Moscat J, Karin M, Diaz-Meco MT (2016) p62 in cancer: signaling adaptor beyond autophagy. Cell 167(3):606–609

Article  PubMed  PubMed Central  Google Scholar 

Brandman O, Hegde RS (2016) Ribosome-associated protein quality control. Nat Struct Mol Biol 23(1):7–15

Article  PubMed  PubMed Central  Google Scholar 

Joazeiro CAP (2019) Mechanisms and functions of ribosome-associated protein quality control. Nat Rev Mol Cell Biol 20(6):368–383

Article  PubMed  PubMed Central  Google Scholar 

Sun Z, Brodsky JL (2019) Protein quality control in the secretory pathway. J Cell Biol 218(10):3171–3187

Article  PubMed  PubMed Central  Google Scholar 

Buchberger A, Bukau B, Sommer T (2010) Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms. Mol Cell 40(2):238–252

Article  PubMed  Google Scholar 

Bukau B, Weissman J, Horwich A (2006) Molecular chaperones and protein quality control. Cell 125(3):443–451

Article  PubMed  Google Scholar 

Marciniak SJ, Chambers JE, Ron D (2022) Pharmacological targeting of endoplasmic reticulum stress in disease. Nat Rev Drug Discov 21(2):115–140

Article  PubMed  Google Scholar 

Hwang J, Qi L (2018) Quality control in the endoplasmic reticulum: crosstalk between ERAD and UPR pathways. Trends Biochem Sci 43(8):593–605

Article  PubMed  PubMed Central  Google Scholar 

Lin MT, Beal MF (2006) Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443(7113):787–795

Article  PubMed  Google Scholar 

O’Malley J, Kumar R, Inigo J, Yadava N, Chandra D (2020) Mitochondrial stress response and cancer. Trends Cancer 6(8):688–701

Article  PubMed  PubMed Central  Google Scholar 

Wu W, Lin C, Wu K et al (2016) FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions. Embo J 35(13):1368–1384

Article  PubMed  PubMed Central  Google Scholar 

Liberek K, Lewandowska A, Zietkiewicz S (2008) Chaperones in control of protein disaggregation. Embo J 27(2):328–335

Article  PubMed  PubMed Central  Google Scholar 

Pohl C, Dikic I (2019) Cellular quality control by the ubiquitin-proteasome system and autophagy. Science 366(6467):818–822

Article  PubMed  Google Scholar 

Vargas JNS, Hamasaki M, Kawabata T, Youle RJ, Yoshimori T (2023) The mechanisms and roles of selective autophagy in mammals. Nat Rev Mol Cell Biol 24(3):167–185

Article  PubMed  Google Scholar 

Alberti S, Hyman AA (2021) Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing. Nat Rev Mol Cell Biol 22(3):196–213

Article  PubMed  Google Scholar 

Dikic I (2017) Proteasomal and autophagic degradation systems. Annu Rev Biochem 86:193–224

Article  PubMed  Google Scholar 

Mathieu C, Pappu RV, Taylor JP (2020) Beyond aggregation: pathological phase transitions in neurodegenerative disease. Science 370(6512):56–60

Article  PubMed  PubMed Central  Google Scholar 

Sun D, Wu R, Zheng J, Li P, Yu L (2018) Polyubiquitin chain-induced p62 phase separation drives autophagic cargo segregation. Cell Res 28(4):405–415

Article  PubMed  PubMed Central  Google Scholar 

Turco E, Savova A, Gere F et al (2021) Reconstitution defines the roles of p62, NBR1 and TAX1BP1 in ubiquitin condensate formation and autophagy initiation. Nat Commun 12(1):5212

Article  PubMed  PubMed Central  Google Scholar 

Gasset-Rosa F, Lu S, Yu H et al (2019) Cytoplasmic TDP-43 de-mixing independent of stress granules drives inhibition of nuclear import, loss of nuclear TDP-43, and cell death. Neuron 102(2):339-357.e337

Article  PubMed  PubMed Central  Google Scholar 

Wegmann S, Eftekharzadeh B, Tepper K et al (2018) Tau protein liquid-liquid phase separation can initiate tau aggregation. Embo J. https://doi.org/10.15252/embj.201798049

Article  PubMed  PubMed Central  Google Scholar 

Zhang G, Lin L, Qi D, Zhang H (2017) The composition of a protein aggregate modulates the specificity and efficiency of its autophagic degradation. Autophagy 13(9):1487–1495

Article  PubMed  PubMed Central  Google Scholar 

Ma X, Lu C, Chen Y et al (2022) CCT2 is an aggrephagy receptor for clearance of solid protein aggregates. Cell 185(8):1325-1345.e1322

Article  PubMed  Google Scholar 

Sriram SM, Kim BY, Kwon YT (2011) The N-end rule pathway: emerging functions and molecular principles of substrate recognition. Nat Rev Mol Cell Biol 12(11):735–747

Article  PubMed  Google Scholar 

Cha-Molstad H, Yu JE, Feng Z et al (2017) p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis. Nat Commun 8(1):102

Article  PubMed  PubMed Central  Google Scholar 

Peng H, Yang J, Li G et al (2017) Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress. Cell Res 27(5):657–674

Article  PubMed  PubMed Central  Google Scholar 

Wurzer B, Zaffagnini G, Fracchiolla D et al (2015) Oligomerization of p62 allows for selection of ubiquitinated cargo and isolation membrane during selective autophagy. Elife 4:e08941

Article  PubMed  PubMed Central  Google Scholar 

Ng MYW, Wai T, Simonsen A (2021) Quality control of the mitochondrion. Dev Cell 56(7):881–905

Article  PubMed  Google Scholar 

Leonhard K, Stiegler A, Neupert W, Langer T (1999) Chaperone-like activity of the AAA domain of the yeast Yme1 AAA protease. Nature 398(6725):348–351

Article  PubMed  Google Scholar 

Deshwal S, Fiedler KU, Langer T (2020) Mitochondrial proteases: multifaceted regulators of mitochondrial plasticity. Annu Rev Biochem 89:501–528

Article  PubMed  Google Scholar 

Jiao H, Jiang D, Hu X et al (2021) Mitocytosis, a migrasome-mediated mitochondrial quality-control process. Cell 184(11):2896-2910.e2813

Article  PubMed  Google Scholar 

Sugiura A, McLelland GL, Fon EA, McBride HM (2014) A new pathway for mitochondrial quality control: mitochondrial-derived vesicles. Embo J 33(19):2142–2156

Article  PubMed  PubMed Central  Google Scholar 

Izawa T, Park SH, Zhao L, Hartl FU, Neupert W (2017) Cytosolic protein Vms1 links ribosome quality control to mitochondrial and cellular homeostasis. Cell 171(4):890-903.e818

Article  PubMed  Google Scholar 

Sitron CS, Brandman O (2019) CAT tails drive degradation of stalled polypeptides on and off the ribosome. Nat Struct Mol Biol 26(6):450–459

Article  PubMed  PubMed Central