Eder, J., Sedrani, R. & Wiesmann, C. The discovery of first-in-class drugs: origins and evolution. Nat. Rev. Drug Discov. 13, 577–587 (2014).
Article CAS PubMed Google Scholar
Hopkins, A. L., Keserü, G. M., Leeson, P. D., Rees, D. C. & Reynolds, C. H. The role of ligand efficiency metrics in drug discovery. Nat. Rev. Drug Discov. 13, 105–121 (2014).
Article CAS PubMed Google Scholar
Vitaku, E., Smith, D. T. & Njardarson, J. T. Analysis of the structural diversity, substitution patterns, and frequency of nitrogen heterocycles among US FDA approved pharmaceuticals. J. Med. Chem. 57, 10257–10274 (2014).
Article CAS PubMed Google Scholar
Rotella, D. P. in Advances in Heterocyclic Chemistry vol. 134 (eds Meanwell, N. A. & Lolli, M. L.) 149–183 (Academic Press, 2021).
Kabir, E. & Uzzaman, M. A review on biological and medicinal impact of heterocyclic compounds. Res. Chem. 4, 100606 (2022).
Gomtsyan, A. Heterocycles in drugs and drug discovery. Chem. Het. Comp. 48, 7–10 (2012).
Heravi, M. M. & Zadsirjan, V. Prescribed drugs containing nitrogen heterocycles: an overview. RSC Adv. 10, 44247–44311 (2020).
Article CAS PubMed PubMed Central Google Scholar
Estévez, V., Villacampa, M. & Menéndez, J. C. Multicomponent reactions for the synthesis of pyrroles. Chem. Soc. Rev. 39, 4402–4421 (2010).
Hill, M. D. Recent strategies for the synthesis of pyridine derivatives. Chem. Eur. J. 16, 12052–12062 (2010).
Article CAS PubMed Google Scholar
Marco-Contelles, J., Pérez-Mayoral, E., Samadi, A., Carreiras, M. d. C. & Soriano, E. Recent advances in the Friedländer reaction. Chem. Rev. 109, 2652–2671 (2009).
Article CAS PubMed Google Scholar
Ran, L., Ren, Z.-H., Wang, Y.-Y. & Guan, Z.-H. Copper-catalyzed homocoupling of ketoxime carboxylates for synthesis of symmetrical pyrroles. Green. Chem. 16, 112–115 (2014).
Wang, Y., Zhang, W.-X. & Xi, Z. Carbodiimide-based synthesis of N-heterocycles: moving from two classical reactive sites to chemical bond breaking/forming reaction. Chem. Soc. Rev. 49, 5810–5849 (2020).
Tamatam, R. & Shin, D. Recent advances in the transition-metal-free synthesis of quinazolines. Molecules 28, 3227 (2023).
Article CAS PubMed PubMed Central Google Scholar
Horváth, I. T. Introduction: sustainable chemistry. Chem. Rev. 118, 369–371 (2018).
Huber, G. W., Iborra, S. & Corma, A. Synthesis of transportation fuels from biomass: chemistry, catalysts, and engineering. Chem. Rev. 106, 4044–4098 (2006).
Article CAS PubMed Google Scholar
Besson, M., Gallezot, P. & Pinel, C. Conversion of biomass into chemicals over metal catalysts. Chem. Rev. 114, 1827–1870 (2014).
Article CAS PubMed Google Scholar
Luk, H. T., Mondelli, C., Ferré, D. C., Stewart, J. A. & Pérez-Ramírez, J. Status and prospects in higher alcohols synthesis from syngas. Chem. Soc. Rev. 46, 1358–1426 (2017).
Article CAS PubMed Google Scholar
Alonso, D. M., Bond, J. Q. & Dumesic, J. A. Catalytic conversion of biomass to biofuels. Green. Chem. 12, 1493–1513 (2010).
Vispute, T. P., Zhang, H., Sanna, A., Xiao, R. & Huber, G. W. Renewable chemical commodity feedstocks from integrated catalytic processing of pyrolysis oils. Science 330, 1222–1227 (2010).
