Proto-Oncogene Proteins c-kit

A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEINS C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis.

推出的年份: 2000(1996)

树号: D08.811.913.696.620.682.725.400.050, D12.776.476.568.400.050, D12.776.543.750.630.124, D12.776.543.750.705.852.150.100, D12.776.543.750.750.400.200.170, D12.776.624.664.700.183

MeSH 单一 ID: D019009

进入的组:

Proto Oncogene Proteins c kit
c-kit, Proto-Oncogene Proteins
Stem Cell Factor Receptor
SCF Receptor
p145 c-kit
c-kit, p145
p145 c kit
p145(c-kit)
p145c-kit
p145c kit
CD117 Antigen
Antigens, CD117
CD117 Antigens
Proto-Oncogene Protein c-kit
Proto Oncogene Protein c kit
c-kit, Proto-Oncogene Protein
c-kit Protein
c kit Protein
kit Proto-Oncogene Protein
Proto-Oncogene Protein, kit
kit Proto Oncogene Protein
Receptor, Stem Cell Factor
Proto-Oncogene Protein kit
Proto Oncogene Protein kit
c-kit Receptor
c kit Receptor

早前的内容:

Proto-Oncogene Proteins (1989-1995)
Receptor Protein-Tyrosine Kinase (1994-1995)
Receptors, Colony-Stimulating Factor (1991-1995)

All MeSH Categories
- Chemicals and Drugs Category
  - Enzymes and Coenzymes [D08]
    - Enzymes [D08.811]
      - Transferases [D08.811.913]
        
        Phosphotransferases [D08.811.913.696]
        
        Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
        
        Protein Kinases [D08.811.913.696.620.682]
        
        Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
        
        Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
        
        Anaplastic Lymphoma Kinase [D08.811.913.696.620.682.725.400.002]
        
        c-Mer Tyrosine Kinase [D08.811.913.696.620.682.725.400.003]
        
        Discoidin Domain Receptors [D08.811.913.696.620.682.725.400.005] add_circle
        
        ErbB Receptors [D08.811.913.696.620.682.725.400.009] add_circle
        
        fms-Like Tyrosine Kinase 3 [D08.811.913.696.620.682.725.400.020]
        
        Proto-Oncogene Proteins c-kit [D08.811.913.696.620.682.725.400.050]
        
        Proto-Oncogene Proteins c-met [D08.811.913.696.620.682.725.400.075]
        
        Proto-Oncogene Proteins c-ret [D08.811.913.696.620.682.725.400.087]
        
        Receptor Tyrosine Kinase-like Orphan Receptors [D08.811.913.696.620.682.725.400.093]
        
        Receptor, Fibroblast Growth Factor, Type 1 [D08.811.913.696.620.682.725.400.177]
        
        Receptor, Fibroblast Growth Factor, Type 2 [D08.811.913.696.620.682.725.400.178]
        
        Receptor, Fibroblast Growth Factor, Type 3 [D08.811.913.696.620.682.725.400.179]
        
        Receptor, Fibroblast Growth Factor, Type 4 [D08.811.913.696.620.682.725.400.180]
        
        Receptor, IGF Type 1 [D08.811.913.696.620.682.725.400.185]
        
        Receptor, Insulin [D08.811.913.696.620.682.725.400.200]
        
        Receptor, Macrophage Colony-Stimulating Factor [D08.811.913.696.620.682.725.400.500]
        
        Receptor, trkA [D08.811.913.696.620.682.725.400.660]
        
        Receptor, trkB [D08.811.913.696.620.682.725.400.700]
        
        Receptor, trkC [D08.811.913.696.620.682.725.400.800]
        
        Receptors, Eph Family [D08.811.913.696.620.682.725.400.850] add_circle
        
        Receptors, Platelet-Derived Growth Factor [D08.811.913.696.620.682.725.400.900] add_circle
        
        Receptors, TIE [D08.811.913.696.620.682.725.400.925] add_circle
        
        Receptors, Vascular Endothelial Growth Factor [D08.811.913.696.620.682.725.400.950] add_circle

All MeSH Categories
- Chemicals and Drugs Category
  - Amino Acids, Peptides, and Proteins [D12]
    - Proteins [D12.776]
      - Intracellular Signaling Peptides and Proteins [D12.776.476]
        
