Revolutionizing Tooth Regeneration: Innovations from Stem Cells to Tissue Engineering

Bei M. Molecular genetics of tooth development. Curr Opin Genet Dev. 2009;19:504–10. https://doi.org/10.1016/j.gde.2009.09.002.

Article  PubMed  PubMed Central  Google Scholar 

Chen Y, Wang X, Wu Z, Jia S, Wan M. Epigenetic regulation of dental-derived stem cells and their application in pulp and periodontal regeneration. PeerJ. 2023;11:14550. https://doi.org/10.7717/peerj.14550.

Article  Google Scholar 

Jing J, Feng J, Yuan Y, Guo T, Lei J, Pei F, Ho T, Chai Y. Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis. Nat Commun. 2022;13:4803. https://doi.org/10.1038/s41467-022-32490-y.

Article  PubMed  PubMed Central  Google Scholar 

Radwan IA, Rady D, Abbass MMS, Moshy SE, AbuBakr N, Dörfer CE, El-Sayed KMF. Induced pluripotent stem cells in dental and nondental tissue regeneration: a review of an unexploited potential. Stem Cells Int. 2020;2020:1941629. https://doi.org/10.1155/2020/1941629.

Article  PubMed  PubMed Central  Google Scholar 

Alghadeer A, Hanson-Drury S, Patni AP, Ehnes DD, Zhao YT, Li Z, Phal A, Vincent TL, Lim YB, O’Day DR, Spurrell CH, Gogate AA, Zhang H, Devi A, Wang Y, Starita LM, Doherty D, Glass IA, Shendure J, Ruohola-Baker H. Single-cell census of human tooth development enables generation of human enamel. Dev Cell. 2023;58(2163–2180):9. https://doi.org/10.1016/j.devcel.2023.07.013.

Article  Google Scholar 

Torizal FG, Noorintan ST, Gania Z. Bioengineering tooth and periodontal organoids from stem and progenitor cells. Organoids. 2024;3(4):247–65. https://doi.org/10.3390/organoids3040015.

Article  Google Scholar 

Hosseinpour S, Walsh LJ, Moharamzadeh K. Regenerative approaches in dentistry. Springer Nature. 2021. https://doi.org/10.1007/978-3-030-59809-9.

Fu Z, Zhuang Y, Cui J, Sheng R, Tomás H, Rodrigues J, Zhao B, Wang X, Lin K. Development and challenges of cells- and materials-based tooth regeneration. Eng Regen. 2022;3(2):163–81. https://doi.org/10.1016/j.engreg.2022.04.003.

Tucker AS, Sharpe PT. Molecular genetics of tooth morphogenesis and patterning: the right shape in the right place. J Dent Res. 1999;78:826–34. https://doi.org/10.1177/00220345990780040201.

Article  PubMed  Google Scholar 

Li Y, Zhao X, Sun M, Pei D, Li A. Deciphering the epigenetic code of stem cells derived from dental tissues. Front Dental Med 2022;2. https://doi.org/10.3389/fdmed.2021.807046.

Zeng B, Liu G, Huang J. DNA methylation and histone modification in dental-derived mesenchymal stem cells. Stem Cell Reviews and Reports. 2022;18(8):2797–816. https://doi.org/10.1007/s12015-022-10413-0.

Article  PubMed  Google Scholar 

Hussain A, Tebyanian H, Khayatan D. The role of epigenetic in dental and oral regenerative medicine by different types of dental stem cells: a comprehensive overview. Stem Cells Int. 2022;2022:1–15. https://doi.org/10.1155/2022/5304860.

Article  Google Scholar 

Thesleff I. The genetic basis of tooth development and dental defects. Am J Med Genet A. 2006;140:2530–5. https://doi.org/10.1002/ajmg.a.31360.

Article  PubMed  Google Scholar 

Hu X, Zhang S, Chen G, Lin C, Huang Z, Chen Y, Zhang Y. Expression of SHH signaling molecules in the developing human primary dentition. BMC Dev Biol 2024;13(1). https://doi.org/10.1186/1471-213x-13-11.

