https://edition.cnn.com/2024/04/18/health/heat-health-emergencies-record-high/index.html
Hsu A, Sheriff G, Chakraborty T, Manya D. Disproportionate exposure to urban heat island intensity across major US cities. Nat Commun. 2021;12(1):2721.
Article PubMed PubMed Central CAS Google Scholar
Tong S, Prior J, McGregor G, Shi X, Kinney P. Urban heat: an increasing threat to global health. BMJ. 2021;375: n2467.
Article PubMed PubMed Central Google Scholar
Iba T, Connors JM, Levi M, Levy JH. Heatstroke-induced coagulopathy: Biomarkers, mechanistic insights, and patient management. EClinicalMedicine. 2022;44: 101276.
Article PubMed PubMed Central Google Scholar
Wang Z, Zhu J, Zhang D, Lv J, Wu L, Liu Z. The significant mechanism and treatments of cell death in heatstroke. Apoptosis. 2024;29(7–8):967–80.
Article PubMed CAS Google Scholar
Paal P, Pasquier M, Darocha T, Lechner R, Kosinski S, Wallner B, Zafren K, Brugger H. Accidental hypothermia: 2021 update. Int J Environ Res Public Health. 2022;19(1):501.
Article PubMed PubMed Central Google Scholar
Jung KT, Bapat A, Kim YK, Hucker WJ, Lee K. Therapeutic hypothermia for acute myocardial infarction: a narrative review of evidence from animal and clinical studies. Korean J Anesthesiol. 2022;75(3):216–30.
Article PubMed PubMed Central CAS Google Scholar
Naučienė Z, Zūkienė R, Degutytė-Fomins L, Mildažienė V. Mitochondrial membrane barrier function as a target of hyperthermia. Medicina. 2012;48(5):249–55.
Wang Z, Cai F, Chen X, Luo M, Hu L, Lu Y. The role of mitochondria-derived reactive oxygen species in hyperthermia-induced platelet apoptosis. PLoS ONE. 2013;8(9): e75044.
Article PubMed PubMed Central CAS Google Scholar
Slimen IB, Najar T, Ghram A, Dabbebi H, Ben Mrad M, Abdrabbah M. Reactive oxygen species, heat stress and oxidative-induced mitochondrial damage. A review. Int J Hyperthermia. 2014;30(7):513–23.
White MG, Saleh O, Nonner D, Barrett EF, Moraes CT, Barrett JN. Mitochondrial dysfunction induced by heat stress in cultured rat CNS neurons. J Neurophysiol. 2012;108(8):2203–14.
Article PubMed PubMed Central CAS Google Scholar
Ferrer R, Iba T. Mitochondrial damage in sepsis. Juntendo Med J. 2024;70(4):269–72.
Yuen WF, Fung KP, Lee CY, Choy YM, Kong SK, Ko S, Kwok TT. Hyperthermia and tumour necrosis factor-alpha induced apoptosis via mitochondrial damage. Life Sci. 2000;67(6):725–32.
Article PubMed CAS Google Scholar
Eguchi Y, Shimizu S, Tsujimoto Y. Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res. 1997;57(10):1835–40.
Iba T, Helms J, Maier CL, Ferrer R, Levy JH. Mitochondrial dysfunction is a major cause of thromboinflammation and inflammatory cell death in critical illnesses. Inflamm Res. 2024 in press.
Iba T, Helms J, Maier CL, Ferrer R, Levy JH. Autophagy and autophagic cell death in sepsis: friend or foe? J Intensive Care. 2024;12(1):41.
Article PubMed PubMed Central Google Scholar
Dokladny K, Myers OB, Moseley PL. Heat shock response and autophagy–cooperation and control. Autophagy. 2015;11(2):200–13.
Article PubMed PubMed Central Google Scholar
Hu JM, Hsu CH, Lin YC, Kung CW, Chen SY, Lin WT, Cheng PY, Shen HH, Lee YM. Ethyl pyruvate ameliorates heat stroke-induced multiple organ dysfunction and inflammatory responses by induction of stress proteins and activation of autophagy in rats. Int J Hyperthermia. 2021;38(1):862–74.
