Lysosome quality control in health and neurodegenerative diseases

De Duve C, Wattiaux R. Functions of lysosomes. Annu Rev Physiol. 1966;28:435–92.

Article  PubMed  Google Scholar 

De Duve C, Pressman BC, Gianetto R, Wattiaux R, Applemans F. Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue. Biochem J. 1955;60(4):604–17. https://doi.org/10.1042/bj0600604.

Article  PubMed  PubMed Central  Google Scholar 

Seglen PO, Gordon PBHI. Non-selective autophagy. Semin Cell Biol. 1990;1(6):441–8.

CAS  PubMed  Google Scholar 

Sancak Y, Bar-Peled L, Zoncu R, Markhard AL, Nada S, Sabatini DM. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell. 2010;141(2):290–303.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zoncu R, Bar-Peled L, Efeyan A, Wang S, Sancak Y, Sabatini DM. mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H±ATPase. Science. 2011;334(6056):678–83.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gray MA, Choy CH, Dayam RM, Escobar EO, Somerville A, Xiao X, et al. Phagocytosis enhances lysosomal and bactericidal properties by activating the transcription factor TFEB Matthew. Curr Biol. 2017;26(15):1955–64.

Article  Google Scholar 

Reddy A, Caler EV, Andrews NW, Haven N. Plasma membrane repair is mediated by Ca 2 ± regulated exocytosis of lysosomes. Cell. 2001;106:157–69.

Article  CAS  PubMed  Google Scholar 

Encarnação M, Espada L, Escrevente C, Mateus D, Ramalho J, Michelet X, et al. A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair. J Cell Biol. 2016. https://doi.org/10.1083/jcb.201511093.

Article  PubMed  PubMed Central  Google Scholar 

Lim CY, Zoncu R. The lysosome as a command-and-control center for cellular metabolism. J Cell Biol. 2016;214(6):653–64.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lawrence RE, Zoncu R. The lysosome as a cellular centre for signalling, metabolism and quality control. Nat Cell Biol. 2019;21(2):133–42.

Article  CAS  PubMed  Google Scholar 

Repnik U, Česen MH, Turk B. The endolysosomal system in cell death and survival. Cold Spring Harb Perspect Biol. 2013;5(1): a008755.

Article  PubMed  PubMed Central  Google Scholar 

Sun A. Lysosomal storage disease overview. Ann Transl Med. 2018. https://doi.org/10.21037/atm.2018.11.39.

Article  PubMed  PubMed Central  Google Scholar 

Parenti G, Andria G, Ballabio A. Lysosomal storage diseases : from pathophysiology to therapy. Annu Rev Med. 2015. https://doi.org/10.1146/annurev-med-122313-085916.

Article  PubMed  Google Scholar 

Marques ARA, Saftig P. Lysosomal storage disorders—challenges, concepts and avenues for therapy: beyond rare diseases. J Cell Sci. 2019. https://doi.org/10.1242/jcs.221739.

Article  PubMed  Google Scholar 

Kirkegaard T, Jäättelä M. Biochimica et biophysica acta lysosomal involvement in cell death and cancer. BBA Mol Cell Res. 2009;1793(4):746–54.

CAS  Google Scholar 

Davidson SM, Vander HMG. Critical functions of the lysosome in cancer biology. Annu Rev Pharmacol Toxicol. 2017;57:481–510.

Article  CAS  PubMed  Google Scholar 

Herbst S, Campbell P, Harvey J, Bernard EM, Papayannopoulos V, Wood NW, et al. LRRK 2 activation controls the repair of damaged endomembranes in macrophages. EMBO J. 2020;39(18):1–14.

Article  Google Scholar 

Feng T, Mai S, Roscoe JM, Sheng RR, Ullah M, Zhang J, et al. Loss of TMEM106B and PGRN leads to severe lysosomal abnormalities and neurodegeneration in mice. EMBO Rep. 2020;21(10): e50219.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tedeschi V, Petrozziello T, Secondo A. Calcium dyshomeostasis and lysosomal Ca2+ dysfunction in amyotrophic lateral sclerosis. Cells. 2019. https://doi.org/10.3390/cells8101216.

Article  PubMed  PubMed Central  Google Scholar 

Cortes CJ, La Spada AR. TFEB dysregulation as a driver of autophagy dysfunction in neurodegenerative disease: molecular mechanisms, cellular processes, and emerging therapeutic opportunities. Neurobiol Dis. 2018. https://doi.org/10.1016/j.nbd.2018.05.012.

Article  PubMed  PubMed Central  Google Scholar 

Wang Y, Martinez-Vicente M, Krüger U, Kaushik S, Wong E, Mandelkow EM, et al. Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing. Hum Mol Genet. 2009;18(21):4153–70.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dodson MW, Zhang T, Jiang C, Chen S, Guo M. Roles of the Drosophila LRRK2 homolog in Rab7-dependent lysosomal positioning. Hum Mol Genet. 2012;21(6):1350–63.

Article  CAS  PubMed  Google Scholar 

Tohnai G, Adachi H, Katsuno M, Doi H, Matsumoto S, Kondo N, et al. Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy. Hum Mol Genet. 2014. https://doi.org/10.1093/hmg/ddu066.

Article  PubMed  Google Scholar 

Mathis S, Goizet C, Soulages A, Vallat JM, Le MG. Genetics of amyotrophic lateral sclerosis: a review. J Neurol Sci. 2019;399(February):217–26.

Article  CAS  PubMed  Google Scholar 

Carmona-gutierrez D, Hughes AL, Madeo F, Ruckenstuhl C. The crucial impact of lysosomes in aging and longevity. Age Res Rev. 2016;32:2–12.

Article  CAS  Google Scholar 

Peters C, von Figura K. Biogenesis of lysosomal membranes. FEBS Lett. 1994;346(1):108–14.

Article  CAS  PubMed  Google Scholar 

Schwake M, Schröder B, Saftig P. Lysosomal membrane proteins and their central role in physiology. Traffic. 2013;14(7):739–48.

Article  CAS  PubMed  Google Scholar 

Schröder B, Wrocklage C, Pan C, Jäger R, Kösters B, Schäfer H, et al. Integral and associated lysosomal membrane proteins. Traffic. 2007;8(12):1676–86.

Article  PubMed  Google Scholar 

Schröder BA, Wrocklage C, Hasilik A, Saftig P. The proteome of lysosomes. Proteomics. 2010;10(22):4053–76.

Article  PubMed  Google Scholar 

Lewis V, Green SA, Marsh M, Vlhko P, Helenius A, Mellman I. Glycoproteins of the lysosomal membrane. J Cell Biol. 1985;100(6):1839–47.

Article  CAS  PubMed  Google Scholar 

Andrejewski N, Punnonen EL, Guhde G, Tanaka Y, Lüllmann-Rauch R, Hartmann D, et al. Normal lysosomal morphology and function in LAMP-1-deficient mice. J Biol Chem. 1999;274(18):12692–701.

Article  CAS  PubMed  Google Scholar 

Tanaka Y, Guhde G, Suter A, Eskelinen EL, Hartmann D, Lüllmann-Rauch R, et al. Accumulation of autophagic vacuoles and cardiomyopathy LAMP-2-deficient mice. Nature. 2000;406(6798):902–6.

Article  CAS  PubMed 

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