Adams RP (2007) Identification of essential oil components by gas chromatography/mass spectrometry. Allured Publishing Corporation, Carol Stream, Ilinois, EUA

Google Scholar 

Aguiar DP, de Souza CP et al (2021) Prevalence of chronic pain in Brazil: systematic review. Brazilian J Pain. https://doi.org/10.5935/2595-0118.20210041

Article  Google Scholar 

Ahmadimoghaddam D, Zarei M, Mohammadi S et al (2021) Bupleurum falcatum L alleviates nociceptive and neuropathic pain: potential mechanisms of action. J Ethnopharmacol. https://doi.org/10.1016/j.jep.2021.113990

Article  PubMed  Google Scholar 

Andersen ME, Thomas RS, Gaido KW, Conolly RB (2005) Dose–response modeling in reproductive toxicology in the systems biology era. Reprod Toxicol 19:327–337. https://doi.org/10.1016/j.reprotox.2004.12.004

Article  CAS  PubMed  Google Scholar 

Bai X, Li Y, Li Y et al (2023) Antinociceptive activity of doliroside B. Pharm Biol 61:201–212. https://doi.org/10.1080/13880209.2022.2163407

Article  CAS  PubMed  PubMed Central  Google Scholar 

Barbosa AGR, Tintino CDMO, Pessoa RT et al (2022) Anti-inflammatory and antinociceptive effect of Hyptis martiusii BENTH leaves essential oil. Biotechnol Reports 35:e00756. https://doi.org/10.1016/j.btre.2022.e00756

Article  CAS  Google Scholar 

de Barros L et al (2022) Chemometric analysis of the seasonal variation in the essential oil composition and antioxidant activity of a new geraniol chemotype of Lippia alba (Mill) Wilson from the Brazilian Amazon. Biochem Syst Ecol. https://doi.org/10.1016/j.bse.2022.104503

Article  Google Scholar 

Bindu S, Mazumder S, Bandyopadhyay U (2020) Non-steroidal anti-inflammatory drugs (NSAIDs) and organ damage: A current perspective. Biochem Pharmacol 180:114147. https://doi.org/10.1016/j.bcp.2020.114147

Article  CAS  PubMed  PubMed Central  Google Scholar 

Boukhatem MN, Darwish NHE, Sudha T et al (2020) In Vitro Antifungal and Topical Anti-Inflammatory Properties of Essential Oil from Wild-Growing Thymus vulgaris (Lamiaceae) Used for Medicinal Purposes in Algeria: A New Source of Carvacrol. Sci Pharm 88:33. https://doi.org/10.3390/scipharm88030033

Article  CAS  Google Scholar 

Bunse M, Daniels R, Gründemann C et al (2022) Essential oils as multicomponent mixtures and their potential for human health and well-being. Front Pharmacol. https://doi.org/10.3389/fphar.2022.956541

Article  PubMed  PubMed Central  Google Scholar 

Conegundes JLM, da Silva JM, de Mendes R, F, et al (2021) Anti-inflammatory and antinociceptive activity of Siparuna guianensis Aublet, an amazonian plant traditionally used by indigenous communities. J Ethnopharmacol 265:113344. https://doi.org/10.1016/j.jep.2020.113344

Article  CAS  PubMed  Google Scholar 

Costa-Silva JH, Lima CR, Silva EJR et al (2008) Acute and subacute toxicity of the Carapa guianensis Aublet (Meliaceae) seed oil. J Ethnopharmacol 116:495–500. https://doi.org/10.1016/j.jep.2007.12.016

Article  CAS  PubMed  Google Scholar 

Costa WK et al (2022) Oral administration of essential oil from Psidium glaziovianum Kiaersk leaves alleviates pain and inflammation in mice. Inflammopharmacology 30:599–607. https://doi.org/10.1007/s10787-022-00940-0

Article  CAS  PubMed  Google Scholar 

Da Fonseca A, Fernandes Ribeiro Dantas L, Rodrigues J et al (2021) PA-Int5: An isatin-thiosemicarbazone derivative that exhibits anti-nociceptive and anti-inflammatory effects in Swiss mice. Biomed Reports 15:61. https://doi.org/10.3892/br.2021.1437

Article  CAS  Google Scholar 

Deng J, Han J, Chen J et al (2021) Comparison of analgesic activities of aconitine in different mice pain models. PLoS ONE 16:e0249276. https://doi.org/10.1371/journal.pone.0249276

