Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71:209–49.

Article  PubMed  Google Scholar 

Olusola P, Banerjee HN, Philley JV, Dasgupta S. Human papilloma virus-associated cervical cancer and health disparities. Cells. 2019;8:622.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Drolet M, Benard E, Perez N, Brisson M, Group HPVVIS. Population-level impact and herd effects following the introduction of human papillomavirus vaccination programmes: updated systematic review and meta-analysis. Lancet. 2019;394:497–509.

Article  PubMed  PubMed Central  Google Scholar 

Chuang L, Koirala P, Nezhat F. Is it time to call for improvement in surgical techniques for minimally invasive radical hysterectomy? JSLS. 2020;24.

Liu H, Ye X, Li D, Yao Q, Li Y. Incidence, clinical risk and prognostic factors for liver metastasis in patients with cervical cancer: a population-based retrospective study. BMC Cancer. 2021;21:421.

Article  PubMed  PubMed Central  Google Scholar 

Xin T, Ding X, Gao H, Li C, Jiang Y, Chen X. Using Delphi method to develop Chinese women’s cervical cancer screening intention scale based on planned behavior theory. BMC Womens Health. 2022;22:512.

Article  PubMed  PubMed Central  Google Scholar 

Li H, Wu X, Cheng X. Advances in diagnosis and treatment of metastatic cervical cancer. J Gynecol Oncol. 2016;27: e43.

Article  PubMed  PubMed Central  Google Scholar 

Muthamilselvan S, Palaniappan A. CESCProg: a compact prognostic model and nomogram for cervical cancer based on miRNA biomarkers. PeerJ. 2023;11: e15912.

Article  PubMed  PubMed Central  Google Scholar 

Hsiao YH, Lin CW, Wang PH, Hsin MC, Yang SF. The potential of Chinese herbal medicines in the treatment of cervical cancer. Integr Cancer Ther. 2019;18:1534735419861693.

Article  PubMed  PubMed Central  Google Scholar 

Lin J, Chen L, Qiu X, Zhang N, Guo Q, Wang Y, et al. Traditional Chinese medicine for human papillomavirus (HPV) infections: A systematic review. Biosci Trends. 2017;11:267–73.

Article  PubMed  CAS  Google Scholar 

Cui T, Li BY, Liu F, Xiong L. research progress on sesquiterpenoids of curcumae rhizoma and their pharmacological effects. Biomolecules. 2024;14:387.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Li Z, Hao E, Cao R, Lin S, Zou L, Huang T, et al. Analysis on internal mechanism of zedoary turmeric in treatment of liver cancer based on pharmacodynamic substances and pharmacodynamic groups. Chin Herb Med. 2022;14:479–93.

PubMed  PubMed Central  CAS  Google Scholar 

Syed Abdul Rahman SN, Abdul Wahab N, Abd Malek SN. In vitro morphological assessment of apoptosis induced by antiproliferative constituents from the rhizomes of curcuma zedoaria. Evid Based Compl Alternat Med. 2013;2013: 257108.

Google Scholar 

Liao X, Li G, Cai R, Chen R. A review of emerging biomarkers for immune checkpoint inhibitors in tumors of the gastrointestinal tract. Med Sci Monit. 2022;28: e935348.

PubMed  PubMed Central  CAS  Google Scholar 

Chen X, Pan X, Zhang W, Guo H, Cheng S, He Q, et al. Epigenetic strategies synergize with PD-L1/PD-1 targeted cancer immunotherapies to enhance antitumor responses. Acta Pharm Sin B. 2020;10:723–33.

Article  PubMed  CAS  Google Scholar 

Santoro A, Angelico G, Inzani F, Arciuolo D, d’Amati A, Addante F, et al. The emerging and challenging role of PD-L1 in patients with gynecological cancers: An updating review with clinico-pathological considerations. Gynecol Oncol. 2024;184:57–66.

