Abraham R.T. 2001. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev. 15, 2177‒2196.
Article CAS PubMed Google Scholar
Paull T.T. 2015. Mechanisms of ATM activation. Annu. Rev. Biochem. 84, 711‒738.
Article CAS PubMed Google Scholar
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R., 3rd, Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N., Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J. 2007. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science. 316, 1160‒1166.
Article CAS PubMed Google Scholar
Shibata A., Jeggo P.A. 2021. ATM’s role in the repair of DNA double-strand breaks. Genes. 12 (9),1370.
Article CAS PubMed PubMed Central Google Scholar
Zhang X., Wan G., Berger F.G., He X., Lu X. 2011. The ATM kinase induces microRNA biogenesis in the DNA damage response. Mol. Cell. 41, 371‒383.
Article CAS PubMed PubMed Central Google Scholar
Liu J., Jin T., Ran L., Zhao Z., Zhu R., Xie G., Bi X. 2022. Profiling ATM regulated genes in Drosophila at physiological condition and after ionizing radiation. Hereditas. 159, 41.
Article CAS PubMed PubMed Central Google Scholar
Rothblum-Oviatt C., Wright J., Lefton-Greif M.A., McGrath-Morrow S.A., Crawford T.O., Lederman H.M. 2016. Ataxia telangiectasia: A review. Orphanet. J. Rare Dis. 11, 159.
Article PubMed PubMed Central Google Scholar
Chaudhary M.W., Al-Baradie R.S. 2014. Ataxia-telangiectasia: Future prospects. Appl. Clin. Genet. 7, 159–167.
PubMed PubMed Central Google Scholar
Barlow C., Hirotsune S., Paylor R., Liyanage M., Eckhaus M., Collins F., Shiloh Y., Crawley J.N., Ried T., Tagle D., Wynshaw-Boris A. 1996. Atm-deficient mice: A paradigm of ataxia telangiectasia. Cell. 86, 159‒171.
Article CAS PubMed Google Scholar
Quek H., Luff J., Cheung K., Kozlov S., Gatei M., Lee C.S., Bellingham M.C., Noakes P.G., Lim Y.C., Barnett N.L., Dingwall S., Wolvetang E., Mashimo T., Roberts T.L., Lavin M.F. 2017. A rat model of ataxia-telangiectasia: Evidence for a neurodegenerative phenotype. Hum. Mol. Genet. 26, 109‒123.
Chen K., Wang P., Chen J., Ying Y., Chen Y., Gilson E., Lu Y., Ye J. 2022. Loss of atm in zebrafish as a model of ataxia-telangiectasia syndrome. Biomedicines. 10 (2), 392.
Article CAS PubMed PubMed Central Google Scholar
Petersen A.J., Rimkus S.A., Wassarman D.A. 2012. ATM kinase inhibition in glial cells activates the innate immune response and causes neurodegeneration in Drosophila. Proc. Natl. Acad. Sci. U. S. A. 109, E656‒E664.
Article CAS PubMed PubMed Central Google Scholar
Petersen A.J., Katzenberger R.J., Wassarman D.A. 2013. The innate immune response transcription factor relish is necessary for neurodegeneration in a Drosophila model of ataxia-telangiectasia. Genetics. 194, 133‒142.
Article CAS PubMed PubMed Central Google Scholar
Silva E., Tiong S., Pedersen M., Homola E., Royou A., Fasulo B., Siriaco G., Campbell S.D. 2004. ATM is required for telomere maintenance and chromosome stability during Drosophila development. Curr. Biol. 14, 1341‒1347.
Article CAS PubMed Google Scholar
Chen T., Dong B., Lu Z., Tian B., Zhang J., Zhou J., Wu H., Zhang Y., Wu J., Lin P., Zhang J., Xu H., Mo X. 2010. A functional single nucleotide polymorphism in promoter of ATM is associated with longevity. Mech. Ageing Dev. 131, 636–640.
