MeSH 搜索器

Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein

A caspase-like cysteine endopeptidase that also exhibits ubiquitin ligase activity. It contains an N-terminal DEATH DOMAIN, two IMMUNOGLOBULIN-LIKE DOMAINS, and localizes to the perinuclear region of MONOCYTES, where it functions in activation of NF-KAPPA B; it also binds to and activates TRAF6. Chromosomal translocations involving the MALT1 and BIRC2 genes are associated with MALT LYMPHOMA, and mutations in the MALT1 gene are associated with Type 12 IMMUNODEFICIENCY SYNDROMES.
推出的年份: 2018
副标题
树号: D08.811.277.656.262.500.126.775, D08.811.277.656.300.200.126.775, D08.811.464.938.750.233
MeSH 单一 ID: D000074884
进入的组:
  • Mucosa Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
  • MALT-1 Protein
  • MALT 1 Protein
  • MALT1 Protein
  • Paracaspase
  • MALT1 Paracaspase
  • Paracaspase, MALT1
早前的内容:
  • Caspases (1999-2017)
  • Neoplasm Proteins (1999-2017)

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