Kresge N, Simoni RD, Hill RL. Otto Fritz Meyerhof and the elucidation of the glycolytic pathway. J Biol Chem. 2005;280: e3.
Gamblin SJ, Cooper B, Millar JR, Davies GJ, Littlechild JA, Watson HC. The crystal structure of human muscle aldolase at 3.0 A resolution. FEBS Lett. 1990;262:282–6.
Cooper SJ, Leonard GA, McSweeney SM, et al. The crystal structure of a class II fructose-1,6-bisphosphate aldolase shows a novel binuclear metal-binding active site embedded in a familiar fold. Structure. 1996;4:1303–15.
Siebers B, Brinkmann H, Dorr C, et al. Archaeal fructose-1,6-bisphosphate aldolases constitute a new family of archaeal type class I aldolase. J Biol Chem. 2001;276:28710–8.
Thomson GJ, Howlett GJ, Ashcroft AE, Berry A. The dhnA gene of Escherichia coli encodes a class I fructose bisphosphate aldolase. Biochem J. 1998;331(Pt 2):437–45.
Article PubMed PubMed Central Google Scholar
Prasad CS, Gupta S, Kumar H, Tiwari M. Evolutionary and functional analysis of fructose bisphosphate aldolase of plant parasitic nematodes. Bioinformation. 2013;9:1–8.
Article PubMed PubMed Central Google Scholar
Plater AR, Zgiby SM, Thomson GJ, Qamar S, Wharton CW, Berry A. Conserved residues in the mechanism of the E. coli Class II FBP-aldolase. J Mol Biol. 1999;285:843–55.
Sauve V, Sygusch J. Molecular cloning, expression, purification, and characterization of fructose-1,6-bisphosphate aldolase from Thermus aquaticus. Protein Expr Purif. 2001;21:293–302.
Tolan DR, Niclas J, Bruce BD, Lebo RV. Evolutionary implications of the human aldolase-A, -B, -C, and -pseudogene chromosome locations. Am J Hum Genet. 1987;41:907–24.
PubMed PubMed Central Google Scholar
Arakaki TL, Pezza JA, Cronin MA, et al. Structure of human brain fructose 1,6-(bis)phosphate aldolase: linking isozyme structure with function. Protein Sci. 2004;13:3077–84.
Article PubMed PubMed Central Google Scholar
Kukita A, Yoshida MC, Fukushige S, et al. Molecular gene mapping of human aldolase A (ALDOA) gene to chromosome 16. Hum Genet. 1987;76:20–6.
Beutler E, Scott S, Bishop A, Margolis N, Matsumoto F, Kuhl W. Red cell aldolase deficiency and hemolytic anemia: a new syndrome. Trans Assoc Am Physicians. 1973;86:154–66.
Kishi H, Mukai T, Hirono A, Fujii H, Miwa S, Hori K. Human aldolase A deficiency associated with a hemolytic anemia: thermolabile aldolase due to a single base mutation. Proc Natl Acad Sci U S A. 1987;84:8623–7.
Article PubMed PubMed Central Google Scholar
Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71:209–49.
Schapira F, Dreyfus JC, Schapira G. Anomaly of aldolase in primary liver cancer. Nature. 1963;200:995–7.
Asaka M, Nagase K, Miyazaki T, Alpert E. Aldolase A isoenzyme levels in serum and tissues of patients with liver diseases. Gastroenterology. 1983;84:155–60.
Asaka M, Kimura T, Meguro T, et al. Alteration of aldolase isozymes in serum and tissues of patients with cancer and other diseases. J Clin Lab Anal. 1994;8:144–8.
Ojika T, Imaizumi M, Abe T, Kato K. Immunochemical and immunohistochemical studies on three aldolase isozymes in human lung cancer. Cancer. 1991;67:2153–8.
Mhawech-Fauceglia P, Wang D, Kesterson J, et al. Aldolase mRNA expression in endometrial cancer and the role of clotrimazole in endometrial cancer cell viability and morphology. Histopathology. 2011;59:1015–8.