Yu T, Klein OD. Molecular and cellular mechanisms of tooth development, homeostasis and repair. Development. 2020;147:184754. https://doi.org/10.1242/dev.184754.

Article  Google Scholar 

Baena ARY, Casasco A, Monti M. Hypes and hopes of stem cell therapies in dentistry: a review. Stem Cell Rev Rep. 2022;18(4):1294–308. https://doi.org/10.1007/s12015-021-10326-4.

Article  Google Scholar 

Hynes K, Menichanin D, Bright R, Ivanovski S, Hutmacher DW, Gronthos S, Bartold PM. Induced pluripotent stem cells: a new frontier for stem cells in dentistry. J Dent Res. 2015;94:1508–15. https://doi.org/10.1177/0022034515599769.

Article  PubMed  Google Scholar 

Hamano S, Sugiura R, Yamashita D, Tomokiyo A, Hasegawa D, Maeda H. Current application of IPS cells in the dental tissue regeneration. Biomedicines. 2022;10(12):3269. https://doi.org/10.3390/biomedicines10123269.

Article  PubMed  PubMed Central  Google Scholar 

Gao P, Liu S, Wang X, Ikeya M. Dental applications of induced pluripotent stem cells and their derivatives. Jpn Dent Sci Rev. 2022;58:162–71. https://doi.org/10.1016/j.jdsr.2022.03.002.

Article  PubMed  PubMed Central  Google Scholar 

Cho Y, Kim K, Lee Y, Seol Y. Dental-derived cells for regenerative medicine: stem cells, cell reprogramming, and transdifferentiation. J Periodontal Implant Sci. 2022;52(6):437. https://doi.org/10.5051/jpis.2103760188.

Article  PubMed  PubMed Central  Google Scholar 

Wang J, Zhao Z, Yang K, Bai Y. Research progress in cell therapy for oral diseases: focus on cell sources and strategies to optimize cell function. Front Bioeng Biotechnol. 2024;12:1340728. https://doi.org/10.3389/fbioe.2024.1340728.

Article  PubMed  PubMed Central  Google Scholar 

Hermans F, Hasevoets S, Vankelecom H, Bronckaers A, Lambrichts I. From pluripotent stem cells to organoids and bioprinting: recent advances in dental epithelium and ameloblast models to study tooth biology and regeneration. Stem Cell Reviews and Reports. 2024. https://doi.org/10.1007/s12015-024-10702-w.

Article  PubMed  PubMed Central  Google Scholar 

Liu L, Liu YF, Zhang J, Duan YZ, Jin Y. Ameloblasts serum-free conditioned medium: bone morphogenic protein 4-induced odontogenic differentiation of mouse induced pluripotent stem cells. J Tissue Eng Regen Med. 2016Jun;10(6):466–74. https://doi.org/10.1002/term.1742.

Article  PubMed  Google Scholar 

Wen S, Zheng X, Yin W, Liu Y, Wang R, Zhao Y, Liu Z, Li C, Zeng J, Rong M. Dental stem cell dynamics in periodontal ligament regeneration: from mechanism to application. Stem Cell Res Therapy 2024;15(1). https://doi.org/10.1186/s13287-024-04003-9.

Ariano A, Posa F, Storlino G, Mori G. Molecules inducing dental stem cells differentiation and bone regeneration: state of the art. Int J Mol Sci. 2023;24(12):9897. https://doi.org/10.3390/ijms24129897.

Article  PubMed  PubMed Central  Google Scholar 

Gao X, Wu Y, Liao L, Tian W. Oral organoids: progress and challenges. J Dent Res. 2021;100:454–63. https://doi.org/10.1177/0022034520983808.

