Krisnawan VE, Stanley JA, Schwarz JK, DeNardo DG. Tumor Microenvironment as a Regulator of Radiation Therapy: New insights into stromal-mediated Radioresistance. Cancers (Basel). 2020;12(10).
Barker HE, Paget JT, Khan AA, Harrington KJ. The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence. Nat Rev Cancer. 2015;15(7):409–25.
Article CAS PubMed PubMed Central Google Scholar
Mathew AS, Atenafu EG, Owen D, Maurino C, Brade A, Brierley J, et al. Long term outcomes of stereotactic body radiation therapy for hepatocellular carcinoma without macrovascular invasion. Eur J Cancer. 2020;134:41–51.
Article CAS PubMed PubMed Central Google Scholar
Deng B, Zhao Z, Kong W, Han C, Shen X, Zhou C. Biological role of matrix stiffness in tumor growth and treatment. J Transl Med. 2022;20(1):540.
Article CAS PubMed PubMed Central Google Scholar
Pickup MW, Mouw JK, Weaver VM. The extracellular matrix modulates the hallmarks of cancer. EMBO Rep. 2014;15(12):1243–53.
Article CAS PubMed PubMed Central Google Scholar
Chen W, Yang A, Jia J, Popov YV, Schuppan D, You H. Lysyl Oxidase (LOX) family members: Rationale and their potential as therapeutic targets for liver fibrosis. Hepatology. 2020;72(2):729–41.
Article CAS PubMed Google Scholar
Roy AM, Iyer R, Chakraborty S. The extracellular matrix in hepatocellular carcinoma: mechanisms and therapeutic vulnerability. Cell Rep Med. 2023;4(9):101170.
Article CAS PubMed PubMed Central Google Scholar
Calitz C, Rosenquist J, Degerstedt O, Khaled J, Kopsida M, Fryknas M, et al. Influence of extracellular matrix composition on tumour cell behaviour in a biomimetic in vitro model for hepatocellular carcinoma. Sci Rep. 2023;13(1):748.
Article CAS PubMed PubMed Central Google Scholar
Liu SB, Ikenaga N, Peng ZW, Sverdlov DY, Greenstein A, Smith V, et al. Lysyl oxidase activity contributes to collagen stabilization during liver fibrosis progression and limits spontaneous fibrosis reversal in mice. FASEB J. 2016;30(4):1599–609.
Article CAS PubMed Google Scholar
Lewis S, Dawson L, Barry A, Stanescu T, Mohamad I, Hosni A. Stereotactic body radiation therapy for hepatocellular carcinoma: from infancy to ongoing maturity. JHEP Rep. 2022;4(8):100498.
Article PubMed PubMed Central Google Scholar
Valakh V, Gresswell S, Kirichenko A. Outcomes of Stereotactic Body Radiotherapy for Hepatocellular Carcinoma with severe cirrhosis and ineligibility for transplant. Anticancer Res. 2018;38(12):6815–20.
Article CAS PubMed Google Scholar
Kirichenko A, Uemura T, Liang Y, Hasan S, Abel S, Renz P, et al. Stereotactic body Radiation Therapy (SBRT) for Hepatocellular Carcinoma (HCC) with single Photon Emission Computed Tomography (SPECT) Functional Treatment Planning in patients with Advanced hepatic cirrhosis. Adv Radiat Oncol. 2024;9(2):101367.
Deng M, Lin J, Nowsheen S, Liu T, Zhao Y, Villalta PW et al. Extracellular matrix stiffness determines DNA repair efficiency and cellular sensitivity to genotoxic agents. Sci Adv. 2020;6(37).
Fischer RS, Myers KA, Gardel ML, Waterman CM. Stiffness-controlled three-dimensional extracellular matrices for high-resolution imaging of cell behavior. Nat Protoc. 2012;7(11):2056–66.
Article CAS PubMed Google Scholar
Lu SL, Chao PY, Liu WW, Han K, Cheng JC, Li PC. Longitudinal shear wave elasticity measurements of millimeter-sized biomaterials using a single-element transducer platform. PLoS ONE. 2022;17(4):e0266235.
Article CAS PubMed PubMed Central Google Scholar
Passaniti A, Kleinman HK, Martin GR. Matrigel: history/background, uses, and future applications. J Cell Commun Signal. 2022;16(4):621–6.
