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Proto-Oncogene Proteins c-mdm2
An E3 UBIQUITIN LIGASE that interacts with and inhibits TUMOR SUPPRESSOR PROTEIN P53. Its ability to ubiquitinate p53 is regulated by TUMOR SUPPRESSOR PROTEIN P14ARF.
推出的年份: 2006(1991)
副标题
administration and dosage
adverse effects
analysis
antagonists and inhibitors
biosynthesis
blood
cerebrospinal fluid
chemical synthesis
chemistry
classification
deficiency
drug effects
economics
genetics
history
immunology
isolation and purification
metabolism
pharmacokinetics
pharmacology
physiology
poisoning
radiation effects
standards
supply and distribution
therapeutic use
toxicity
ultrastructure
urine
树号:
D08.811.464.938.750.562, D12.776.624.664.700.185, D12.776.660.764
MeSH 单一 ID:
D051736
进入的组:
Proto Oncogene Proteins c mdm2
c-mdm2, Proto-Oncogene Proteins
Mdm2 Protein
Double Minute 2 Protein
c-mdm2 Proto-Oncogene Protein
Proto-Oncogene Protein, c-mdm2
c mdm2 Proto Oncogene Protein
Murine Double Minute 2 Protein
Mdm-2 Protein
Mdm 2 Protein
MDMX Protein
All MeSH Categories
Chemicals and Drugs Category
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Ligases [D08.811.464]
Ubiquitin-Protein Ligase Complexes [D08.811.464.938]
Ubiquitin-Protein Ligases [D08.811.464.938.750]
Anaphase-Promoting Complex-Cyclosome [D08.811.464.938.750.092]
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Fanconi Anemia Complementation Group L Protein [D08.811.464.938.750.186]
Inhibitor of Apoptosis Proteins [D08.811.464.938.750.210]
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Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein [D08.811.464.938.750.233]
Nedd4 Ubiquitin Protein Ligases [D08.811.464.938.750.257]
Polycomb Repressive Complex 1 [D08.811.464.938.750.280]
Proto-Oncogene Proteins c-cbl [D08.811.464.938.750.374]
Proto-Oncogene Proteins c-mdm2 [D08.811.464.938.750.562]
Receptors, Autocrine Motility Factor [D08.811.464.938.750.656]
SKP Cullin F-Box Protein Ligases [D08.811.464.938.750.750]
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Tripartite Motif-Containing Protein 28 [D08.811.464.938.750.782]
Tumor Necrosis Factor alpha-Induced Protein 3 [D08.811.464.938.750.813]
Von Hippel-Lindau Tumor Suppressor Protein [D08.811.464.938.750.875]
All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Neoplasm Proteins [D12.776.624]
Oncogene Proteins [D12.776.624.664]
Proto-Oncogene Proteins [D12.776.624.664.700]
B-Cell Lymphoma 3 Protein [D12.776.624.664.700.165]
Bcl-2-Like Protein 11 [D12.776.624.664.700.025]
c-Mer Tyrosine Kinase [D12.776.624.664.700.037]
Chemokine CXCL1 [D12.776.624.664.700.049]
Cyclin D1 [D12.776.624.664.700.100]
Fibroblast Growth Factor 4 [D12.776.624.664.700.110]
Fibroblast Growth Factor 6 [D12.776.624.664.700.112]
fms-Like Tyrosine Kinase 3 [D12.776.624.664.700.114]
Janus Kinase 2 [D12.776.624.664.700.117]
KRIT1 Protein [D12.776.624.664.700.119]
Kruppel-Like Factor 6 [D12.776.624.664.700.120]
Lipocalin-2 [D12.776.624.664.700.123]
Lymphocyte Specific Protein Tyrosine Kinase p56(lck) [D12.776.624.664.700.128]
MDS1 and EVI1 Complex Locus Protein [D12.776.624.664.700.129]
MutS Homolog 2 Protein [D12.776.624.664.700.130]
Myeloid-Lymphoid Leukemia Protein [D12.776.624.664.700.148]
N-Myc Proto-Oncogene Protein [D12.776.624.664.700.158]
Pre-B-Cell Leukemia Transcription Factor 1 [D12.776.624.664.700.163]
Proto-Oncogene Mas [D12.776.624.664.700.166]
Proto-Oncogene Proteins c-abl [D12.776.624.664.700.167]
Proto-Oncogene Proteins c-akt [D12.776.624.664.700.168]
Proto-Oncogene Proteins c-bcl-2 [D12.776.624.664.700.169]
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Proto-Oncogene Proteins c-bcl-6 [D12.776.624.664.700.170]
Proto-Oncogene Proteins c-bcr [D12.776.624.664.700.171]
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Proto-Oncogene Proteins c-cbl [D12.776.624.664.700.172]
Proto-Oncogene Proteins c-crk [D12.776.624.664.700.174]
Proto-Oncogene Proteins c-ets [D12.776.624.664.700.175]
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Proto-Oncogene Proteins c-fes [D12.776.624.664.700.177]
Proto-Oncogene Proteins c-fos [D12.776.624.664.700.179]
Proto-Oncogene Proteins c-fyn [D12.776.624.664.700.180]
Proto-Oncogene Proteins c-hck [D12.776.624.664.700.181]
Proto-Oncogene Proteins c-jun [D12.776.624.664.700.182]
Proto-Oncogene Proteins c-kit [D12.776.624.664.700.183]
Proto-Oncogene Proteins c-maf [D12.776.624.664.700.184]
Proto-Oncogene Proteins c-mdm2 [D12.776.624.664.700.185]
Proto-Oncogene Proteins c-met [D12.776.624.664.700.186]