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dey R, Dey S, Samadder A et al (2022) Natural Inhibitors against Potential Targets of Cyclooxygenase, Lipoxygenase and Leukotrienes. Comb Chem High Throughput Screen 25:2341–2357. https://doi.org/10.2174/1386207325666210917111847

Article  CAS  PubMed  Google Scholar 

Dubuisson D, Dennis SG (1977) The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats. Pain 4:161–174. https://doi.org/10.1016/0304-3959(77)90130-0

Article  CAS  PubMed  Google Scholar 

FDA (2003) Redbook 2000: IV.B.1. General Guidelines for Designing and Conducting Toxicity Studies. https://www.fda.gov/regulatory-information/search-fda-guidance-documents/redbook-2000-ivb1-general-guidelines-designing-and-conducting-toxicity-studies#obs

Gábor M Models of Acute Inflammation in the Ear. In: Inflammation Protocols. Humana Press, New Jersey, pp 129–138

Gauvin-Bialecki A, Marodon C (2008) Essential oil of Ayapana triplinervis from Reunion Island: A good natural source of thymohydroquinone dimethyl ether. Biochem Syst Ecol 36:853–858. https://doi.org/10.1016/j.bse.2008.09.006

Article  CAS  Google Scholar 

Grossi MA., Barreto JNV (2024) Ayapana in Flora e Funga do Brasil. In: Jard. Botânico do Rio Janeiro. https://floradobrasil.jbrj.gov.br/FB117086. Accessed 15 Apr 2024

Guo B, Zhao C, Zhang C et al (2022) Elucidation of the anti-inflammatory mechanism of Er Miao San by integrative approach of network pharmacology and experimental verification. Pharmacol Res 175:106000. https://doi.org/10.1016/j.phrs.2021.106000

Article  CAS  PubMed  Google Scholar 

Haddad JG, Picard M, Bénard S et al (2019) Ayapana triplinervis Essential Oil and Its Main Component Thymohydroquinone Dimethyl Ether Inhibit Zika Virus at Doses Devoid of Toxicity in Zebrafish. Molecules 24:3447. https://doi.org/10.3390/molecules24193447

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hunskaar S, Fasmer OB, Hole K (1985) Formalin test in mice, a useful technique for evaluating mild analgesics. J Neurosci Methods 14:69–76. https://doi.org/10.1016/0165-0270(85)90116-5

Article  CAS  PubMed  Google Scholar 

Ibrahim B, Sowemimo A, van Rooyen A, Van de Venter M (2012) Antiinflammatory, analgesic and antioxidant activities of Cyathula prostrata (Linn) Blume (Amaranthaceae). J Ethnopharmacol 141:282–289. https://doi.org/10.1016/j.jep.2012.02.032

Article  CAS  PubMed  Google Scholar 

Jin W-Y, Liu Z, Liu D, Yu L-C (2010) Antinociceptive effects of galanin in the central nucleus of amygdala of rats, an involvement of opioid receptors. Brain Res 1320:16–21. https://doi.org/10.1016/j.brainres.2009.12.060

Article  CAS  PubMed  Google Scholar 

Jones P, Lamdin R, Dalziel SR (2020) Oral non-steroidal anti-inflammatory drugs versus other oral analgesic agents for acute soft tissue injury. Cochrane Database Syst Rev. https://doi.org/10.1002/14651858.CD007789.pub3

Article  PubMed  PubMed Central  Google Scholar 

Karpiński TM (2020) Essential Oils of Lamiaceae Family Plants as Antifungals. Biomolecules 10:103. https://doi.org/10.3390/biom10010103

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lobato Rodrigues AB, Martins RL, de Rabelo É, M, et al (2021) Development of nano-emulsions based on Ayapana triplinervis essential oil for the control of Aedes aegypti larvae. PLoS ONE 16:e0254225. https://doi.org/10.1371/journal.pone.0254225

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lopes DM, Cater HL, Thakur M et al (2019) A refinement to the formalin test in mice. F1000Research. https://doi.org/10.12688/f1000research.18338.2

Article  PubMed  PubMed Central  Google Scholar 

Malpezzi-Marinho ELA, Molska GR, Freire LIGP et al (2019) Effects of hydroalcoholic extract of Solidago chilensis Meyen on nociception and hypernociception in rodents. BMC Complement Altern Med 19:72. https://doi.org/10.1186/s12906-019-2478-8

Article  PubMed  PubMed Central