Article CAS PubMed Google Scholar
Piaceri I., Bagnoli S., Tedde A., Sorbi S., Nacmias B. 2013. Ataxia-telangiectasia mutated (ATM) genetic variant in Italian centenarians. Neurol. Sci. 34, 573–575.
Fu S., Hu J., Chen X., Li B., Shun H., Deng J., Zhang Y., Yao Y., Zhao Y. 2021. Mutant single nucleotide polymorphism rs189037 in ataxia-telangiectasia mutated gene is significantly associated with ventricular wall thickness and human lifespan. Front. Cardiovasc. Med. 8, 658908.
Article CAS PubMed PubMed Central Google Scholar
Ditch S., Paull T.T. 2012. The ATM protein kinase and cellular redox signaling: Beyond the DNA damage response. Trends Biochem. Sci. 37, 15‒22.
Article CAS PubMed Google Scholar
Amirifar P., Ranjouri M.R., Yazdani R., Abolhassani H., Aghamohammadi A. 2019. Ataxia-telangiectasia: A review of clinical features and molecular pathology. Pediatr. Allergy Immunol. 30, 277‒288.
Valentin-Vega Y.A., Maclean K.H., Tait-Mulder J., Milasta S., Steeves M., Dorsey F.C., Cleveland J.L., Green D.R., Kastan M.B. 2012. Mitochondrial dysfunction in ataxia-telangiectasia. Blood. 119, 1490‒1500.
Article CAS PubMed PubMed Central Google Scholar
Hirozane T., Tohmonda T., Yoda M., Shimoda M., Kanai Y., Matsumoto M., Morioka H., Nakamura M., Horiuchi K. 2016. Conditional abrogation of Atm in osteoclasts extends osteoclast lifespan and results in reduced bone mass. Sci. Rep. 6, 34426.
Article CAS PubMed PubMed Central Google Scholar
Weitering T.J., Takada S., Weemaes C.M.R., van Schouwenburg P.A., van der Burg M. 2021. ATM: Translating the DNA damage response to adaptive immunity. Trends Immunol. 42, 350‒365.
Article CAS PubMed Google Scholar
Stagni V., Cirotti C., Barilà D. 2018. Ataxia-telangiectasia mutated kinase in the control of oxidative stress, mitochondria, and autophagy in cancer: A maestro with a large orchestra. Front. Oncol. 8, 73.
Article PubMed PubMed Central Google Scholar
Stagni V., Ferri A., Cirotti C., Barilà D. 2020. ATM kinase-dependent regulation of autophagy: A key player in senescence? Front. Cell Dev. Biol. 8, 599048.
Osorio F.G., Barcena C., Soria-Valles C., Ramsay A.J., de Carlos F., Cobo J., Fueyo A., Freije J.M., Lopez-Otin C. 2012. Nuclear lamina defects cause ATM-dependent NF-kappaB activation and link accelerated aging to a systemic inflammatory response. Genes Dev. 26, 2311–2324.
Article CAS PubMed PubMed Central Google Scholar
Lee S.S., Bohrson C., Pike A.M., Wheelan S.J., Greider C.W. 2015. ATM kinase is required for telomere elongation in mouse and human cells. Cell Rep. 13, 1623‒1632.
Article CAS PubMed PubMed Central Google Scholar
Kang H.T., Park J.T., Choi K., Kim Y., Choi H.J.C., Jung C.W., Lee Y.S., Park S.C. 2017. Chemical screening identifies ATM as a target for alleviating senescence. Nat. Chem. Biol. 13, 616–623.
Article CAS PubMed Google Scholar
Kuk M.U., Kim J.W., Lee Y.S., Cho K.A., Park J.T., Park S.C. 2019. Alleviation of senescence via ATM inhibition in accelerated aging models. Mol. Cells. 42, 210–217.
CAS PubMed PubMed Central Google Scholar
Hari K.L., Santerre A., Sekelsky J.J., McKim K.S., Boyd J.B., Hawley R.S. 1995. The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene. Cell. 82, 815–821.
留言 (0)