        Protein-Tyrosine Kinases [D12.776.476.568]
        
        Receptor Protein-Tyrosine Kinases [D12.776.476.568.400]
        
        Anaplastic Lymphoma Kinase [D12.776.476.568.400.002]
        
        c-Mer Tyrosine Kinase [D12.776.476.568.400.003]
        
        Discoidin Domain Receptors [D12.776.476.568.400.005] add_circle
        
        ErbB Receptors [D12.776.476.568.400.009] add_circle
        
        fms-Like Tyrosine Kinase 3 [D12.776.476.568.400.020]
        
        Proto-Oncogene Proteins c-kit [D12.776.476.568.400.050]
        
        Proto-Oncogene Proteins c-met [D12.776.476.568.400.075]
        
        Proto-Oncogene Proteins c-ret [D12.776.476.568.400.087]
        
        Receptor Tyrosine Kinase-like Orphan Receptors [D12.776.476.568.400.093]
        
        Receptor, Fibroblast Growth Factor, Type 1 [D12.776.476.568.400.177]
        
        Receptor, Fibroblast Growth Factor, Type 2 [D12.776.476.568.400.178]
        
        Receptor, Fibroblast Growth Factor, Type 3 [D12.776.476.568.400.179]
        
        Receptor, Fibroblast Growth Factor, Type 4 [D12.776.476.568.400.180]
        
        Receptor, IGF Type 1 [D12.776.476.568.400.185]
        
        Receptor, Insulin [D12.776.476.568.400.200]
        
        Receptor, Macrophage Colony-Stimulating Factor [D12.776.476.568.400.500]
        
        Receptor, trkA [D12.776.476.568.400.660]
        
        Receptor, trkB [D12.776.476.568.400.700]
        
        Receptor, trkC [D12.776.476.568.400.800]
        
        Receptors, Eph Family [D12.776.476.568.400.850] add_circle
        
        Receptors, Platelet-Derived Growth Factor [D12.776.476.568.400.900] add_circle
        
        Receptors, TIE [D12.776.476.568.400.925] add_circle
        
        Receptors, Vascular Endothelial Growth Factor [D12.776.476.568.400.950] add_circle

All MeSH Categories
- Chemicals and Drugs Category
  - Amino Acids, Peptides, and Proteins [D12]
    - Proteins [D12.776]
      - Membrane Proteins [D12.776.543]
        
        Receptors, Cell Surface [D12.776.543.750]
        
        Receptor Protein-Tyrosine Kinases [D12.776.543.750.630]
        
        Anaplastic Lymphoma Kinase [D12.776.543.750.630.002]
        
        c-Mer Tyrosine Kinase [D12.776.543.750.630.003]
        
        Discoidin Domain Receptors [D12.776.543.750.630.005] add_circle
        
        ErbB Receptors [D12.776.543.750.630.009] add_circle
        
        fms-Like Tyrosine Kinase 3 [D12.776.543.750.630.020]
        
        Proto-Oncogene Proteins c-kit [D12.776.543.750.630.124]
        
        Proto-Oncogene Proteins c-met [D12.776.543.750.630.186]
        
        Proto-Oncogene Proteins c-ret [D12.776.543.750.630.217]
        
        Receptor Tyrosine Kinase-like Orphan Receptors [D12.776.543.750.630.233]
        
        Receptor, Fibroblast Growth Factor, Type 1 [D12.776.543.750.630.440]
        
        Receptor, Fibroblast Growth Factor, Type 2 [D12.776.543.750.630.441]
        
        Receptor, Fibroblast Growth Factor, Type 3 [D12.776.543.750.630.442]
        
        Receptor, Fibroblast Growth Factor, Type 4 [D12.776.543.750.630.443]
        
        Receptor, IGF Type 1 [D12.776.543.750.630.468]
        
        Receptor, Insulin [D12.776.543.750.630.484]
        
        Receptor, Macrophage Colony-Stimulating Factor [D12.776.543.750.630.492]
        
        Receptor, trkA [D12.776.543.750.630.496]
        
        Receptor, trkB [D12.776.543.750.630.498]
        
        Receptor, trkC [D12.776.543.750.630.499]
        
