Chemical Implications of apo-8, 6’ Carotendial versus Intact Lycopene on Mechanism of Enhanced Cell-cell Communication and Apoptosis Induction in Breast Cancer Cells

Arathi, B. P., Sowmya, P. R., Vijay, K., Baskaran, V., & Lakshminarayana, R. (2015). Metabolomics of carotenoids: The challenges and prospects-A review. Trends in Food Science and Technology, 45, 105–117. https://doi.org/10.1016/j.tifs.2015.06.003.

Article  CAS  Google Scholar 

Raju M., Sowmya P. R., Ambedkar R., Arathi B. P., Lakshminarayana R. (2021) Carotenoid metabolic pathways and their functional role in health and diseases. In: Global Perspectives on Astaxanthin. Elsevier. 671–691. https://doi.org/10.1016/B978-0-12-823304-7.00034-9.

Lakshminarayana R., Paul B. (2022) Free radical chemistry of carotenoids and oxidative stress physiology of cancer. In: Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. 1–22 https://doi.org/10.1007/978-981-16-1247-3_262-1.

Lakshminarayana, R., Aruna, G., Sangeetha, R. K., Bhaskar, N., Divakar, S., & Baskaran, V. (2008). Possible degradation/biotransformation of lutein in vitro and in vivo: isolation and structural elucidation of lutein metabolites by HPLC and LC-MS (atmospheric pressure chemical ionization). Free Radical Biology and Medicine, 45, 982–993. https://doi.org/10.1016/j.freeradbiomed.2008.06.011.

Article  CAS  PubMed  Google Scholar 

Lakshminarayana, R., Aruna, G., Sathisha, U. V., Dharmesh, S. M., & Baskaran, V. (2013). Structural elucidation of possible lutein oxidation products mediated through peroxyl radical inducer 2, 2′-Azobis (2-methylpropionamidine) dihydrochloride: Antioxidant and cytotoxic influence of oxidized lutein in HeLa cells. Chemico-Biological Interactions, 203, 448–455. https://doi.org/10.1016/j.cbi.2013.03.006.

Article  CAS  PubMed  Google Scholar 

Arathi, B. P., Sowmya, P. R., Kuriakose, G. C., Vijay, K., Baskaran, V., Jayabaskaran, C., & Lakshminarayana, R. (2016). Enhanced cytotoxic and apoptosis inducing activity of lycopene oxidation products in different cancer cell lines. Food and Chemical Toxicology, 97, 265–276. https://doi.org/10.1016/j.fct.2016.09.016.

Article  CAS  PubMed  Google Scholar 

Arathi, B. P., Sowmya, P. R., Kuriakose, G. C., Shilpa, S., Shwetha, H. J., Kumar, S., Raju, M., Baskaran, V., & Lakshminarayana, R. (2018). Fractionation and characterization of lycopene-oxidation products by LC-MS/MS (ESI)+: Elucidation of the chemopreventative potency of oxidized lycopene in breast-cancer cell lines. Journal of Agricultural and Food Chemistry, 66, 11362–11371. https://doi.org/10.1021/acs.jafc.8b04850.

Article  CAS  PubMed  Google Scholar 

Hanusch, M., Stahl, W., Schulz, W. A., & Sies, H. (1995). Induction of Gap Junctional Communication by 4-Oxoretinoic Acid Generated from Its Precursor Canthaxanthin. Archives of Biochemistry and Biophysics, 317, 423–428. https://doi.org/10.1006/abbi.1995.1184.

Article  CAS  PubMed  Google Scholar 

King, T. J., Khachik, F., Bortkiewicz, H., Fukushima, L. H., Morioka, S., & Bertram, J. S. (1997). Metabolites of dietary carotenoids as potential cancer preventive agents. Pure and Applied Chemistry, 69, 2135–2140. https://doi.org/10.1351/pac199769102135.

Article  CAS  Google Scholar 

Khachik, F., Spangler, C. J., Smith, J. C., Canfield, L. M., Steck, A., & Pfander, H. (1997). Identification, quantification, and relative concentrations of carotenoids and their metabolites in human milk and serum. Analytical Chemistry, 69, 1873–1881. https://doi.org/10.1021/ac961085i.

Article  CAS  PubMed  Google Scholar 

Hu, K. Q., Liu, C., Ernst, H., Krinsky, N. I., Russell, R. M., & Wang, X. D. (2006). The biochemical characterization of ferret carotene-9’,10’-monooxygenase catalyzing cleavage of carotenoids in vitro and in vivo. Journal of Biological Chemistry, 281, 19327–19338.

Article  CAS  PubMed  Google Scholar 

Duitsman, P. K., Barua, A. B., Becker, B., & Olson, J. A. (1999). Effects of epoxycarotenoids, beta-carotene, and retinoic acid on the differentiation and viability of the leukemia cell line NB4 in vitro. International Journal for Vitamin and Nutrition Research, 69, 303–308. https://doi.org/10.1024/0300-9831.69.5.303.

Article  CAS  PubMed  Google Scholar 

Zhang, H., Kotake-Nara, E., Ono, H., & Nagao, A. (2003). A Novel cleavage product formed by autoxidation of lycopene induces apoptosis in HL-60 cells. Free Radical Biology and Medicine, 35, 1653–1663. https://doi.org/10.1016/J.FREERADBIOMED.2003.09.019.

