The Potential Role of Cannabidiol in Cosmetic Dermatology: A Literature Review

Lu HC, Mackie K. An introduction to the endogenous cannabinoid system. Biol Psychiatry. 2016;79:516–25.

Article  PubMed  CAS  Google Scholar 

Mechoulam R, Shvo Y. Hashish I. The structure of cannabidiol. Tetrahedron. 1963;19:2073–8.

Article  PubMed  CAS  Google Scholar 

Mechoulam R, Gaoni Y. A total synthesis of DL-delta-1-tetrahydrocannabinol, the active constituent of hashish. J Am Chem Soc. 1965;87:3273–5.

Article  PubMed  CAS  Google Scholar 

Mlost J, Bryk M, Starowicz K. Cannabidiol for pain treatment: focus on pharmacology and mechanism of action. Int J Mol Sci. 2020;21:8870.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Campos AC, Fogaça MV, Scarante FF, Joca SRL, Sales AJ, Gomes FV, et al. Plastic and neuroprotective mechanisms involved in the therapeutic effects of cannabidiol in psychiatric disorders. Front Pharmacol. 2017;8:269.

Article  PubMed  PubMed Central  Google Scholar 

Aziz AI, Nguyen LC, Oumeslakht L, Bensussan A, Ben MS. Cannabinoids as immune system modulators: cannabidiol potential therapeutic approaches and limitations. Cannabis Cannabinoid Res. 2023;8:254–69.

PubMed  CAS  Google Scholar 

Kuzumi A, Yamashita T, Fukasawa T, Yoshizaki-Ogawa A, Sato S, Yoshizaki A. Cannabinoids for the treatment of autoimmune and inflammatory skin diseases: a systematic review. Exp Dermatol. 2024;33: e15064.

Article  PubMed  CAS  Google Scholar 

Tóth K, Ádám D, Bíró T, Oláh A. Cannabinoid signaling in the skin: therapeutic potential of the “c(ut)annabinoid” system. Molecules. 2019;24:918.

Article  PubMed  PubMed Central  Google Scholar 

Shao K, Stewart C, Grant-Kels JM. Cannabis and the skin. Clin Dermatol. 2021;39:784–95.

Article  PubMed  Google Scholar 

Martinelli G, Magnavacca A, Fumagalli M, DellʼAgli M, Piazza S, Sangiovanni E. Cannabis sativa and skin health: dissecting the role of phytocannabinoids. Planta Med. 2022;88:492–506.

Article  PubMed  CAS  Google Scholar 

Palmieri B, Laurino C, Vadalà M. A therapeutic effect of CBD-enriched ointment in inflammatory skin diseases and cutaneous scars. Clin Ter. 2019;170:e93–9.

PubMed  CAS  Google Scholar 

Maghfour J, Rietcheck HR, Rundle CW, Runion TM, Jafri ZA, Dercon S, et al. An observational study of the application of a topical cannabinoid gel on sensitive dry skin. J Drugs Dermatol. 2020;19:1204–8.

Article  PubMed  Google Scholar 

Vincenzi C, Tosti A. Efficacy and tolerability of a shampoo containing broad-spectrum cannabidiol in the treatment of scalp inflammation in patients with mild to moderate scalp psoriasis or seborrheic dermatitis. Skin Appendage Disord. 2020;6:355–61.

Article  PubMed  PubMed Central  Google Scholar 

Chelliah MP, Zinn Z, Khuu P, Teng JMC. Self-initiated use of topical cannabidiol oil for epidermolysis bullosa. Pediatr Dermatol. 2018;35:e224–7.

Article  PubMed  Google Scholar 

Maida V, Corban J. Topical medical cannabis: a new treatment for wound pain: three cases of pyoderma gangrenosum. J Pain Symptom Manag. 2017;54:732–6.

Article  Google Scholar 

Jhawar N, Schoenberg E, Wang JV, Saedi N. The growing trend of cannabidiol in skincare products. Clin Dermatol. 2019;37:279–81.

Article  PubMed  Google Scholar 

Lim M, Kirchhof MG. Dermatology-related uses of medical cannabis promoted by dispensaries in Canada, Europe, and the United States. J Cutan Med Surg. 2019;23:178–84.

Article  PubMed  Google Scholar 

Matsuda LA, Lolait SJ, Brownstein MJ, Young AC, Bonner TI. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature. 1990;346:561–4.

Article  PubMed  CAS  Google Scholar 

Munro S, Thomas KL, Abu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature. 1993;365:61–5.

Article  PubMed  CAS  Google Scholar 

Baswan SM, Klosner AE, Glynn K, Rajgopal A, Malik K, Yim S, et al. Therapeutic potential of cannabidiol (CBD) for skin health and disorders. Clin Cosmet Investig Dermatol. 2020;13:927–42.

Article  PubMed  PubMed Central  CAS  Google Scholar 

De Petrocellis L, Di Marzo V. Non-CB1, non-CB2 receptors for endocannabinoids, plant cannabinoids, and synthetic cannabimimetics: focus on G-protein-coupled receptors and transient receptor potential channels. J Neuroimmune Pharmacol. 2010;5:103–21.

Article  PubMed  Google Scholar 

Pertwee RG, Howlett AC, Abood ME, Alexander SP, Di Marzo V, Elphick MR, et al. International union of basic and clinical pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CB₂. Pharmacol Rev. 2010;62:588–631.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Morales P, Reggio PH. An update on non-CB1, non-CB2 cannabinoid related G-protein-coupled receptors. Cannabis Cannabinoid Res. 2017;2:265–73.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Morales P, Hurst DP, Reggio PH. Molecular targets of the phytocannabinoids: a complex picture. Prog Chem Org Nat Prod. 2017;103:103–31.

PubMed  PubMed Central  CAS  Google Scholar 

Rio CD, Millan E, Garcia V, Appendino G, DeMesa J, Munoz E. The endocannabinoid system of the skin: a potential approach for the treatment of skin disorders. Biochem Pharmacol. 2018;157:122–33.

Article  PubMed  CAS  Google Scholar 

Devane WA, Hanus L, Breuer A, Pertwee RG, Stevenson LA, Griffin G, et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science. 1992;258:1946–9.

Article  PubMed  CAS  Google Scholar 

Sugiura T, Kondo S, Sukagawa A, Nakane S, Shinoda A, Itoh K, et al. 2-arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain. Biochem Biophys Res Commun. 1995;215:89–97.

Article  PubMed  CAS  Google Scholar 

Biro T, Toth BI, Hasko G, Paus R, Pacher P. The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities. Trends Pharmacol Sci. 2009;30:411–20.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Mackie K, Devane WA, Hille B. Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells. Mol Pharmacol. 1993;44:498–503.

PubMed  CAS  Google Scholar 

Sugiura T, Kodaka T, Nakane S, Miyashita T, Kondo S, Suhara Y, et al. Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor: structure-activity relationship of 2-arachidonoylglycerol, ether-linked analogues, and related compounds. J Biol Chem. 1999;274:2794–801.

Article  PubMed  CAS  Google Scholar 

Sugiura T, Kondo S, Kishimoto S, Miyashita T, Nakane S, Kodaka T, et al. Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor: comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells. J Biol Chem. 2000;275:605–12.

Article  PubMed  CAS  Google Scholar 

Lambert DM, DiPaolo FG, Sonveaux P, Kanyonyo M, Govaerts SJ, Hermans E, et al. Analogues and homologues of N-palmitoylethanolamide, a putative endogenous CB(2) cannabinoid, as potential ligands for the cannabinoid receptors. Biochim Biophys Acta. 1999;1440:266–74.

Article  PubMed  CAS 

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