Jiang S., Guo Y. 2020. Epigenetic clock: DNA methylation in aging. Stem Cells Int. 2020, 1047896.

Article  PubMed  PubMed Central  Google Scholar 

Perez-Gomez A., Buxbaum J.N., Petrascheck M. 2020. The aging transcriptome: read between the lines. Curr. Opin. Neurobiol. 63, 170–175.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Takasugi M., Yoshida, Y., Nonaka Y., Ohtani N. 2023. Gene expressions associated with longer lifespan and aging exhibit similarity in mammals. Nucl. Acids Res. 51 (14), 7205–7219.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen L., Ganz P.A., Sehl M.E. 2022. DNA methylation, aging, and cancer risk: A mini-review. Front. Bioinform. 2, 847629.

Article  PubMed  PubMed Central  Google Scholar 

Johnson A.A., Akman K., Calimport S.R., Wuttke D., Stolzing A., de Magalhães J.P. 2012. The role of DNA methylation in aging, rejuvenation, and age-related disease. Rejuvenation Res. 15 (5), 483–494.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Keenan C.R., Allan R.S. 2019. Epigenomic drivers of immune dysfunction in aging. Aging Cell. 18 (1), e12878.

Article  CAS  PubMed  Google Scholar 

Einarsson H., Salvatore M., Vaagensø C., Alcaraz N., Bornholdt J., Rennie S., Andersson R. 2022. Promoter sequence and architecture determine expression variability and confer robustness to genetic variants. eLife. 11, e80943.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kreamer N.N., Phillips R., Newman D.K., Boedicker J.Q. 2015. Predicting the impact of promoter variability on regulatory outputs. Sci. Rep. 5, 18238.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nojimaa S., Fuchikamia M., Kataokaa T., Arakia M., Omuraa J., Miyagia T., Okamotoa Y., Hishimotob A., Morinobu S. 2021. Alterations in DNA methylation rates of brain-derived neurotrophic factor in patients with schizophrenia. Eur. J. Psychiatry. 35 (2), 67‒74.

Article  Google Scholar 

de Mendoza A., Nguyen T.V., Ford E., Poppe D., Buckberry S., Pflueger J., Grimmer M.R., Stol-zenburg S., Bogdanovic O., Oshlack A., Farnham P.J., Blancafort P., Lister R. 2022. Large-scale manipulation of promoter DNA methylation reveals context-specific transcriptional responses and stability. Genome Biol. 23 (1), 163.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vavouri T., Lehner B. 2012. Human genes with CpG island promoters have a distinct transcription-associated chromatin organization. Genome Biol. 13 (11), R110.

Article  PubMed  PubMed Central  Google Scholar 

Nam A.R., Lee K.H., Hwang H.J., Schabort J.J., An J.H., Won S.H., Cho J.Y. 2020. Alternative methylation of intron motifs is associated with cancer-related gene expression in both canine mammary tumor and human breast cancer. Clin. Epigenetics. 12 (1), 110.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang X., Wu M., Xiao H., Lee M.T., Levin L., Leung Y. K., Ho S.M. 2010. Methylation of a single intronic CpG mediates expression silencing of the PMP24 gene in prostate cancer. Prostate. 70 (7), 765–776.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hong J., Je-Keun R. 2022. Genomic effect of DNA methylation on gene expression in colorectal cancer. Biology. 11 (10), 1388.

Article  PubMed  PubMed Central  Google Scholar 

Walker K.A., Basisty N., Wilson D.M., 3rd, Ferrucci L. 2022. Connecting aging biology and inflammation in the omics era. J. Clin. Invest. 132 (14), e158448.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li X., Li C., Zhang W., Wang Y., Qian P., Huang H. 2023. Inflammation and aging: Signaling pathways and intervention therapies. Signal Transduct. Target. Ther. 8 (1), 239.

Article  PubMed  PubMed Central  Google Scholar 

Yusipov I., Kondakova E., Kalyakulina A., Krivonosov M., Lobanova N., Bacalini M.G., Franceschi C., Vedunova M., Ivanchenko M. 2022. Accelerated epigenetic aging and inflammatory/immunological profile (ipAGE) in patients with chronic kidney disease. GeroSci. 44 (2), 817–834.

