Li X, Zhang Z, Wang Z, Gutiérrez-Castrellón P. Cell deaths: Involvement in the pathogenesis and intervention therapy of COVID-19. Signal Transduct Target Ther. 2022;7(1):186.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Renia L, Ng LFP. Acquired immunity against SARS-CoV-2 infection and vaccination. EMBO Mol Med. 2023;15(12): e16345.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vardar Acar N, Özgül RK. The bridge between cell survival and cell death: reactive oxygen species-mediated cellular stress. Excli J. 2023;2:520–55.

Google Scholar 

Lee BWL, Ghode P, Ong DST. Redox regulation of cell state and fate. Redox Biol. 2019;25: 101056.

Article  CAS  PubMed  Google Scholar 

Villalpando-Rodriguez GE, Gibson SB. Reactive oxygen species (ROS) regulates different types of cell death by acting as a rheostat. Oxid Med Cell Longev. 2021;2021:9912436.

Article  PubMed  PubMed Central  Google Scholar 

Lennicke C, Cochemé HM. Redox metabolism: ROS as specific molecular regulators of cell signaling and function. Mol Cell. 2021;81(18):3691–707.

Article  CAS  PubMed  Google Scholar 

Forrester SJ, Kikuchi DS, Hernandes MS, Xu Q, Griendling KK. Reactive oxygen species in metabolic and inflammatory signaling. Circ Res. 2018;122(6):877–902.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li X, Gao J. Precise modulation and use of reactive oxygen species for immunotherapy. Sci Adv. 2024;10(20):eadl0479.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sander WJ, Fourie C. Reactive oxygen species as potential antiviral targets. Rev Med Virol. 2022;32(1): e2240.

Article  CAS  PubMed  Google Scholar 

Trepte P, Secker C, Olivet J, Blavier J, Kostova S, Maseko SB, et al. AI-guided pipeline for protein–protein interaction drug discovery identifies a SARS-CoV-2 inhibitor. Mol Sys Bio. 2024. https://doi.org/10.1038/s44320-024-00019-8.

Article  Google Scholar 

Imre G. Cell death signalling in virus infection. Cell Signal. 2020;76: 109772.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Reshi ML, Su YC, Hong JR. RNA viruses: ROS-mediated cell death. Int J Cell Biol. 2014;2014: 467452.

Article  PubMed  PubMed Central  Google Scholar 

Bertheloot D, Latz E. Necroptosis, pyroptosis and apoptosis: an intricate game of cell death. Cell Mol Immunol. 2021;18(5):1106–21.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yuan C, Ma Z, Xie J, Li W, Su L, Zhang G, et al. The role of cell death in SARS-CoV-2 infection. Signal Transduct Target Ther. 2023;8(1):357.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lushchak VI. Free radicals, reactive oxygen species, oxidative stress and its classification. Chem Biol Interact. 2014;224:164–75.

Article  CAS  PubMed  Google Scholar 

Feng Y, Pan Z, Wang Z, Lei Z, Yang S, Zhao H. MERS-CoV nsp1 regulates autophagic flux via mTOR signalling and dysfunctional lysosomes. Emerg Microbes Infect. 2022;11(1):2529–43.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shin N, Pyo CW, Jung KI, Choi SY. Influenza A virus PB1-F2 is involved in regulation of cellular redox state in alveolar epithelial cells. Biochem Biophys Res Commun. 2015;459(4):699–705.

Article  CAS  PubMed  Google Scholar 

Danthi P. Viruses and the diversity of cell death. Annu Rev Virol. 2016;3(1):533–53.

Article  CAS  PubMed  Google Scholar 

Morais da Silva M, Lira de Lucena AS, Paiva Júnior SSL, Florêncio De Carvalho VM, Santana de Oliveira PS, da Rosa MM, et al. Cell death mechanisms involved in cell injury caused by SARS-CoV-2. Rev Med Virol. 2022;32(3):e2292.

Article  CAS  PubMed  Google Scholar 

Thiam HR, Wong SL, Wagner DD, Waterman CM. Cellular mechanisms of NETosis. Annu Rev Cell Dev Biol. 2020;36:191–218.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sørensen OE, Borregaard N. Neutrophil extracellular traps—the dark side of neutrophils. J Clin Invest. 2016;126(5):1612–20.

Article  PubMed  PubMed Central  Google Scholar 

Narasaraju T, Tang BM, Herrmann M, Muller S, Chow VTK, Radic M. Neutrophilia and NETopathy as key pathologic drivers of progressive lung impairment in patients with COVID-19. Front Pharmacol. 2020;11:870.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Arcanjo A, Logullo J, Menezes CCB, de Souza Carvalho Giangiarulo TC, Dos Reis MC, de Castro GMM, et al. The emerging role of neutrophil extracellular traps in severe acute respiratory syndrome coronavirus 2 (COVID-19). Sci Rep. 2020;10(1):19630.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kvietys PR, Fakhoury HMA, Kadan S, Yaqinuddin A, Al-Mutairy E, Al-Kattan K. COVID-19: lung-centric immunothrombosis. Front Cell Infect Microbiol. 2021;11:679878.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vorobjeva NV, Chernyak BV. NETosis: molecular mechanisms, role in physiology and pathology. Biochemistry (Mosc). 2020;85(10):1178–90.

Article  CAS  PubMed  Google Scholar 

Metzler KD, Goosmann C, Lubojemska A, Zychlinsky A, Papayannopoulos V. A myeloperoxidase-containing complex regulates neutrophil elastase release and actin dynamics during NETosis. Cell Rep. 2014;8(3):883–96.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Park HH, Park W, Lee YY, Kim H, Seo HS, Choi DW, et al. Bioinspired DNase-I-coated melanin-like nanospheres for modulation of infection-associated NETosis dysregulation. Adv Sci (Weinh). 2021;8(19): e2103748.

Article  PubMed  Google Scholar 

Porto BN, Stein RT. Neutrophil extracellular traps in pulmonary diseases: too much of a good thing? Front Immunol. 2016;7:311.

Article  PubMed  PubMed Central  Google Scholar 

Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE, et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell. 2012;149(5):1060–72.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jiang X, Stockwell BR. Ferroptosis: mechanisms, biology and role in disease. Nat Rev Mol Cell Biol. 2021;22(4):266–82.

Article  PubMed  PubMed Central  Google Scholar 

Zheng D, Li F, Wang S, Liu P-S, Xie X. High-content image screening to identify chemical modulators for peroxisome and ferroptosis. Cell Mol Biol Lett. 2024;29(1):26.