Werb Z, Chin JR. Extracellular matrix remodeling during morphogenesisa. Ann New York Acad Sci. 1998;857:110–8.

Article  Google Scholar 

Handsley MM, Edwards DR. Metalloproteinases and their inhibitors in tumor angiogenesis. Int J Cancer. 2005;115:849–60.

Article  PubMed  Google Scholar 

Vu TH, Werb Z. Matrix metalloproteinases: effectors of development and normal physiology. Genes Dev. 2000;14:2123–33.

Article  PubMed  Google Scholar 

Nelson AR, Fingleton B, Rothenberg ML, Matrisian LM. Matrix metalloproteinases: biologic activity and clinical implications. J Clin Oncol. 2000;18:1135–49.

Article  PubMed  Google Scholar 

Fini ME, Girard MT. Expression of collagenolytic/gelatinolytic metalloproteinases by normal cornea. Invest Ophthalmol Vis Sci. 1990;31:1779–88.

PubMed  Google Scholar 

Legrand C, Gilles C, Zahm JM, Polette M, Buisson AC, Kaplan H, et al. Airway epithelial cell migration dynamics: MMP-9 role in cell-extracellular matrix remodeling. J Cell Biol. 1999;146:517–29.

Article  PubMed  PubMed Central  Google Scholar 

Huang Q, Shen HM, Ong CN. Inhibitory effect of emodin on tumor invasion through suppression of activator protein-1 and nuclear factor-κB. Biochem Pharmacol. 2004;68:361–71.

Article  PubMed  Google Scholar 

Sato H, Seiki M. Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells. Oncogene. 1993;8:395–405.

PubMed  Google Scholar 

Ganguly K, Rejmak E, Mikosz M, Nikolaev E, Knapska E, Kaczmarek L. Matrix metalloproteinase (MMP) 9 transcription in mouse brain induced by fear learning. J Biol Chem. 2013;288:20978–91.

Article  PubMed  PubMed Central  Google Scholar 

Yurchenco P, Patton B. Developmental and pathogenic mechanisms of basement membrane assembly. Curr Pharm Des. 2009;15:1277–94.

Article  PubMed  PubMed Central  Google Scholar 

Breitkreutz D, Koxholt I, Thiemann K, Nischt R. Skin basement membrane: the foundation of epidermal integrity–BM functions and diverse roles of bridging molecules nidogen and perlecan. BioMed Res Int. 2013. https://doi.org/10.1155/2013/179784.

Article  PubMed  PubMed Central  Google Scholar 

Purwar R, Kraus M, Werfel T, Wittmann M. Modulation of keratinocyte-derived MMP-9 by IL-13: a possible role for the pathogenesis of epidermal inflammation. J Investig Dermatol. 2008;128:59–66.

Article  PubMed  Google Scholar 

Liu Z, Shipley JM, Vu TH, Zhou X, Diaz LA, Werb Z, et al. Gelatinase B–deficient mice are resistant to experimental bullous pemphigoid. J Exp Med. 1998;188:475–82.

Article  PubMed  PubMed Central  Google Scholar 

Kataoka H, Suganuma T, Shimomura T, Itoh H, Kitamura N, Nabeshima K, et al. Distribution of hepatocyte growth factor activator inhibitor type 1 (HAI-1) in human tissues Cellular surface localization of HAI-1 in simple columnar epithelium and its modulated expression in injured and regenerative tissues. J Histochem Cytochem Off J Histochem Soc. 1999;47:673–82.

Article  Google Scholar 

Tanaka H, Nagaike K, Takeda N, Itoh H, Kohama K, Fukushima T, et al. Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is required for branching morphogenesis in the chorioallantoic placenta. Mol Cell Biol. 2005;25:5687–98.

Article  PubMed  PubMed Central  Google Scholar 

Nagaike K, Kawaguchi M, Takeda N, Fukushima T, Sawaguchi A, Kohama K, et al. Defect of hepatocyte growth factor activator inhibitor type 1/serine protease inhibitor, Kunitz type 1 (Hai-1/Spint1) leads to ichthyosis-like condition and abnormal hair development in mice. Am J Pathol. 2008;173:1464–75.

