Fujiwara Y, Arakawa T. Epidemiology and clinical characteristics of GERD in the Japanese population. J Gastroenterol. 2009;44:518–34. https://doi.org/10.1007/s00535-009-0047-5.
Iwakiri K, Fujiwara Y, Manabe N, et al. Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2021. J Gastroenterol. 2022;57:267–85. https://doi.org/10.1007/s00535-022-01861-z.
Article PubMed PubMed Central CAS Google Scholar
Fujiwara Y. Recent epidemiology of GERD in the Japanese population. Nihon Shokakibyo Gakkai Zasshi. 2017;114:1781–9. https://doi.org/10.11405/nisshoshi.114.1781.
Peery AF, Crockett SD, Murphy CC, et al. Burden and cost of gastrointestinal, liver, and pancreatic diseases in the united states: update 2021. Gastroenterology. 2022;162:621–44. https://doi.org/10.1053/j.gastro.2021.10.017.
Sawada A, Sifrim D, Fujiwara Y. Esophageal reflux hypersensitivity: a comprehensive review. Gut Liver. 2023;17:831–42. https://doi.org/10.5009/gnl220373.
Article PubMed PubMed Central CAS Google Scholar
Woodland P, Al-Zinaty M, Yazaki E, et al. In vivo evaluation of acid-induced changes in oesophageal mucosa integrity and sensitivity in non-erosive reflux disease. Gut. 2013;62:1256–61. https://doi.org/10.1136/gutjnl-2012-302645.
Norita K, Asanuma K, Koike T, et al. Impaired mucosal integrity in proximal esophagus is involved in development of proton pump inhibitor-refractory nonerosive reflux disease. Digestion. 2021;102:404–14. https://doi.org/10.1159/000508661.
Article PubMed CAS Google Scholar
Woodland P, Shen Ooi JL, Grassi F, et al. Superficial esophageal mucosal afferent nerves may contribute to reflux hypersensitivity in nonerosive reflux disease. Gastroenterology. 2017;153:1230–9. https://doi.org/10.1053/j.gastro.2017.07.017.
Sawada A, Zhang M, Ustaoglu A, et al. Superficial oesophageal mucosal innervation may contribute to severity of symptoms in oesophageal motility disorders. Aliment Pharmacol Ther. 2024;59:100–12. https://doi.org/10.1111/apt.17773.
Article PubMed CAS Google Scholar
Schey R, Dickman R, Parthasarathy S, et al. Sleep deprivation is hyperalgesic in patients with gastroesophageal reflux disease. Gastroenterology. 2007;133:1787–95. https://doi.org/10.1053/j.gastro.2007.09.039.
Fujiwara Y, Arakawa T, Fass R. Gastroesophageal reflux disease and sleep disturbances. J Gastroenterol. 2012;47:760–9. https://doi.org/10.1007/s00535-012-0601-4.
Article PubMed CAS Google Scholar
Hoshikawa Y, Momma E, Kawami N, et al. Lemborexant attenuates regurgitation without worsening objective parameters on reflux monitoring in patients with gastroesophageal reflux disease and insomnia: a single-arm proof-of-concept study. Digestion. 2023;104:438–45. https://doi.org/10.1159/000531412.
Article PubMed CAS Google Scholar
Okuyama M, Nakahara K, Iwakura N, et al. Factors associated with potassium-competitive acid blocker non-response in patients with proton pump inhibitor-refractory gastroesophageal reflux disease. Digestion. 2017;95:281–7. https://doi.org/10.1159/000475658.
Article PubMed CAS Google Scholar
Kessing BF, Bredenoord AJ, Saleh CM, et al. Effects of anxiety and depression in patients with gastroesophageal reflux disease. Clin Gastroenterol Hepatol : Off Clin Pract J Am Gastroenterol Assoc. 2015;13:1089-95.e1. https://doi.org/10.1016/j.cgh.2014.11.034.
Okuyama M, Takaishi O, Nakahara K, et al. Associations among gastroesophageal reflux disease, psychological stress, and sleep disturbances in Japanese adults. Scand J Gastroenterol. 2017;52:44–9. https://doi.org/10.1080/00365521.2016.1224383.
Article PubMed CAS Google Scholar
Taft TH, Triggs JR, Carlson DA, et al. Validation of the oesophageal hypervigilance and anxiety scale for chronic oesophageal disease. Aliment Pharmacol Ther. 2018;47:1270–7. https://doi.org/10.1111/apt.14605.