Article CAS PubMed Google Scholar
Gunanathan, C. & Milstein, D. Applications of acceptorless dehydrogenation and related transformations in chemical synthesis. Science 341, 1229712 (2013).
Subaramanian, M., Sivakumar, G. & Balaraman, E. First-row transition-metal catalyzed acceptorless dehydrogenation and related reactions: a personal account. Chem. Rec. 21, 3839–3871 (2021).
Article CAS PubMed Google Scholar
Mondal, A., Sharma, R., Pal, D. & Srimani, D. Recent progress in the synthesis of heterocycles through base Metal-Catalyzed acceptorless dehydrogenative and borrowing hydrogen approach. Eur. J. Org. Chem. 2021, 3690–3720 (2021).
Dobereiner, G. E. & Crabtree, R. H. Dehydrogenation as a substrate-activating strategy in homogeneous transition-metal catalysis. Chem. Rev. 110, 681–703 (2010).
Article CAS PubMed Google Scholar
Paul, B., Maji, M., Chakrabarti, K. & Kundu, S. Tandem transformations and multicomponent reactions utilizing alcohols following dehydrogenation strategy. Org. Biomol. Chem. 18, 2193–2214 (2020).
Article CAS PubMed Google Scholar
Roy, B. C., Ganguli, K., Samim, S. A. & Kundu, S. Alkyl phosphine free, metal-ligand cooperative complex catalyzed alcohol dehydrogenative coupling reactions. Asian J. Org. Chem. 10, 1218–1232 (2021).
Michlik, S. & Kempe, R. A sustainable catalytic pyrrole synthesis. Nat. Chem. 5, 140–144 (2013).
Article CAS PubMed Google Scholar
Maji, M., Panja, D., Borthakur, I. & Kundu, S. Recent advances in sustainable synthesis of N-heterocycles following acceptorless dehydrogenative coupling protocol using alcohols. Org. Chem. Front. 8, 2673–2709 (2021).
Sun, K., Shan, H., Lu, G.-P., Cai, C. & Beller, M. Synthesis of N-heterocycles via oxidant-free dehydrocyclization of alcohols using heterogeneous catalysts. Angew. Chem. Int. Ed. 60, 25188–25202 (2021).
Mukherjee, A. & Milstein, D. Homogeneous catalysis by cobalt and manganese pincer complexes. ACS Catal. 8, 11435–11469 (2018).
Mastalir, M., Glatz, M., Pittenauer, E., Allmaier, G. & Kirchner, K. Sustainable synthesis of quinolines and pyrimidines catalyzed by manganese PNP pincer complexes. J. Am. Chem. Soc. 138, 15543–15546 (2016).
Article CAS PubMed Google Scholar
Sun, K., Li, D., Lu, G.-P. & Cai, C. Hydrogen auto-transfer synthesis of quinoxalines from o-nitroanilines and biomass-based diols catalyzed by MOF-derived N,P Co-doped cobalt catalysts. ChemCatChem 13, 373–381 (2021).
Su, T., Sun, K., Lu, G. & Cai, C. Synthesis of quinazolinones via a tandem hydrogen-transfer strategy catalyzed by N,S Co-doped carbon-anchored Co nanoparticles. ACS Sustain. Chem. Eng. 10, 3872–3881 (2022).
Wang, F. et al. KOtBu-mediated transition-metal-free synthesis of pyrimidines by selective three-component coupling reactions: a mechanistic insight. Tetrahedron 123, 132985 (2022).
Maji, M., Borthakur, I., Guria, S., Singha, S. & Kundu, S. Direct access to 2-(N-alkylamino)pyrimidines via ruthenium catalyzed tandem multicomponent annulation/N-alkylation. J. Catal. 402, 37–51 (2021).
Maji, M., Chakrabarti, K., Panja, D. & Kundu, S. Sustainable synthesis of N-heterocycles in water using alcohols following the double dehydrogenation strategy. J. Catal. 373, 93–102 (2019).
留言 (0)