Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street #07-01, Matrix, Singapore 138671, Republic of Singapore

School of Biological Sciences, Nanyang Technological University (NTU), 60 Nanyang Drive, 637551 Singapore, Republic of Singapore

Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, 117558 Singapore, Republic of Singapore