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