DeTure MA, Dickson DW. The neuropathological diagnosis of Alzheimer’s disease. Mol Neurodegener. 2019;14:32. https://doi.org/10.1186/s13024-019-0333-5.
Article PubMed PubMed Central Google Scholar
Spillantini MG, Schmidt ML, Lee VM-Y, Trojanowski JQ, Jakes R. Goedert, α-Synuclein in Lewy bodies. Nature. 1997;388:839–40. https://doi.org/10.1038/42166.
Article CAS PubMed Google Scholar
Hepp DH, Vergoossen DLE, Huisman E, Lemstra AW, Bank NB, Berendse HW, Rozemuller AJ, Foncke EMJ, Van De Berg WDJ. Distribution and load of amyloid-b pathology in Parkinson disease and dementia with lewy bodies. J Neuropathol Exp Neurol. 2016;75:936–45. https://doi.org/10.1093/jnen/nlw070.
Article CAS PubMed Google Scholar
Jellinger KA, Corey-Bloom J, Merdes AR, Hansen LA. Influence of Alzheimer pathology on clinical diagnostic accuracy in dementia with Lewy bodies [3] (multiple letters). Neurology. 2004;62:160. https://doi.org/10.1212/WNL.62.1.160.
Fujishiro H, Iseki E, Higashi S, Kasanuki K, Murayama N, Togo T, Katsuse O, Uchikado H, Aoki N, Kosaka K, Arai H, Sato K. Distribution of cerebral amyloid deposition and its relevance to clinical phenotype in Lewy body dementia. Neurosci Lett. 2010;486:19–23. https://doi.org/10.1016/j.neulet.2010.09.036.
Article CAS PubMed Google Scholar
Outeiro TF, Koss DJ, Erskine D, Walker L, Kurzawa-Akanbi M, Burn D, Donaghy P, Morris C, Taylor J-P, Thomas A, Attems J, McKeith I. Dementia with Lewy bodies: an update and outlook. Mol Neurodegener. 2019;14:5. https://doi.org/10.1186/s13024-019-0306-8.
Article PubMed PubMed Central Google Scholar
Golde TE, Miller VM. Proteinopathy-induced neuronal senescence: a hypothesis for brain failure in Alzheimer’s and other neurodegenerative diseases. Alzheimers Res Ther. 2009;1:5. https://doi.org/10.1186/alzrt5.
Article CAS PubMed PubMed Central Google Scholar
Hartl FU. Protein Misfolding Dis Annu Rev Biochem. 2017;86:21–6. https://doi.org/10.1146/annurev-biochem-061516-044518.
Sami N, Rahman S, Kumar V, Zaidi S, Islam A, Ali S, Ahmad F, Hassan MI. Protein aggregation, misfolding and consequential human neurodegenerative diseases. Int J Neurosci. 2017;127:1047–57. https://doi.org/10.1080/00207454.2017.1286339.
Article CAS PubMed Google Scholar
Lutz HU, Binder CJ, Kaveri S. Naturally occurring auto-antibodies in homeostasis and disease. Trends Immunol. 2009;30:43–51. https://doi.org/10.1016/j.it.2008.10.002.
Article CAS PubMed Google Scholar
Wu J, Li L. Autoantibodies in Alzheimer’s disease: potential biomarkers, pathogenic roles, and therapeutic implications. J Biomed Res. 2016;30:361–72. https://doi.org/10.7555/JBR.30.20150131.
Article CAS PubMed PubMed Central Google Scholar
Ciccocioppo F, Bologna G, Ercolino E, Pierdomenico L, Simeone P, Lanuti P, Pieragostino D, Del Boccio P, Marchisio M, Miscia S. Neurodegenerative diseases as proteinopathies-driven immune disorders. Neural Regen Res. 2020;15:850–6. https://doi.org/10.4103/1673-5374.268971.
Article CAS PubMed Google Scholar
Deleidi M, Maetzler W. Protein clearance mechanisms of alpha-synuclein and amyloid-Beta in lewy body disorders., Int. J. Alzheimers. Dis. 2012 (2012) 391438. https://doi.org/10.1155/2012/391438
Papuć E, Rejdak K. Anti-MAG autoantibodies are increased in Parkinson’s disease but not in atypical parkinsonism. J Neural Transm. 2017;124:209–16. https://doi.org/10.1007/s00702-016-1632-4.
Article CAS PubMed Google Scholar
Agrawal S, Abud EM, Snigdha S, Agrawal A. IgM response against amyloid-beta in aging: a potential peripheral protective mechanism. Alzheimers Res Ther. 2018;10:81. https://doi.org/10.1186/s13195-018-0412-9.
Article CAS PubMed PubMed Central Google Scholar
Brown EL, Essigmann HT, Hoffman KL, Alexander AS, Newmark M, Jiang Z-D, Suescun J, Schiess MC, Hanis CL, DuPont HL. IgA-Biome profiles correlate with clinical Parkinson’s Disease subtypes. J Parkinsons Dis. 2023;13:501–13. https://doi.org/10.3233/JPD-230066.
Article CAS PubMed PubMed Central Google Scholar
Pocevičiūtė D, Nuñez-Diaz C, Roth B, Janelidze S, Giannisis A, Hansson O, Wennström M, Bank TNB. Increased plasma and brain immunoglobulin A in Alzheimer’s disease is lost in apolipoprotein E ε4 carriers. Alzheimers Res Ther. 2022;14:117. https://doi.org/10.1186/s13195-022-01062-z.