Article PubMed PubMed Central Google Scholar
Jiang Z, Wang X, Li J, Yang H, Lin X. Aldolase A as a prognostic factor and mediator of progression via inducing epithelial-mesenchymal transition in gastric cancer. J Cell Mol Med. 2018;22:4377–86.
Article PubMed PubMed Central Google Scholar
Peng SY, Lai PL, Pan HW, Hsiao LP, Hsu HC. Aberrant expression of the glycolytic enzymes aldolase B and type II hexokinase in hepatocellular carcinoma are predictive markers for advanced stage, early recurrence and poor prognosis. Oncol Rep. 2008;19:1045–53.
Asaka M, Kimura T, Nishikawa S, Miyazuki T, Alpert E. Decreased serum aldolase B levels in patients with malignant tumors. Cancer. 1988;62:2554–7.
Lin J, Xia L, Oyang L, et al. The POU2F1-ALDOA axis promotes the proliferation and chemoresistance of colon cancer cells by enhancing glycolysis and the pentose phosphate pathway activity. Oncogene. 2022;41:1024–39.
Article PubMed PubMed Central Google Scholar
Tian W, Zhou J, Chen M, et al. Bioinformatics analysis of the role of aldolase A in tumor prognosis and immunity. Sci Rep. 2022;12:11632.
Article PubMed PubMed Central Google Scholar
Lu G, Shi W, Zhang Y. Prognostic implications and immune infiltration analysis of ALDOA in lung adenocarcinoma. Front Genet. 2021;12: 721021.
Article PubMed PubMed Central Google Scholar
Chang YC, Chan MH, Li CH, Chen CL, Tsai WC, Hsiao M. PPAR-gamma agonists reactivate the ALDOC-NR2F1 axis to enhance sensitivity to temozolomide and suppress glioblastoma progression. Cell Commun Signal. 2024;22:266.
Article PubMed PubMed Central Google Scholar
Peng C, Yang X, Li X, Ye Z, Wang J, Wu W. ALDOB plays a tumor-suppressive role by inhibiting AKT activation in gastric cancer. J Cancer. 2023;14:2255–62.
Article PubMed PubMed Central Google Scholar
Bu P, Chen KY, Xiang K, et al. Aldolase B-Mediated fructose metabolism drives metabolic reprogramming of colon cancer liver metastasis. Cell Metab. 2018;27(1249–62): e4.
Fan K, Wang J, Sun W, et al. MUC16 C-terminal binding with ALDOC disrupts the ability of ALDOC to sense glucose and promotes gallbladder carcinoma growth. Exp Cell Res. 2020;394: 112118.
Rose IA, O’Connell EL. Studies on the interaction of aldolase with substrate analogues. J Biol Chem. 1969;244:126–34.
Ye F, Chen Y, Xia L, Lian J, Yang S. Aldolase A overexpression is associated with poor prognosis and promotes tumor progression by the epithelial-mesenchymal transition in colon cancer. Biochem Biophys Res Commun. 2018;497:639–45.
Niu Y, Lin Z, Wan A, et al. Loss-of-function genetic screening identifies aldolase a as an essential driver for liver cancer cell growth under hypoxia. Hepatology. 2021;74:1461–79.
Shen Y, Xu J, Pan X, et al. LncRNA KCNQ1OT1 sponges miR-34c-5p to promote osteosarcoma growth via ALDOA enhanced aerobic glycolysis. Cell Death Dis. 2020;11:278.
Article PubMed PubMed Central Google Scholar
Chang YC, Chiou J, Yang YF, et al. Therapeutic targeting of aldolase a interactions inhibits lung cancer metastasis and prolongs survival. Cancer Res. 2019;79:4754–66.
Pan C, Li B, Simon MC. Moonlighting functions of metabolic enzymes and metabolites in cancer. Mol Cell. 2021;81:3760–74.
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