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Retrieval of CTNNB1 CDS and multiple sequence alignment
Prediction of siRNAs
GC content, presence of palindromic sequences, and off-target similarity search
Prediction of target site accessibility
Secondary structure prediction of siRNA and mRNA-siRNA duplexes and thermodynamics analysis
Structure retrieval and optimization of human Argonaute 2
siRNA tertiary structure modeling
Molecular docking of siRNAs to human Argonaute 2
Molecular dynamics of the siRNA-Ago2 complex
Binding energy calculation
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