Genetically predicted immune cells mediate the association between gut microbiota and neuropathy pain

Abecasis GR, Altshuler D, Auton A, Brooks LD, Durbin RM, Gibbs RA, Hurles ME, McVean GA (2010) A map of human genome variation from population-scale sequencing. Nature 467:1061–1073

Article  PubMed  Google Scholar 

Ahmed A, Adiga V, Nayak S, Uday Kumar JAJ, Dhar C, Sahoo PN, Sundararaj BK, Souza GD, Vyakarnam A (2018) Circulating HLA-DR+CD4+ effector memory T cells resistant to CCR5 and PD-L1 mediated suppression compromise regulatory T cell function in tuberculosis. PLoS Pathog 14:e1007289

Article  PubMed  PubMed Central  Google Scholar 

Attal N, Bouhassira D, Colvin L (2023) Advances and challenges in neuropathic pain: a narrative review and future directions. Br J Anaesth 131:79–92

Article  PubMed  Google Scholar 

Austin PJ, Moalem-Taylor G (2010) The neuro-immune balance in neuropathic pain: involvement of inflammatory immune cells, immune-like glial cells and cytokines. J Neuroimmunol 229:26–50

Article  CAS  PubMed  Google Scholar 

Bäckhed F, Ding H, Wang T, Hooper LV, Koh GY, Nagy A, Semenkovich CF, Gordon JI (2004) The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci USA 101:15718–15723

Article  PubMed  PubMed Central  Google Scholar 

Barcelon EE, Cho WH, Jun SB, Lee SJ (2019) Brain microglial activation in chronic pain-associated affective disorder. Front Neurosci 13:213

Article  PubMed  PubMed Central  Google Scholar 

Bethea JR, Fischer R (2021) Role of peripheral immune cells for development and recovery of chronic pain. Front Immunol 12:641588

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bowden J, Davey Smith G, Burgess S (2015) Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression. Int J Epidemiol 44:512–525

Article  PubMed  PubMed Central  Google Scholar 

Bowden J, Davey Smith G, Haycock PC, Burgess S (2016) Consistent estimation in Mendelian randomization with some invalid instruments using a weighted median estimator. Genet Epidemiol 40:304–314

Article  PubMed  PubMed Central  Google Scholar 

Boyette LB, Macedo C, Hadi K, Elinoff BD, Walters JT, Ramaswami B, Chalasani G, Taboas JM, Lakkis FG, Metes DM (2017) Phenotype, function, and differentiation potential of human monocyte subsets. PLoS ONE 12:e0176460

Article  PubMed  PubMed Central  Google Scholar 

Bril V, England J, Franklin GM, Backonja M, Cohen J, del Toro D, Feldman E, Iverson DJ, Perkins B, Russell JW, Zochodne D (2011) Evidence-based guideline: treatment of painful diabetic neuropathy: report of the American academy of neurology, the American association of neuromuscular and electrodiagnostic medicine, and the American academy of physical medicine and rehabilitation. Neurology 76:1758–1765

Article  CAS  PubMed  PubMed Central  Google Scholar 

Carter AR, Sanderson E, Hammerton G, Richmond RC, Davey Smith G, Heron J, Taylor AE, Davies NM, Howe LD (2021) Mendelian randomisation for mediation analysis: current methods and challenges for implementation. Eur J Epidemiol 36:465–478

Article  PubMed  PubMed Central  Google Scholar 

Chen Y, Tang S (2023) Gut microbiota and immune mediation: a Mendelian randomization study on granulomatosis with polyangiitis. Front Immunol 14:1296016

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen X, Kong J, Diao X, Cai J, Zheng J, Xie W, Qin H, Huang J, Lin T (2020) Depression and prostate cancer risk: a Mendelian randomization study. Cancer Med 9:9160–9167

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cohen JL, Boyer O (2006) The role of CD4+CD25hi regulatory T cells in the physiopathogeny of graft-versus-host disease. Curr Opin Immunol 18:580–585

Article  CAS  PubMed  Google Scholar 

Colloca L, Ludman T, Bouhassira D, Baron R, Dickenson AH, Yarnitsky D, Freeman R, Truini A, Attal N, Finnerup NB, Eccleston C, Kalso E, Bennett DL, Dworkin RH, Raja SN (2017) Neuropathic pain. Nat Rev Dis Primers 3:17002

