m6A-modified circCacna1c regulates necroptosis and ischemic myocardial injury by inhibiting Hnrnpf entry into the nucleus

Dorn GW 2nd. Apoptotic and non-apoptotic programmed cardiomyocyte death in ventricular remodelling. Cardiovasc Res. 2009;81(3):465–73.

Article  CAS  PubMed  Google Scholar 

Zhang J, Bolli R, Garry DJ, Marbán E, Menasché P, Zimmermann WH, et al. Basic and translational research in cardiac repair and regeneration: JACC state-of-the-art review. J Am Coll Cardiol. 2021;78(21):2092–105.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Del Campo CV, Liaw NY, Gunadasa-Rohling M, Matthaei M, Braga L, Kennedy T, et al. Regenerative potential of epicardium-derived extracellular vesicles mediated by conserved miRNA transfer. Cardiovasc Res. 2022;118(2):597–611.

Article  PubMed  Google Scholar 

Nakada Y, Canseco DC, Thet S, Abdisalaam S, Asaithamby A, Santos CX, et al. Hypoxia induces heart regeneration in adult mice. Nature. 2017;541(7636):222–7.

Article  CAS  PubMed  Google Scholar 

Ao X, Ding W, Li X, Xu Q, Chen X, Zhou X, et al. Non-coding RNAs regulating mitochondrial function in cardiovascular diseases. J Mol Med. 2023;101(5):501–26.

Article  PubMed  Google Scholar 

Liu Y, Ding W, Wang J, Ao X, Xue J. Non-coding RNA-mediated modulation of ferroptosis in cardiovascular diseases. Biomed Pharmacother = Biomedecine pharmacotherapie. 2023;164: 114993.

Article  CAS  PubMed  Google Scholar 

Horvath C, Kararigas G. Sex-dependent mechanisms of cell death modalities in cardiovascular disease. Can J Cardiol. 2022;38(12):1844–53.

Article  PubMed  Google Scholar 

Khoury MK, Gupta K, Franco SR, Liu B. Necroptosis in the pathophysiology of disease. Am J Pathol. 2020;190(2):272–85.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kung G, Konstantinidis K, Kitsis RN. Programmed necrosis, not apoptosis, in the heart. Circ Res. 2011;108(8):1017–36.

Article  CAS  PubMed  Google Scholar 

Li J, McQuade T, Siemer AB, Napetschnig J, Moriwaki K, Hsiao YS, et al. The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis. Cell. 2012;150(2):339–50.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang T, Zhang Y, Cui M, Jin L, Wang Y, Lv F, et al. CaMKII is a RIP3 substrate mediating ischemia- and oxidative stress-induced myocardial necroptosis. Nat Med. 2016;22(2):175–82.

Article  PubMed  Google Scholar 

He S, Wang L, Miao L, Wang T, Du F, Zhao L, et al. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell. 2009;137(6):1100–11.

Article  CAS  PubMed  Google Scholar 

DeRoo E, Zhou T, Liu B. The role of RIPK1 and RIPK3 in cardiovascular disease. Int J Mol Sci. 2020;21(21):8174.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen LL. The expanding regulatory mechanisms and cellular functions of circular RNAs. Nat Rev Mol Cell Biol. 2020;21(8):475–90.

Article  CAS  PubMed  Google Scholar 

Liu Y, Ding W, Wang J, Ao X, Xue J. Non-coding RNAs in lung cancer: molecular mechanisms and clinical applications. Front Oncol. 2023;13:1256537.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhou X, Ao X, Jia Z, Li Y, Kuang S, Du C, et al. Non-coding RNA in cancer drug resistance: underlying mechanisms and clinical applications. Front Oncol. 2022;12: 951864.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Devaux Y, Creemers EE, Boon RA, Werfel S, Thum T, Engelhardt S, et al. Circular RNAs in heart failure. Eur J Heart Fail. 2017;19(6):701–9.

Article  CAS  PubMed  Google Scholar 

Altesha MA, Ni T, Khan A, Liu K, Zheng X. Circular RNA in cardiovascular disease. J Cell Physiol. 2019;234(5):5588–600.

Article  CAS  PubMed  Google Scholar 

Lim GB. Circular RNA prevents doxorubicin-induced cardiotoxicity. Nat Rev Cardiol. 2022;19(9):574.

Article  CAS  PubMed  Google Scholar 

Li M, Ding W, Tariq MA, Chang W, Zhang X, Xu W, et al. A circular transcript of ncx1 gene mediates ischemic myocardial injury by targeting miR-133a-3p. Theranostics. 2018;8(21):5855–69.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yin L, Tang Y, Yuan Y. An overview of the advances in research on the molecular function and specific role of circular RNA in cardiovascular diseases. Biomed Res Int. 2022;2022:5154122.

Article  PubMed  PubMed Central  Google Scholar 

Sun YH, Zhao TJ, Li LH, Wang Z, Li HB. Emerging role of N(6)-methyladenosine in the homeostasis of glucose metabolism. Am J Physiol Endocrinol Metab. 2024;326(1):E1-e13.

Article  PubMed  Google Scholar 

Zhang L, Hou C, Chen C, Guo Y, Yuan W, Yin D, et al. The role of N(6)-methyladenosine (m(6)A) modification in the regulation of circRNAs. Mol Cancer. 2020;19(1):105.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Park OH, Ha H, Lee Y, Boo SH, Kwon DH, Song HK, et al. Endoribonucleolytic cleavage of m(6)A-containing RNAs by RNase P/MRP complex. Mol Cell. 2019;74(3):494-507.e498.

Article  CAS  PubMed  Google Scholar 

Qin S, Mao Y, Chen X, Xiao J, Qin Y, Zhao L. The functional roles, cross-talk and clinical implications of m6A modification and circRNA in hepatocellular carcinoma. Int J Biol Sci. 2021;17(12):3059–79.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu C, Gu L, Deng W, Meng Q, Li N, Dai G, et al. N6-Methyladenosine RNA methylation in cardiovascular diseases. Front Cardiovasc Med. 2022;9: 887838.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang JX, Zhang XJ, Li Q, Wang K, Wang Y, Jiao JQ, et al. MicroRNA-103/107 regulate programmed necrosis and myocardial ischemia/reperfusion injury through targeting FADD. Circ Res. 2015;117(4):352–63.

Article  CAS  PubMed  Google Scholar 

Wang JX, Jiao JQ, Li Q, Long B, Wang K, Liu JP, et al. miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1. Nat Med. 2011;17(1):71–8.

Article  PubMed  Google Scholar 

Luo Z, Rong Z, Zhang J, Zhu Z, Yu Z, Li T, et al. Circular RNA circCCDC9 acts as a miR-6792-3p sponge to suppress the progression of gastric cancer through regulating CAV1 expression. Mol Cancer. 2020;19(1):86.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zheng Q, Bao C, Guo W, Li S, Chen J, Chen B, et al. Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs. Nat Commun. 2016;7:11215.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dominissini D, Moshitch-Moshkovitz S, Salmon-Divon M, Amariglio N, Rechavi G. Transcriptome-wide mapping of N(6)-methyladenosine by m(6)A-seq based on immunocapturing and massively pa

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