Article  PubMed  Google Scholar 

Mendes-Pinheiro B, Campos J, Marote A, Soares-Cunha C, Nickels SL, Monzel AS, ... Salgado AJ. Treating Parkinson’s disease with human bone marrow mesenchymal stem cell secretome: a translational investigation using human brain organoids and different routes of in vivo administration. Cells. 2023;12(21):2565.https://doi.org/10.3390/cells12212565.

Hermans F, Hemeryck L, Bueds C, Pereiro MT, Hasevoets S, Kobayashi H, Lambrechts D, Lambrichts I, Bronckaers A, Vankelecom H. Organoids from mouse molar and incisor as new tools to study tooth-specific biology and development. Stem Cell Reports. 2023;18:1166–81. https://doi.org/10.1016/j.stemcr.2023.03.011.

Article  PubMed  PubMed Central  Google Scholar 

Hemeryck L, Hermans F, Chappell J, Kobayashi H, Lambrechts D, Lambrichts I, Bronckaers A, Vankelecom H. Organoids from human tooth showing epithelial stemness phenotype and differentiation potential. Cell Mol Life Sci. 2022;79:153. https://doi.org/10.1007/s00018-022-04183-8.

Article  PubMed  PubMed Central  Google Scholar 

Ma L, Rao N, Jiang H, Dai Y, Wang C, Yang H, Hu J. Small extracellular vesicles from dental follicle stem cells provide biochemical cues for periodontal tissue regeneration. Stem Cell Res Therapy, 2022;13(1). https://doi.org/10.1186/s13287-022-02767-6.

Bi R, Lyu P, Song Y, Li P, Song D, Cui C, Fan Y. Function of dental follicle progenitor/stem cells and their potential in regenerative medicine: from mechanisms to applications. Biomolecules. 2021;11(7):997. https://doi.org/10.3390/biom11070997.

Article  PubMed  PubMed Central  Google Scholar 

Muniraj G, Tan RHS, Dai Y, Wu R, Alberti M, Sriram G. Microphysiological modeling of gingival tissues and host‐material interactions using Gingiva‐on‐Chip. Adv Healthc Mater. 2023;12(32). https://doi.org/10.1002/adhm.202301472.

França CM, Tahayeri A, Rodrigues NS, Ferdosian S, Puppin-Rontani R, Ferracane JL, Bertassoni LE. The tooth on-a-chip: a microphysiologic model system mimicking the pulp-dentin interface and its interaction with biomaterials. bioRxiv (Cold Spring Harbor Laboratory). 2019. https://doi.org/10.1101/748053.

Macalester W. Biofabrication of a ‘Tooth-on-a-chip’Model (Doctoral dissertation, University of Bristol). 2022.

박병주. Reparative dentin formation by dental pulp transplantation in a biomimetic microfluidic system (Doctoral dissertation, 서울대학교 대학원). 2024.

Huang C, Sanaei F, Verdurmen WPR, Yang F, Ji W, Walboomers XF. The application of organs-on-a-chip in dental, oral, and craniofacial research. J Dent Res. 2023;102(4):364–75. https://doi.org/10.1177/00220345221145555.

Article  PubMed  Google Scholar 

Soares DG, Bordini EA, Swanson WB, de Souza Costa CA, Bottino MC. Platform technologies for regenerative endodontics from multifunctional biomaterials to tooth-on-a-chip strategies. Clin Oral Invest. 2021;25:4749–79. https://doi.org/10.1007/s00784-021-04013-4.

Article  Google Scholar 

Farshidfar N, Assar S, Amiri MA, Sahmeddini S, Hamedani S, Zarei M, Tayebi L. The feasible application of microfluidic tissue/organ-on-a-chip as an impersonator of oral tissues and organs: a direction for future research. Bio-Design and Manufacturing. 2023;6(4):478–506. https://doi.org/10.1007/s42242-023-00235-5.

Article  Google Scholar 

Raina R. Bioactive glass in dentistry: a review. J Adv Med Dental Sci Res. 2023;11(6):121–4. https://doi.org/10.21276/jamdsr.

Article 

留言 (0)

沒有登入
gif