Article CAS PubMed Google Scholar
Lu SL, Liu WW, Cheng JC, Lin LC, Wang CC, Li PC. Enhanced radiosensitization for Cancer Treatment with Gold nanoparticles through Sonoporation. Int J Mol Sci. 2020;21:21.
Kuo LJ, Yang LX. Gamma-H2AX - a novel biomarker for DNA double-strand breaks. Vivo. 2008;22(3):305–9.
Jiang L, Tixeira R, Caruso S, Atkin-Smith GK, Baxter AA, Paone S, et al. Monitoring the progression of cell death and the disassembly of dying cells by flow cytometry. Nat Protoc. 2016;11(4):655–63.
Article CAS PubMed Google Scholar
Dong Y, Zheng Q, Wang Z, Lin X, You Y, Wu S, et al. Higher matrix stiffness as an independent initiator triggers epithelial-mesenchymal transition and facilitates HCC metastasis. J Hematol Oncol. 2019;12(1):112.
Article PubMed PubMed Central Google Scholar
Mueller S, Sandrin L. Liver stiffness: a novel parameter for the diagnosis of liver disease. Hepat Med. 2010;2:49–67.
PubMed PubMed Central Google Scholar
Yeh WC, Li PC, Jeng YM, Hsu HC, Kuo PL, Li ML, et al. Elastic modulus measurements of human liver and correlation with pathology. Ultrasound Med Biol. 2002;28(4):467–74.
Zembruski NC, Stache V, Haefeli WE, Weiss J. 7-Aminoactinomycin D for apoptosis staining in flow cytometry. Anal Biochem. 2012;429(1):79–81.
Article CAS PubMed Google Scholar
Deville SS, Cordes N. The Extracellular, Cellular, and Nuclear stiffness, a trinity in the Cancer Resistome-A Review. Front Oncol. 2019;9:1376.
Article PubMed PubMed Central Google Scholar
Schrader J, Gordon-Walker TT, Aucott RL, van Deemter M, Quaas A, Walsh S, et al. Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells. Hepatology. 2011;53(4):1192–205.
Article CAS PubMed Google Scholar
Liu C, Liu Y, Xie HG, Zhao S, Xu XX, Fan LX, et al. Role of three-dimensional matrix stiffness in regulating the chemoresistance of hepatocellular carcinoma cells. Biotechnol Appl Biochem. 2015;62(4):556–62.
Article CAS PubMed Google Scholar
Nguyen TV, Sleiman M, Moriarty T, Herrick WG, Peyton SR. Sorafenib resistance and JNK signaling in carcinoma during extracellular matrix stiffening. Biomaterials. 2014;35(22):5749–59.
Article CAS PubMed Google Scholar
Schulz A, Meyer F, Dubrovska A, Borgmann K. Cancer Stem cells and Radioresistance: DNA repair and Beyond. Cancers (Basel). 2019;11(6).
Subiel A, Ashmore R, Schettino G. Standards and methodologies for characterizing Radiobiological Impact of High-Z nanoparticles. Theranostics. 2016;6(10):1651–71.
Article CAS PubMed PubMed Central Google Scholar
Gomez-Roman N, Stevenson K, Gilmour L, Hamilton G, Chalmers AJ. A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses. Neuro Oncol. 2017;19(2):229–41.
Hehlgans S, Lange I, Eke I, Cordes N. 3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226. Radiother Oncol. 2009;92(3):371–8.
Article CAS PubMed Google Scholar
Wegge M, Dok R, Dubois LJ, Nuyts S. Use of 3D spheroid models for the Assessment of RT response in Head and Neck Cancer. Int J Mol Sci. 2023;24(4).
Maeda J, Froning CE, Brents CA, Rose BJ, Thamm DH, Kato TA. Intrinsic Radiosensitivity and Cellular characterization of 27 Canine Cancer Cell lines. PLoS ONE. 2016;11(6):e0156689.
Article PubMed PubMed Central Google Scholar
Chung EJ, Brown AP, Asano H, Mandler M, Burgan WE, Carter D, et al. In vitro and in vivo radiosensitization with AZD6244 (ARRY-142886), an inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 kinase. Clin Cancer Res. 2009;15(9):3050–7.
留言 (0)