Chen, Y. et al. Value of portal venous gas and a nomogram for predicting severe neonatal necrotizing enterocolitis. Pediatr. Res. https://doi.org/10.1038/s41390-024-03605-6 (2024).

Alsaied, A., Islam, N. & Thalib, L. Global incidence of necrotizing enterocolitis: a systematic review and meta-analysis. BMC Pediatr. 20, 344 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Sullivan, B. A. & Fairchild, K. D. Predictive monitoring for sepsis and necrotizing enterocolitis to prevent shock. Semin. Fetal Neonatal Med. 20, 255–261 (2015).

Article  PubMed  Google Scholar 

Hackam, D. J. & Sodhi, C. P. Bench to bedside—new insights into the pathogenesis of necrotizing enterocolitis. Nat. Rev. Gastroenterol. Hepatol. 19, 468–479 (2022).

Article  CAS  PubMed  Google Scholar 

Sodhi, C. P. et al. Intestinal epithelial toll-like receptor 4 regulates goblet cell development and is required for necrotizing enterocolitis in mice. Gastroenterology 143, 708–718.e705 (2012).

Article  CAS  PubMed  Google Scholar 

Werts, A. D. et al. A novel role for necroptosis in the pathogenesis of necrotizing Enterocolitis. Cell Mol. Gastroenterol. Hepatol. 9, 403–423 (2020).

Article  PubMed  Google Scholar 

Ladd, M. R., Nino, D. F., March, J. C., Sodhi, C. P. & Hackam, D. J. Generation of an artificial intestine for the management of short bowel syndrome. Curr. Opin. Organ Transpl. 21, 178–185 (2016).

Article  Google Scholar 

Sodhi, C. P. et al. The human milk oligosaccharides 2’-fucosyllactose and 6’-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling. Pediatr. Res. 89, 91–101 (2021).

Article  CAS  PubMed  Google Scholar 

Sodhi, C. P. et al. Fat composition in infant formula contributes to the severity of necrotising enterocolitis. Br. J. Nutr. 120, 665–680 (2018).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chi, C. et al. Effects of probiotics in preterm infants: a network meta-analysis. Pediatrics 147, e20200706 (2021). https://doi.org/10.1542/peds.2020-0706

Di, S. J., Wu, S. Y., Liu, T. J. & Shi, Y. Y. Stem cell therapy as a promising strategy in necrotizing enterocolitis. Mol. Med. 28, 107 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tong, L. & Chang, Y. T. Pneumatosis intestinalis in necrotizing enterocolitis. N. Engl. J. Med. 386, 1070 (2022).

Article  PubMed  Google Scholar 

Upadhyaya, V. D. et al. Is pneumoperitoneum an absolute indication for surgery in necrotizing enterocolitis? World J. Pediatr. 4, 41–44 (2008).

Article  PubMed  Google Scholar 

Wolfe, J. N. & Evans, W. A. Gas in the portal veins of the liver in infants; a roentgenographic demonstration with postmortem anatomical correlation. Am. J. Roentgenol. Radium Ther. Nucl. Med. 74, 486–488 (1955).

CAS  PubMed  Google Scholar 

Molik, K. A. et al. Portal venous air: the poor prognosis persists. J. Pediatr. Surg. 36, 1143–1145 (2001).

Article  CAS  PubMed  Google Scholar 

Ahle, M., Ringertz, H. G. & Rubesova, E. The role of imaging in the management of necrotising enterocolitis: a multispecialist survey and a review of the literature. Eur. Radiol. 28, 3621–3631 (2018).

Article  PubMed  PubMed Central  Google Scholar 

Sharma, R. et al. Portal venous gas and surgical outcome of neonatal necrotizing enterocolitis. J. Pediatr. Surg. 40, 371–376 (2005).

Article  PubMed  Google Scholar 

Chen, J. et al. Predictive factors for rapid progression in preterm neonates with necrotizing enterocolitis. Front Pediatr. 10, 970998 (2022).

Article  PubMed  Google Scholar 

Dordelmann, M. et al. Evaluation of portal venous gas detected by ultrasound examination for diagnosis of necrotising enterocolitis. Arch. Dis. Child Fetal Neonatal Ed. 94, F183–F187 (2009).

Article  CAS  PubMed  Google Scholar