Synthesis and biological activity evaluation of new isatin-gallate hybrids as antioxidant and anticancer agents (in vitro) and in silico study as anticancer agents and coronavirus inhibitors
Synthesis of 3,4,5-trihydroxybenzohydrazide (compound 1)
General procedure for preparation of the target hybrids (3a–d)
3,4,5-Trihydroxy-N’-(2-oxoindolin-3-ylidene)benzohydrazide (3a)
3,4,5-trihydroxy-N’-(5-methoxy-2-oxoindolin-3-ylidene) benzohydrazide(3b)
N’-(5-Bromo-2-oxoindolin-3-ylidene)-3,4,5-trihydroxybenzohydrazide(3c)
N’-(5-fluoro-2-oxoindolin-3-ylidene)-3,4,5-trihydroxybenzohydrazide(3d)
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