MeSH 搜索器

c-Mer Tyrosine Kinase

A receptor tyrosine kinase that transduces signals from EXTRACELLULAR MATRIX to the CYTOPLASM by binding ligands such as GALECTIN 3. It regulates many physiologic processes that include cell survival, migration, differentiation, and PHAGOCYTOSIS of apoptotic cells and ROD PHOTORECEPTORS in the RETINAL PIGMENT EPITHELIUM. Mutations in the MERTK gene are associated with type 38 RETINITIS PIGMENTOSA; it also plays a critical role as an inhibitor of TOLL-LIKE RECEPTORS signaling.
推出的年份: 2018
副标题
树号: D08.811.913.696.620.682.725.400.003, D12.776.476.568.400.003, D12.776.543.750.630.003, D12.776.624.664.700.037
MeSH 单一 ID: D000076202
进入的组:
  • Kinase, c-Mer Tyrosine
  • Tyrosine Kinase, c-Mer
  • c Mer Tyrosine Kinase
  • c-Mer Proto-Oncogene Tyrosine Kinase
  • c Mer Proto Oncogene Tyrosine Kinase
  • MERTK
早前的内容:
  • Proto-Oncogene Proteins (1999-2017)
  • Receptor Protein-Tyrosine Kinases (1999-2017)

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