        Receptors, Eph Family [D12.776.543.750.630.500] add_circle
        
        Receptors, Platelet-Derived Growth Factor [D12.776.543.750.630.625] add_circle
        
        Receptors, TIE [D12.776.543.750.630.687] add_circle
        
        Receptors, Vascular Endothelial Growth Factor [D12.776.543.750.630.750] add_circle

All MeSH Categories
- Chemicals and Drugs Category
  - Amino Acids, Peptides, and Proteins [D12]
    - Proteins [D12.776]
      - Membrane Proteins [D12.776.543]
        
        Receptors, Cell Surface [D12.776.543.750]
        
        Receptors, Immunologic [D12.776.543.750.705]
        
        Receptors, Cytokine [D12.776.543.750.705.852]
        
        Receptors, Colony-Stimulating Factor [D12.776.543.750.705.852.150]
        
        Proto-Oncogene Proteins c-kit [D12.776.543.750.705.852.150.100]
        
        Receptor, Macrophage Colony-Stimulating Factor [D12.776.543.750.705.852.150.150]
        
        Receptors, Erythropoietin [D12.776.543.750.705.852.150.200]
        
        Receptors, Granulocyte Colony-Stimulating Factor [D12.776.543.750.705.852.150.280]
        
        Receptors, Granulocyte-Macrophage Colony-Stimulating Factor [D12.776.543.750.705.852.150.310] add_circle
        
        Receptors, Interleukin-3 [D12.776.543.750.705.852.150.360]

All MeSH Categories
- Chemicals and Drugs Category
  - Amino Acids, Peptides, and Proteins [D12]
    - Proteins [D12.776]
      - Membrane Proteins [D12.776.543]
        
        Receptors, Cell Surface [D12.776.543.750]
        
        Receptors, Peptide [D12.776.543.750.750]
        
        Receptors, Growth Factor [D12.776.543.750.750.400]
        
        Receptors, Colony-Stimulating Factor [D12.776.543.750.750.400.200]
        
        Proto-Oncogene Proteins c-kit [D12.776.543.750.750.400.200.170]
        
        Receptor, Macrophage Colony-Stimulating Factor [D12.776.543.750.750.400.200.200]
        
        Receptors, Erythropoietin [D12.776.543.750.750.400.200.340]
        
        Receptors, Granulocyte Colony-Stimulating Factor [D12.776.543.750.750.400.200.400]
        
        Receptors, Granulocyte-Macrophage Colony-Stimulating Factor [D12.776.543.750.750.400.200.420] add_circle
        
        Receptors, Interleukin-3 [D12.776.543.750.750.400.200.480]

All MeSH Categories
- Chemicals and Drugs Category
  - Amino Acids, Peptides, and Proteins [D12]
    - Proteins [D12.776]
      - Neoplasm Proteins [D12.776.624]
        
        Oncogene Proteins [D12.776.624.664]
        
        Proto-Oncogene Proteins [D12.776.624.664.700]
        
        B-Cell Lymphoma 3 Protein [D12.776.624.664.700.165]
        
        Bcl-2-Like Protein 11 [D12.776.624.664.700.025]
        
        c-Mer Tyrosine Kinase [D12.776.624.664.700.037]
        
        Chemokine CXCL1 [D12.776.624.664.700.049]
        
        Cyclin D1 [D12.776.624.664.700.100]
        
        Fibroblast Growth Factor 4 [D12.776.624.664.700.110]
        
        Fibroblast Growth Factor 6 [D12.776.624.664.700.112]
        
        fms-Like Tyrosine Kinase 3 [D12.776.624.664.700.114]
        
        Janus Kinase 2 [D12.776.624.664.700.117]
        
        KRIT1 Protein [D12.776.624.664.700.119]
        
        Kruppel-Like Factor 6 [D12.776.624.664.700.120]
        
        Lipocalin-2 [D12.776.624.664.700.123]
        
        Lymphocyte Specific Protein Tyrosine Kinase p56(lck) [D12.776.624.664.700.128]
        
        MDS1 and EVI1 Complex Locus Protein [D12.776.624.664.700.129]
        
        MutS Homolog 2 Protein [D12.776.624.664.700.130]
        
        Myeloid-Lymphoid Leukemia Protein [D12.776.624.664.700.148]
        