Proto-Oncogene Proteins c-mos [D12.776.624.664.700.187]
Proto-Oncogene Proteins c-myb [D12.776.624.664.700.188]
Proto-Oncogene Proteins c-myc [D12.776.624.664.700.189]
Proto-Oncogene Proteins c-pim-1 [D12.776.624.664.700.191]
Proto-Oncogene Proteins c-rel [D12.776.624.664.700.192]
Proto-Oncogene Proteins c-ret [D12.776.624.664.700.194]
Proto-Oncogene Proteins c-sis [D12.776.624.664.700.195]
Proto-Oncogene Proteins c-vav [D12.776.624.664.700.198]
Proto-Oncogene Proteins c-yes [D12.776.624.664.700.199]
Proto-Oncogene Proteins p21(ras) [D12.776.624.664.700.200]
Proto-Oncogene Proteins pp60(c-src) [D12.776.624.664.700.202]
raf Kinases [D12.776.624.664.700.204]
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Receptor, ErbB-2 [D12.776.624.664.700.642]
Receptor, ErbB-3 [D12.776.624.664.700.790]
Receptor, ErbB-4 [D12.776.624.664.700.791]
Receptor, Fibroblast Growth Factor, Type 3 [D12.776.624.664.700.792]
Receptor, Macrophage Colony-Stimulating Factor [D12.776.624.664.700.800]
Receptor, Notch4 [D12.776.624.664.700.815]
Receptors, Thyroid Hormone [D12.776.624.664.700.830]
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RNA-Binding Protein EWS [D12.776.624.664.700.913]
RNA-Binding Protein FUS [D12.776.624.664.700.915]
RUNX1 Translocation Partner 1 Protein [D12.776.624.664.700.936]
Stathmin [D12.776.624.664.700.957]
T-Cell Acute Lymphocytic Leukemia Protein 1 [D12.776.624.664.700.960]
Wnt-5a Protein [D12.776.624.664.700.962]
Wnt1 Protein [D12.776.624.664.700.967]
Wnt2 Protein [D12.776.624.664.700.978]
Zinc Finger Protein GLI1 [D12.776.624.664.700.989]
All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Nuclear Proteins [D12.776.660]
Antennapedia Homeodomain Protein [D12.776.660.049]
Antigens, Nuclear [D12.776.660.625]
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Ataxins [D12.776.660.075]
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BRCA1 Protein [D12.776.660.100]
BRCA2 Protein [D12.776.660.105]
CCAAT-Enhancer-Binding Proteins [D12.776.660.167]
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CDX2 Transcription Factor [D12.776.660.201]
Chromosomal Proteins, Non-Histone [D12.776.660.235]
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Fanconi Anemia Complementation Group A Protein [D12.776.660.264]
Fanconi Anemia Complementation Group D2 Protein [D12.776.660.285]
Fanconi Anemia Complementation Group E Protein [D12.776.660.289]
Fanconi Anemia Complementation Group F Protein [D12.776.660.293]
Fanconi Anemia Complementation Group N Protein [D12.776.660.323]
Hepatocyte Nuclear Factors [D12.776.660.352]
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Homeobox Protein Nkx-2.2 [D12.776.660.415]
Host Cell Factor C1 [D12.776.660.478]
Immunoglobulin J Recombination Signal Sequence-Binding Protein [D12.776.660.486]
Inhibitor of Growth Protein 1 [D12.776.660.494]
Karyopherins [D12.776.660.502]
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Mad2 Proteins [D12.776.660.526]
Mediator Complex [D12.776.660.551]
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NF-kappa B [D12.776.660.600]
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Nuclear Matrix-Associated Proteins [D12.776.660.650]
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Nuclear Receptor Coactivators [D12.776.660.675]
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Nuclear Receptor Interacting Protein 1 [D12.776.660.688]
Nucleophosmin [D12.776.660.694]
Oncogene Protein p55(v-myc) [D12.776.660.700]
Poly-ADP-Ribose Binding Proteins [D12.776.660.720]
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Proliferating Cell Nuclear Antigen [D12.776.660.740]
Promyelocytic Leukemia Protein [D12.776.660.745]
Protamines [D12.776.660.750]
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Proto-Oncogene Proteins c-fos [D12.776.660.760]
Proto-Oncogene Proteins c-jun [D12.776.660.763]
Proto-Oncogene Proteins c-mdm2 [D12.776.660.764]
Proto-Oncogene Proteins c-myc [D12.776.660.765]
Proto-Oncogene Proteins c-rel [D12.776.660.767]
ran GTP-Binding Protein [D12.776.660.768]
Retinoblastoma Binding Proteins [D12.776.660.769]
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Retinoblastoma Protein [D12.776.660.807]
Retinoblastoma-Like Protein p107 [D12.776.660.770]
Retinoblastoma-Like Protein p130 [D12.776.660.794]
Silent Information Regulator Proteins, Saccharomyces cerevisiae [D12.776.660.820]
Thyroid Nuclear Factor 1 [D12.776.660.823]
Tumor Protein p73 [D12.776.660.912]
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