Article  CAS  Google Scholar 

Wing M.R., Devaney J.M., Joffe M.M., Xie D., Feldman H.I., Dominic E.A., Guzman N.J., Ramezani A., Susztak K., Herman J.G., Cope L., Harmon B., Kwabi-Addo B., Gordish-Dressman H., Go A.S., He J., Lash J.P., Kusek J.W., Raj D.S., Chronic Renal Insufficiency Cohort (CRIC) Study. 2014. DNA methylation profile associated with rapid decline in kidney function: Findings from the CRIC study. Nephrol. Dial. Transplant. 29 (4), 864–872.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Maldonado M.D.M., Schlom J., Hamilton D.H. 2023. Blockade of tumor-derived colony-stimulating factor 1 (CSF1) promotes an immune-permissive tumor microenvironment. Cancer Immunol. Immunother. 72 (10), 3349‒3362.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ambrosi T.H., Marecic O., McArdle A., Sinha R., Gulati G.S., Tong X., Wang Y., Steininger H.M., Hoover M.Y., Koepke L.S., Murphy M.P., Sokol J., Seo E.Y., Tevlin R., Lopez M., Brewer R.E., Mascharak S., Lu L., Ajanaku O., Conley S.D., Seita J., Morri M., Neff N.F., Sahoo D., Yang F., Weissman I.L., Longaker M.T., Chan C.K.F. 2021. Aged skeletal stem cells generate an inflammatory degenerative niche. Nature. 597 (7875), 256‒262. https://doi.org/10.1038/s41586-021-03795-7

Article  CAS  PubMed  PubMed Central  Google Scholar 

Plotkin L.I., Bivi N. 2014. Chapter 3: Local regulation of bone cell function. In: Basic and Applied Bone Biology. Eds Burr D.B., Allen M.R. San Diego: Acad. Press, pp. 47–73.

Menke J., Iwata Y., Rabacal W.A., Basu R., Stanley E.R., Kelley V.R. 2011. Distinct roles of CSF-1 isoforms in lupus nephritis. J. Am. Soc. Nephrol. 22 (10), 1821–1833.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cain J.A., Montibus B., Oakey R.J. 2022. Intragenic CpG Islands and their impact on gene regulation. Front. Cell Dev. Biol. 10, 832348.

Article  PubMed  PubMed Central  Google Scholar 

Ogushi S., Yoshida Y., Nakanishi T., Kimura, T. 2020. CpG site-specific regulation of metallothionein-1 gene expression. Int. J. Mol. Sci. 21 (17), 5946.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Piber D., Olmstead R., Cho J.H., Witarama T., Perez C., Dietz N., Seeman T.E., Breen E.C., Cole S.W., Irwin M.R. 2019. Inflammaging: Age and systemic, cellular, and nuclear inflammatory biology in older adults. J. Gerontol. Ser. A, Biol. Sci. Med. Sci. 74 (11), 1716–1724.

Article  CAS  Google Scholar 

O’Brien J., Hayder H., Zayed Y., Peng C. 2018. Overview of microRNA biogenesis, mechanisms of actions, and circulation. Front. Endocrinol. 9, 402.

Article  Google Scholar 

Zhou, W.Y., Cai Z.R., Liu J., Wang D.S., Ju H. Q., Xu R.H. 2020. Circular RNA: metabolism, functions and interactions with proteins. Mol. Cancer. 19 (1), 172.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dong X., Weng Z. 2013. The correlation between histone modifications and gene expression. Epigenomics. 5 (2), 113–116.

Article  CAS  PubMed  Google Scholar 

Kaikkonen M.U., Lam M.T., Glass C.K. 2011. Non-coding RNAs as regulators of gene expression and epigenetics. Cardiovascular Res. 90 (3), 430–440.

Article  CAS  Google Scholar 

Liu R., Liu H., Chen X., Kirby M., Brown P.O., Zhao K. 2001. Regulation of CSF1 promoter by the SWI/SNF-like BAF complex. Cell. 106 (3), 309–318.

Article  CAS