        N-Myc Proto-Oncogene Protein [D12.776.624.664.700.158]
        
        Pre-B-Cell Leukemia Transcription Factor 1 [D12.776.624.664.700.163]
        
        Proto-Oncogene Mas [D12.776.624.664.700.166]
        
        Proto-Oncogene Proteins c-abl [D12.776.624.664.700.167]
        
        Proto-Oncogene Proteins c-akt [D12.776.624.664.700.168]
        
        Proto-Oncogene Proteins c-bcl-2 [D12.776.624.664.700.169] add_circle
        
        Proto-Oncogene Proteins c-bcl-6 [D12.776.624.664.700.170]
        
        Proto-Oncogene Proteins c-bcr [D12.776.624.664.700.171] add_circle
        
        Proto-Oncogene Proteins c-cbl [D12.776.624.664.700.172]
        
        Proto-Oncogene Proteins c-crk [D12.776.624.664.700.174]
        
        Proto-Oncogene Proteins c-ets [D12.776.624.664.700.175] add_circle
        
        Proto-Oncogene Proteins c-fes [D12.776.624.664.700.177]
        
        Proto-Oncogene Proteins c-fos [D12.776.624.664.700.179]
        
        Proto-Oncogene Proteins c-fyn [D12.776.624.664.700.180]
        
        Proto-Oncogene Proteins c-hck [D12.776.624.664.700.181]
        
        Proto-Oncogene Proteins c-jun [D12.776.624.664.700.182]
        
        Proto-Oncogene Proteins c-kit [D12.776.624.664.700.183]
        
        Proto-Oncogene Proteins c-maf [D12.776.624.664.700.184]
        
        Proto-Oncogene Proteins c-mdm2 [D12.776.624.664.700.185]
        
        Proto-Oncogene Proteins c-met [D12.776.624.664.700.186]
        
        Proto-Oncogene Proteins c-mos [D12.776.624.664.700.187]
        
        Proto-Oncogene Proteins c-myb [D12.776.624.664.700.188]
        
        Proto-Oncogene Proteins c-myc [D12.776.624.664.700.189]
        
        Proto-Oncogene Proteins c-pim-1 [D12.776.624.664.700.191]
        
        Proto-Oncogene Proteins c-rel [D12.776.624.664.700.192]
        
        Proto-Oncogene Proteins c-ret [D12.776.624.664.700.194]
        
        Proto-Oncogene Proteins c-sis [D12.776.624.664.700.195]
        
        Proto-Oncogene Proteins c-vav [D12.776.624.664.700.198]
        
        Proto-Oncogene Proteins c-yes [D12.776.624.664.700.199]
        
        Proto-Oncogene Proteins p21(ras) [D12.776.624.664.700.200]
        
        Proto-Oncogene Proteins pp60(c-src) [D12.776.624.664.700.202]
        
        raf Kinases [D12.776.624.664.700.204] add_circle
        
        Receptor, ErbB-2 [D12.776.624.664.700.642]
        
        Receptor, ErbB-3 [D12.776.624.664.700.790]
        
        Receptor, ErbB-4 [D12.776.624.664.700.791]
        
        Receptor, Fibroblast Growth Factor, Type 3 [D12.776.624.664.700.792]
        
        Receptor, Macrophage Colony-Stimulating Factor [D12.776.624.664.700.800]
        
        Receptor, Notch4 [D12.776.624.664.700.815]
        
        Receptors, Thyroid Hormone [D12.776.624.664.700.830] add_circle
        
        RNA-Binding Protein EWS [D12.776.624.664.700.913]
        
        RNA-Binding Protein FUS [D12.776.624.664.700.915]
        
        RUNX1 Translocation Partner 1 Protein [D12.776.624.664.700.936]
        
        Stathmin [D12.776.624.664.700.957]
        
        T-Cell Acute Lymphocytic Leukemia Protein 1 [D12.776.624.664.700.960]
        
        Wnt-5a Protein [D12.776.624.664.700.962]
        
        Wnt1 Protein [D12.776.624.664.700.967]
        
        Wnt2 Protein [D12.776.624.664.700.978]
        
        Zinc Finger Protein GLI1 [D12.776.624.664.700.989]

MeSH 搜索器

Proto-Oncogene Proteins c-kit

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