Article PubMed PubMed Central CAS Google Scholar
Hollins M, Walters S. Experimental hypervigilance changes the intensity/unpleasantness ratio of pressure sensations: evidence for the generalized hypervigilance hypothesis. Exp Brain Res. 2016;234:1377–84. https://doi.org/10.1007/s00221-015-4541-0.
Wong MW, Liu TT, Yi CH, et al. Oesophageal hypervigilance and visceral anxiety relate to reflux symptom severity and psychological distress but not to acid reflux parameters. Aliment Pharmacol Ther. 2021;54:923–30. https://doi.org/10.1111/apt.16561.
Guadagnoli L, Yadlapati R, Taft T, et al. Esophageal hypervigilance is prevalent across gastroesophageal reflux disease presentations. Neurogastroenterol Motil. 2021;33: e14081. https://doi.org/10.1111/nmo.14081.
Article PubMed PubMed Central CAS Google Scholar
Wong MW, Hsiao SH, Wang JH, et al. Esophageal hypervigilance and visceral anxiety contribute to symptom severity of laryngopharyngeal reflux. Am J Gastroenterol. 2023;118:786–93. https://doi.org/10.14309/ajg.0000000000002151.
Article PubMed CAS Google Scholar
Taft TH, Carlson DA, Simons M, et al. Esophageal hypervigilance and symptom-specific anxiety in patients with eosinophilic esophagitis. Gastroenterology. 2021;161:1133–44. https://doi.org/10.1053/j.gastro.2021.06.023.
Article PubMed CAS Google Scholar
Carlson DA, Gyawali CP, Roman S, et al. Esophageal hypervigilance and visceral anxiety are contributors to symptom severity among patients evaluated with high-resolution esophageal manometry. Am J Gastroenterol. 2020;115:367–75. https://doi.org/10.14309/ajg.0000000000000536.
Article PubMed PubMed Central Google Scholar
Nicodème F, de Ruigh A, Xiao Y, et al. A comparison of symptom severity and bolus retention with Chicago classification esophageal pressure topography metrics in patients with achalasia. Clin Gastroenterol Hepatol : Off Clin Pract J Am Gastroenterol Assoc. 2013. https://doi.org/10.1016/j.cgh.2012.10.015.
Guadagnoli L, Yadlapati R, Pandolfino J, et al. Behavioral therapy for functional heartburn: recommendation statements. Clin Gastroenterol Hepatol : Off Clin Pract J Am Gastroenterol Assoc. 2024;22(1709–18): e3. https://doi.org/10.1016/j.cgh.2024.03.004.
Eckardt VF, Aignherr C, Bernhard G. Predictors of outcome in patients with achalasia treated by pneumatic dilation. Gastroenterology. 1992;103:1732–8. https://doi.org/10.1016/0016-5085(92)91428-7.
Article PubMed CAS Google Scholar
Ponds FA, Fockens P, Lei A, et al. Effect of peroral endoscopic myotomy vs pneumatic dilation on symptom severity and treatment outcomes among treatment-naive patients with achalasia: a randomized clinical trial. JAMA. 2019;322:134–44. https://doi.org/10.1001/jama.2019.8859.
Article PubMed PubMed Central Google Scholar
Saleh CMG, Familiari P, Bastiaansen BAJ, et al. The efficacy of peroral endoscopic myotomy vs pneumatic dilation as treatment for patients with achalasia suffering from persistent or recurrent symptoms after laparoscopic heller myotomy: a randomized clinical trial. Gastroenterology. 2023;164(1108–18): e3. https://doi.org/10.1053/j.gastro.2023.02.048.
Suzuki H, Matsuzaki J, Okada S, et al. Validation of the GerdQ questionnaire for the management of gastro-oesophageal reflux disease in Japan. United European Gastroenterol J. 2013;1:175–83. https://doi.org/10.1177/2050640613485238.
Article PubMed PubMed Central Google Scholar
Jones R, Junghard O, Dent J, et al. Development of the GerdQ, a tool for the diagnosis and management of gastro-oesophageal reflux disease in primary care. Aliment Pharmacol Ther. 2009;30:1030–8. https://doi.org/10.1111/j.1365-2036.2009.04142.x.
留言 (0)