Nanostructured lipid carriers: A prospective dermal drug delivery system for natural active ingredients

Article title

Abstract

Keywords

Introduction

Dermal delivery system for natural active ingredient

Nanostructured Lipid Carriers (NLCs)

Advantages and limitations

Different types of NLCs

Lipids

Phospholipids

Fatty acids

Wax esters

Triglycerides

Cationic lipids

Ionizable lipids

Surfactants

NLC Preparation methods

High-pressure homogenization (HPH)

High-shear homogenization (HSH) and ultrasonication

Microemulsion

Solvent emulsification/evaporation

Membrane contactors

Phase inversion temperature (PIT)

Coacervation

NLC Characterization

Recent developments in the use of NLCs for natural active ingredient delivery

NLCs increase the effectivity and bioactivity of natural active ingredients

NLCs increase the stability of natural active ingredients

NLCs control drug release and deliver natural active ingredients with different polarity

Conclusion

References

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