Article  CAS  PubMed  Google Scholar 

Wang, X. D. (2012). Lycopene metabolism and its biological significance. The American Journal of Clinical Nutrition, 96, 1214S–1222S. https://doi.org/10.3945/ajcn.111.032359.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Khachik, F., Pfander, H., & Traber, B. (1998). Proposed mechanisms for the formation of synthetic and naturally occurring metabolites of lycopene in tomato products and human serum. Journal of Agricultural and Food Chemistry, 46, 4885–4890. https://doi.org/10.1021/jf9803233.

Article  CAS  Google Scholar 

Kim, S. J., Nara, E., Kobayashi, H., Terao, J., & Nagao, A. (2001). Formation of cleavage products by autoxidation of lycopene. Lipids, 36, 191–200. https://doi.org/10.1007/s11745-001-0706-8.

Article  CAS  PubMed  Google Scholar 

Caris-Veyrat, C., Schmid, A., Carail, M., & Böhm, V. (2003). Cleavage products of lycopene produced by in vitro oxidations: characterization and mechanisms of formation. Journal of Agricultural and Food Chemistry, 51, 7318–7325. https://doi.org/10.1021/jf034735.

Article  CAS  PubMed  Google Scholar 

Lucia dos Anjos Ferreira, A., Yeum, K. J., Russell, R. M., Krinsky, N. I., & Tang, G. (2004). Enzymatic and oxidative metabolites of lycopene. Journal of Nutritional Biochemistry, 15, 493–502. https://doi.org/10.1016/j.jnutbio.2004.02.007.

Article  CAS  Google Scholar 

Gajic, M., Zaripheh, S., Sun, F., & Erdman, J. W. (2006). Apo-8′-lycopenal and apo-12′-lycopenal are metabolic products of lycopene in rat liver. Journal of Nutrition, 136, 1552–1557. https://doi.org/10.1093/jn/136.6.1552.

Article  CAS  PubMed  Google Scholar 

Rodriguez, E. B., & Rodriguez-Amaya, D. B. (2009). Lycopene epoxides and apo-lycopenals formed by chemical reactions and autoxidation in model systems and processed foods. Journal of Food Science, 74, C674–C682. https://doi.org/10.1111/j.1750-3841.2009.01353.x.

Article  CAS  PubMed  Google Scholar 

Cichon, M. J., Moran, N. E., Riedl, K. M., Schwartz, S. J., & Clinton, S. K. (2018). Identification of an epoxide metabolite of lycopene in human plasma using 13C-labeling and QTOF-MS. Metabolites, 8(1), 20–24.

Article  Google Scholar 

Kopec, R. E., Riedl, K. M., Harrison, E. H., Curley, R. W., Hruszkewycz, D. P., Clinton, S. K., & Schwartz, S. J. (2010). Identification and quantification of apo-lycopenals in fruits, vegetables, and human plasma. Journal of Agricultural and Food Chemistry, 58, 3290–3296. https://doi.org/10.1021/jf100415z.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sowmya, P. R., Arathi, B. P., Vijay, K., Baskaran, V., & Lakshminarayana, R. (2017). Astaxanthin from shrimp efficiently modulates oxidative stress and allied cell death progression in MCF-7 cells treated synergistically with β-carotene and lutein from greens. Food and Chemical Toxicology, 106, 58–69. https://doi.org/10.1016/j.fct.2017.05.024.

Article  CAS  PubMed  Google Scholar 

Liang, C. C., Park, A. Y., & Guan, J. L. (2007). In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nature Protocols, 2, 329–333. https://doi.org/10.1038/nprot.2007.30.

Article  CAS  PubMed  Google Scholar 

Sowmya, P. R., Arathi, B. P., Vijay, K., Baskaran, V., & Lakshminarayana, R. (2015). Role of different vehicles in carotenoids delivery and their influence on cell viability, cell cycle progression, and induction of apoptosis in HeLa cells. Molecular and Cellular Biochemistry, 406, 245–253. https://doi.org/10.1007/s11010-015-2442-y.

Article  CAS  PubMed  Google Scholar 

Yeh, S. L., & Hu, M. L. (2003). Oxidized β-carotene inhibits gap junction intercellular communication in the human lung adenocarcinoma cell line A549. Food and Chemical Toxicology, 41, 1677–1684. https://doi.org/10.1016/S0278-6915(03)00192-3.

Article  CAS  PubMed  Google Scholar 

Chalabi, N., le Corre, L., Maurizis, J. C., Bignon, Y. J., & Bernard-Gallon, D. J. (2004). The effects of lycopene on the proliferation of human breast cells and BRCA1 and BRCA2 gene expression. European Journal of Cancer, 40, 1768–1775. https://doi.org/10.1016/j.ejca.2004.03.028.

Article  CAS  PubMed  Google Scholar 

Guo, R., Liu, L., & Barajas, L. (1998). RT-PCR study of the distribution of connexin 43 mRNA in the glomerulus and renal tubular segments. American Journal of Physiology, 275, R439–R447. https://doi.org/10.1152/ajpregu.1998.275.2.R439.

Article  CAS  PubMed 

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