Article CAS PubMed PubMed Central Google Scholar
Brudek T, Winge K, Folke J, Christensen S, Fog K, Pakkenberg B, Pedersen LØ. Autoimmune antibody decline in Parkinson’s disease and multiple system atrophy; a step towards immunotherapeutic strategies. Mol Neurodegener. 2017;12:44. https://doi.org/10.1186/s13024-017-0187-7.
Article CAS PubMed PubMed Central Google Scholar
Folke J, Rydbirk R, Løkkegaard A, Hejl A-M, Winge K, Starhof C, Salvesen L, Pedersen LØ, Aznar S, Pakkenberg B, Brudek T. Cerebrospinal fluid and plasma distribution of anti-α-synuclein IgMs and IgGs in multiple system atrophy and Parkinson’s disease. Parkinsonism Relat Disord. 2021;87:98–104. https://doi.org/10.1016/j.parkreldis.2021.05.001.
Article CAS PubMed Google Scholar
Folke J, Bergholt E, Pakkenberg B, Aznar S, Brudek T. Alpha-synuclein autoimmune decline in Prodromal multiple system atrophy and Parkinson’s Disease. Int J Mol Sci. 2022;23:6554. https://doi.org/10.3390/ijms23126554.
Article CAS PubMed PubMed Central Google Scholar
Jianping L, Zhibing Y, Wei Q, Zhikai C, Jie X, Jinbiao L. Low avidity and level of serum Anti-Aβ antibodies in Alzheimer Disease, Alzheimer dis. Assoc Disord 20 (2006). https://journals.lww.com/alzheimerjournal/Fulltext/2006/07000/Low_Avidity_and_Level_of_Serum_Anti_A__Antibodies.1.aspx
Folke J, Ferreira N, Brudek T, Borghammer P, Van Den Berge N. Passive Immunization in Alpha-Synuclein Preclinical Animal models. Biomolecules. 2022;12. https://doi.org/10.3390/biom12020168.
Sims JR, Zimmer JA, Evans CD, Lu M, Ardayfio P, Sparks J, Wessels AM, Shcherbinin S, Wang H, Monkul Nery ES, Collins EC, Solomon P, Salloway S, Apostolova LG, Hansson O, Ritchie C, Brooks DA, Mintun M, Skovronsky DM. 2 investigators, Donanemab in early symptomatic Alzheimer Disease: the TRAILBLAZER-ALZ 2 Randomized Clinical Trial. JAMA. 2023;330:512–27. https://doi.org/10.1001/jama.2023.13239.
Article CAS PubMed PubMed Central Google Scholar
Swanson CJ, Zhang Y, Dhadda S, Wang J, Kaplow J, Lai RYK, Lannfelt L, Bradley H, Rabe M, Koyama A, Reyderman L, Berry DA, Berry S, Gordon R, Kramer LD, Cummings JL. A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer’s disease with lecanemab, an anti-Aβ protofibril antibody. Alzheimers Res Ther. 2021;13:80. https://doi.org/10.1186/s13195-021-00813-8.
Article CAS PubMed PubMed Central Google Scholar
Postuma RB, Berg D, Stern M, Poewe W, Olanow CW, Oertel W, Obeso J, Marek K, Litvan I, Lang AE, Halliday G, Goetz CG, Gasser T, Dubois B, Chan P, Bloem BR, Adler CH, Deuschl G. MDS clinical diagnostic criteria for Parkinson’s disease. Mov Disord. 2015;30:1591–601. https://doi.org/10.1002/mds.26424.
Gilman S, Wenning GK, Low PA, Brooks DJ, Mathias CJ, Trojanowski JQ, Wood NW, Colosimo C, Dürr A, Fowler CJ, Kaufmann H, Klockgether T, Lees A, Poewe W, Quinn N, Revesz T, Robertson D, Sandroni P, Seppi K, Vidailhet M. Second consensus statement on the diagnosis of multiple system atrophy. Neurology. 2008;71:670–6. https://doi.org/10.1212/01.wnl.0000324625.00404.15.
Article CAS PubMed PubMed Central Google Scholar
McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor J-P, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, Bras J, Brundin P, Burn D, Chen-Plotkin A, Duda JE, El-Agnaf O, Feldman H, Ferman TJ, Ffytche D, Fujishiro H, Galasko D, Goldman JG, Gomperts SN, Graff-Radford NR, Honig LS, Iranzo A, Kantarci K, Kaufer D, Kukull W, Lee VMY, Leverenz JB, Lewis S, Lippa C, Lunde A, Masellis M, Masliah E, McLean P, Mollenhauer B, Montine TJ, Moreno E, Mori E, Murray M, O’Brien JT, Orimo S, Postuma RB, Ramaswamy S, Ross OA, Salmon DP, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo JB, Trojanowski JQ, Tsuang D, Walker Z, Yamada M, Kosaka K. Diagnosis and management of dementia with Lewy bodies: fourth consensus report of the DLB Consortium. Neurology. 2017;89:88–100. https://doi.org/10.1212/WNL.0000000000004058.
留言 (0)