Material

Method

Data analysis and desirability function

Preparation of Candesartan cilexe­til-loaded nanosuspension

Determination of melting point

Determination of the maximum λmax of candesartan cilexetil

Construction calibration curves of candesartan cilexetil

Saturated solubility of candesartan cilexetil

Particle size and polydispersity index analysis

Determination of entrapment efficiency (EE%) of candesartan cilexetil

Development and evaluation of the optimised formulation

Freeze drying of nanosuspension

Morphological studies using AFM analy­sis

Compatibility analysis using DSC analysis

Drug-excipient compatibility studies using FTIR

In vitro release study

Stability study

Statistical analysis