Article  PubMed  PubMed Central  Google Scholar 

Consensus workgroup on herpes zoster, C. D. A., National Clinical Research Center For Skin And Immune Diseases (2022) Chinese consensus on the diagnosis and management of herpes zoster (2022). Chin J Dermatol 55:1033–1040

Google Scholar 

Crișan TO, Cleophas MC, Oosting M, Lemmers H, Toenhake-Dijkstra H, Netea MG, Jansen TL, Joosten LA (2016) Soluble uric acid primes TLR-induced proinflammatory cytokine production by human primary cells via inhibition of IL-1Ra. Ann Rheum Dis 75:755–762

Article  PubMed  Google Scholar 

Daoub A, Ansari H, Orfanos G, Barnett A (2021) Rothia mucilaginosa: a case of septic arthritis in a native knee and review of the literature. BMJ Case Rep 14:e237015

Article  PubMed  PubMed Central  Google Scholar 

Defaye M, Gervason S, Altier C, Berthon JY, Ardid D, Filaire E, Carvalho FA (2020) Microbiota: a novel regulator of pain. J Neural Transm (vienna) 127:445–465

Article  CAS  PubMed  Google Scholar 

Dekker Nitert M, Mousa A, Barrett HL, Naderpoor N, De Courten B (2020) Altered gut microbiota composition is associated with back pain in overweight and obese individuals. Front Endocrinol (lausanne) 11:605

Article  PubMed  Google Scholar 

Ding W, You Z, Chen Q, Yang L, Doheny J, Zhou X, Li N, Wang S, Hu K, Chen L, Xia S, Wu X, Wang C, Zhang C, Chen L, Ritchie C, Huang P, Mao J, Shen S (2021) Gut microbiota influences neuropathic pain through modulating proinflammatory and anti-inflammatory T Cells. Anesth Analg 132:1146–1155

Article  CAS  PubMed  Google Scholar 

Dworkin RH, Backonja M, Rowbotham MC, Allen RR, Argoff CR, Bennett GJ, Bushnell MC, Farrar JT, Galer BS, Haythornthwaite JA, Hewitt DJ, Loeser JD, Max MB, Saltarelli M, Schmader KE, Stein C, Thompson D, Turk DC, Wallace MS, Watkins LR, Weinstein SM (2003) Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendations. Arch Neurol 60:1524–1534

Article  PubMed  Google Scholar 

Dworsky-Fried Z, Kerr BJ, Taylor AMW (2020) Microbes, microglia, and pain. Neurobiol Pain 7:100045

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fiore NT, Debs SR, Hayes JP, Duffy SS, Moalem-Taylor G (2023) Pain-resolving immune mechanisms in neuropathic pain. Nat Rev Neurol 19:199–220

PubMed  Google Scholar 

Fischer R, Proske M, Duffey M, Stangl H, Martinez GF, Peters N, Kraske A, Straub RH, Bethea JR, Kontermann RE, Pfizenmaier K (2018) Selective activation of tumor necrosis factor receptor II Induces antiinflammatory responses and alleviates experimental arthritis. Arthritis Rheumatol 70:722–735

Article  CAS  PubMed  Google Scholar 

Fischer R, Sendetski M, del Rivero T, Martinez GF, Bracchi-Ricard V, Swanson KA, Pruzinsky EK, Delguercio N, Rosalino MJ, Padutsch T, Kontermann RE, Pfizenmaier K, Bethea JR (2019) TNFR2 promotes Treg-mediated recovery from neuropathic pain across sexes. Proc Natl Acad Sci USA 116:17045–17050

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fiszer U, Mix E, Fredrikson S, Kostulas V, Link H (1994) Parkinson’s disease and immunological abnormalities: increase of HLA-DR expression on monocytes in cerebrospinal fluid and of CD45RO+ T cells in peripheral blood. Acta Neurol Scand 90:160–166

Article  CAS  PubMed  Google Scholar 

Getzenberg RB, Hijano DR, Hakim H, Dallas RH, Ferrolino JA, Van De Cardenas JB, Garner CD, Tang L, Su Y, Wolf J, Hayden RT, Maron G (2021) Rothia mucilaginosa infections in pediatric cancer patients. J Pediatric Infect Dis Soc 10:341–344

Article  PubMed  Google Scholar 

Gherghina ME, Peride I, Tiglis M, Neagu TP, Niculae A, Checherita IA (2022) Uric acid and oxidative stress-relationship with cardiovascular, metabolic, and renal impairment. Int J Mol Sci 23:3188

Article  CAS  PubMed  PubMed Central 

留言 (0)

沒有登入
gif