Article  PubMed  PubMed Central  Google Scholar 

Kawaguchi M, Kanemaru A, Sawaguchi A, Yamamoto K, Baba T, Lin C-Y, et al. Hepatocyte growth factor activator inhibitor type 1 maintains the assembly of keratin into desmosomes in keratinocytes by regulating protease-activated receptor 2-dependent p38 signaling. Am J Pathol. 2015;185:1610–23.

Article  PubMed  PubMed Central  Google Scholar 

Fan B, Brennan J, Grant D, Peale F, Rangell L, Kirchhofer D. Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth. Dev Biol. 2007;303:222–30.

Article  PubMed  Google Scholar 

Kawaguchi M, Takeda N, Hoshiko S, Yorita K, Baba T, Sawaguchi A, et al. Membrane-bound serine protease inhibitor HAI-1 is required for maintenance of intestinal epithelial integrity. Am J Pathol. 2011;179:1815–26.

Article  PubMed  PubMed Central  Google Scholar 

Izumi A, Yamamoto K, Kawaguchi M, Yamashita F, Fukushima T, Kiwaki T, et al. Insufficiency of hepatocyte growth factor activator inhibitor-1 confers lymphatic invasion of tongue carcinoma cells. Cancer Sci. 2022;113:2179–93.

Article  PubMed  PubMed Central  Google Scholar 

Zhu P, Ren M, Yang C, Hu Y-X, Ran J-M, Yan L. Involvement of RAGE, MAPK and NF-κB pathways in AGEs-induced MMP-9 activation in HaCaT keratinocytes. Exp Dermatol. 2012;21:123–9.

Article  PubMed  Google Scholar 

Kawaguchi M, Yamamoto K, Kataoka H, Izumi A, Yamashita F, Kiwaki T, et al. PAR-2 accelerates intestinal tumor formation through activation of NF-κB signaling and tumor angiogenesis in Apc Min/+ mice. Cancer Sci. 2020;111:1193–202.

Article  PubMed  PubMed Central  Google Scholar 

Amano S, Ogura Y, Akutsu N, Matsunaga Y, Kadoya K, Adachi E, et al. Protective effect of matrix metalloproteinase inhibitors against epidermal basement membrane damage: skin equivalents partially mimic photoageing process. Br J Dermatol. 2005;153(Suppl 2):37–46.

Article  PubMed  Google Scholar 

Amano S, Akutsu N, Matsunaga Y, Kadoya K, Nishiyama T, Champliaud MF, et al. Importance of balance between extracellular matrix synthesis and degradation in basement membrane formation. Exp Cell Res. 2001;271:249–62.

Article  PubMed  Google Scholar 

Cheng H, Fukushima T, Takahashi N, Tanaka H, Kataoka H. Hepatocyte growth factor activator inhibitor type 1 regulates epithelial to mesenchymal transition through membrane-bound serine proteinases. Can Res. 2009;69:1828–35.

Article  Google Scholar 

Carney TJ, von der Hardt S, Sonntag C, Amsterdam A, Topczewski J, Hopkins N, et al. Inactivation of serine protease Matriptase1a by its inhibitor Hai1 is required for epithelial integrity of the zebrafish epidermis. Development. 2007;134:3461–71.

Article  PubMed  Google Scholar 

Mathias JR, Dodd ME, Walters KB, Rhodes J, Kanki JP, Look AT, et al. Live imaging of chronic inflammation caused by mutation of zebrafish Hai1. J Cell Sci. 2007;120:3372–83.

Article  PubMed  Google Scholar 

LeBert DC, Squirrell JM, Rindy J, Broadbridge E, Lui Y, Zakrzewska A, et al. Matrix metalloproteinase 9 modulates collagen matrices and wound repair. Dev (Cambridge). 2015;142:2136–46.

Article  Google Scholar 

Ogura Y, Matsunaga Y, Nishiyama T, Amano S. Plasmin induces degradation and dysfunction of laminin 332 (laminin 5) and impaired assembly of basement membrane at the dermal-epidermal junction. Br J Dermatol. 2008;159:49–60.

Article  PubMed  Google Scholar 

Amano S. Characterization and mechanisms of photoageing-related changes in skin damages of basement membrane and dermal structures. Exp Dermatol. 2016;25(Supl 3):14–9.

Article  PubMed  Google Scholar