Silent Information Regulator Proteins, Saccharomyces cerevisiae
A set of nuclear proteins in SACCHAROMYCES CEREVISIAE that are required for the transcriptional repression of the silent mating type loci. They mediate the formation of silenced CHROMATIN and repress both transcription and recombination at other loci as well. They are comprised of 4 non-homologous, interacting proteins, Sir1p, Sir2p, Sir3p, and Sir4p. Sir2p, an NAD-dependent HISTONE DEACETYLASE, is the founding member of the family of SIRTUINS.
推出的年份: 2003
副标题
树号: D12.776.354.750.750, D12.776.660.820
MeSH 单一 ID: D038281
进入的组:
Silent Information Regulator Proteins, S cerevisiae
SIR Proteins, S cerevisiae
Silent Mating Type Information Regulator Protein, S cerevisiae
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