Article  PubMed  CAS  Google Scholar 

Yu S, Li L, Cai H, He B, Gao Y, Li Y. Overexpression of NELFE contributes to gastric cancer progression via Wnt/beta-catenin signaling-mediated activation of CSNK2B expression. J Exp Clin Cancer Res. 2021;40:54.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Wang W, Wang X, Li C, Chen T, Zhang N, Liang Y, et al. Huaier suppresses breast cancer progression via linc00339/miR-4656/CSNK2B signaling pathway. Front Oncol. 2019;9:1195.

Article  PubMed  PubMed Central  Google Scholar 

Yu S, Hu Q, Fan K, Yang C, Gao Y. CSNK2B contributes to colorectal cancer cell proliferation by activating the mTOR signaling. J Cell Commun Signal. 2021;15:383–92.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Xiao Y, Huang S, Qiu F, Ding X, Sun Y, Wei C, et al. Tumor necrosis factor alpha-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks nuclear factor-kappaB activation in hepatocellular carcinoma. EBioMedicine. 2020;51: 102603.

Article  PubMed  PubMed Central  Google Scholar 

Li N, Geng F, Liang SM, Qin X. USP7 inhibits TIMP2 by up-regulating the expression of EZH2 to activate the NF-kappaB/PD-L1 axis to promote the development of cervical cancer. Cell Signal. 2022;96: 110351.

Article  PubMed  CAS  Google Scholar 

Zheng T, Chen H. Anticancer effects of curzerenone against drug-resistant human lung carcinoma cells are mediated via programmed cell death, loss of mitochondrial membrane potential, ROS, and blocking the ERK/MAPK and NF-kappaB signaling pathway. J BUON. 2019;24:907–12.

PubMed  Google Scholar 

Gerard A, Khan O, Beemiller P, Oswald E, Hu J, Matloubian M, et al. Secondary T cell-T cell synaptic interactions drive the differentiation of protective CD8+ T cells. Nat Immunol. 2013;14:356–63.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Wang Q, Yen YT, Xie C, Liu F, Liu Q, Wei J, et al. Combined delivery of salinomycin and docetaxel by dual-targeting gelatinase nanoparticles effectively inhibits cervical cancer cells and cancer stem cells. Drug Deliv. 2021;28:510–9.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Varghese F, Bukhari AB, Malhotra R, De A. IHC Profiler: an open source plugin for the quantitative evaluation and automated scoring of immunohistochemistry images of human tissue samples. PLoS ONE. 2014;9: e96801.

Article  PubMed  PubMed Central  Google Scholar 

Han H, Wang L, Liu Y, Shi X, Zhang X, Li M, et al. Combination of curcuma zedoary and kelp inhibits growth and metastasis of liver cancer in vivo and in vitro via reducing endogenous H(2)S levels. Food Funct. 2019;10:224–34.

Article  PubMed  CAS  Google Scholar 

Wei W, Rasul A, Sadiqa A, Sarfraz I, Hussain G, Nageen B, et al. Curcumol: from plant roots to cancer roots. Int J Biol Sci. 2019;15:1600–9.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Mao Z, Zhong L, Zhuang X, Liu H, Peng Y. Curcumenol targeting YWHAG inhibits the pentose phosphate pathway and enhances antitumor effects of cisplatin. Evid Based Compl Alternat Med. 2022;2022:3988916.

Google Scholar 

Nickel J, Gohlke BO, Erehman J, Banerjee P, Rong WW, Goede A, et al. SuperPred: update on drug classification and target prediction. Nucleic Acids Res. 2014;42:W26-31.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Attwood MM, Jonsson J, Rask-Andersen M, Schioth HB. Soluble ligands as drug targets. Nat Rev Drug Discov. 2020;19:695–710.

Article  PubMed  CAS  Google Scholar 

Chen Y, Wang Y, Wang J, Zhou Z, Cao S, Zhang J. Strategies of targeting CK2 in drug discovery: challenges, opportunities, and emerging prospects. J Med Chem. 2023;66:2257–81.

Article  PubMed  CAS  Google Scholar 

Tilborghs S, Corthouts J, Verhoeven Y, Arias D, Rolfo C, Trinh XB, et al. The role of Nuclear Factor-kappa B signaling in human cervical cancer. Crit Rev Oncol Hematol. 2017;120:141–50.