Article PubMed CAS Google Scholar
Brownstein AJ, Ganesan S, Summers CM, Pearce S, Hale BJ, Ross JW, Gabler N, Seibert JT, Rhoads RP, Baumgard LH, Selsby JT. Heat stress causes dysfunctional autophagy in oxidative skeletal muscle. Physiol Rep. 2017;5(12): e13317.
Article PubMed PubMed Central Google Scholar
Katschinski DM, Wiedemann GJ, Longo W, d’Oleire FR, Spriggs D, Robins HI. Whole body hyperthermia cytokine induction: a review, and unifying hypothesis for myeloprotection in the setting of cytotoxic therapy. Cytokine Growth Factor Rev. 1999;10(2):93–7.
Article PubMed CAS Google Scholar
Ohara G, Okabe K, Toyama N, Ohta Y, Xinman S, Ichimura N, Sato K, Urata Y, Hibi H. Hyperthermia maintains death receptor expression and promotes TRAIL-induced apoptosis. J Oral Pathol Med. 2023;52(8):718–26.
Article PubMed CAS Google Scholar
Hall DM, Buettner GR, Oberley LW, Xu L, Matthes RD, Gisolfi CV. Mechanisms of circulatory and intestinal barrier dysfunction during whole body hyperthermia. Am J Physiol Heart Circ Physiol. 2001;280(2):H509–21.
Article PubMed CAS Google Scholar
Iba T, Sawada T, Kondo Y, Kondo K, Levy JH. Morphological changes in blood cells in a rat model of heatstroke: a pilot study. J Clin Med. 2022;11(16):4821.
Article PubMed PubMed Central CAS Google Scholar
Wang Z, Shi Q, Li S, Du J, Liu J, Dai K. Hyperthermia induces platelet apoptosis and glycoprotein Ibalpha ectodomain shedding. Platelets. 2010;21(3):229–37.
Laszlo A. The effects of hyperthermia on mammalian cell structure and function. Cell Prolif. 1992;25(2):59–87.
Article PubMed CAS Google Scholar
Coss RA, Linnemans WA. The effects of hyperthermia on the cytoskeleton: a review. Int J Hyperthermia. 1996;12(2):173–96.
Article PubMed CAS Google Scholar
Aroch I, Segev G, Loeb E, Bruchim Y. Peripheral nucleated red blood cells as a prognostic indicator in heatstroke in dogs. J Vet Intern Med. 2009;23(3):544–51.
Article PubMed CAS Google Scholar
Pawlik A, Nowak JM, Grzanka D, Gackowska L, Michalkiewicz J, Grzanka A. Hyperthermia induces cytoskeletal alterations and mitotic catastrophe in p53-deficient H1299 lung cancer cells. Acta Histochem. 2013;115(1):8–15.
Article PubMed CAS Google Scholar
Calderwood SK, Khaleque MA, Sawyer DB, Ciocca DR. Heat shock proteins in cancer: chaperones of tumorigenesis. Trends Biochem Sci. 2006;31(3):164–72.
Article PubMed CAS Google Scholar
Beere HM. “The stress of dying”: the role of heat shock proteins in the regulation of apoptosis. J Cell Sci. 2004;117(Pt 13):2641–51.
Article PubMed CAS Google Scholar
Bruchim Y, Segev G, Kelmer E, Codner C, Marisat A, Horowitz M. Hospitalized dogs recovery from naturally occurring heatstroke; does serum heat shock protein 72 can provide prognostic biomarker? Cell Stress Chaperones. 2016;21(1):123–30.
Article PubMed CAS Google Scholar
Iba T, Maier CL, Levi M, Levy JH. Thromboinflammation and microcirculation damage in heatstroke. Minerva Med. 2024;115(2):191–202.
Schlader ZJ, Davis MS, Bouchama A. Biomarkers of heatstroke-induced organ injury and repair. Exp Physiol. 2022;107(10):1159–71.
留言 (0)