Effect of Xanthohumol from Humulus lupulus L. Against Gouty Bone Damage in Arthritis of Rats Induced by Mono-sodium Urate

Huddleston, E. M., & Gaffo, A. L. (2022). Emerging strategies for treating gout. Current Opinion in Pharmacology, 65, 102241. https://doi.org/10.1016/j.coph.2022.102241.

Article  CAS  PubMed  Google Scholar 

Singh, J. A., & Gaffo, A. (2020). Gout epidemiology and comorbidities. Seminars in Arthritis and Rheumatism, 50, S11–S16. https://doi.org/10.1016/j.semarthrit.2020.04.008.

Article  PubMed  Google Scholar 

Feng, W., & Xiong, G. (2021). Clinical classification and treatment experience of wrist gouty arthritis. Chinese Journal of Reparative and Reconstructive Surgery, 35, 1411–1416. https://doi.org/10.7507/1002-1892.202103043.

Article  PubMed  Google Scholar 

Gelber, A. C.(2022). Treatment guidelines in gout. Rheumatic Disease Clinics of North America, 48, 659–678. https://doi.org/10.1016/j.rdc.2022.04.003.

Article  PubMed  Google Scholar 

Blake, K. E. G., Saag, J. L., & Saag, K. G. (2022). What’s new on the front-line of gout pharmacotherapy?. Expert Opinion on Pharmacotherapy, 23, 453–464. https://doi.org/10.1080/14656566.2021.2020249.

Article  CAS  PubMed  Google Scholar 

Bafna, P. S., Patil, P. H., Maru, S. K., & Mutha, R. E. (2021). Cissus quadrangularis L: A comprehensive multidisciplinary review. Journal of Ethnopharmacology, 279, 114355. https://doi.org/10.1016/j.jep.2021.114355.

Article  CAS  PubMed  Google Scholar 

Al Mamun, M. A., Hosen, M. J., & Islam, K. et al.(2015). Tridax procumbens flavonoids promote osteoblast differentiation and bone formation. Biological Research, 48, 65. https://doi.org/10.1186/s40659-015-0056-1.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Al Mamun, M. A., Islam, K., & Alam, M. J. et al.(2015). Flavonoids isolated from Tridax procumbens (TPF) inhibit osteoclasts differentiation and bone resorption. Biological Research, 48, 51. https://doi.org/10.1186/s40659-015-0043-6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Feng, W., Zhong, X. Q., & Zheng, X. X. et al.(2022). Study on the effect and mechanism of quercetin in treating gout arthritis. International Immunopharmacology, 111, 109112. https://doi.org/10.1016/j.intimp.2022.109112.

Article  CAS  PubMed  Google Scholar 

Qiao, C. Y., Li, Y., & Shang, Y., et al. (2020). Management of Gout-associated MSU crystals-induced NLRP3 inflammasome activation by procyanidin B2: targeting IL-1β and Cathepsin B in macrophages. Inflammopharmacology, 28, 1481–1493. https://doi.org/10.1007/s10787-020-00758-8.

Article  CAS  PubMed  Google Scholar 

Zhao, Z., Luo, J., & Liao, H. et al.(2023). Pharmacological evaluation of a novel skeleton compound isobavachin (4’,7-dihydroxy-8-prenylflavanone) as a hypouricemic agent: Dual actions of URAT1/GLUT9 and xanthine oxidase inhibitory activity. Bioorganic Chemistry, 133, 106405. https://doi.org/10.1016/j.bioorg.2023.106405.

Article  CAS  PubMed  Google Scholar 

Aggarwal, D., Upadhyay, S. K., Singh, R., & Tuli, H. S. (2021). Recent patents on therapeutic activities of xanthohumol: a prenylated chalconoid from hops (Humulus lupulus L). Pharmaceutical Patent Analyst, 10, 37–49. https://doi.org/10.4155/ppa-2020-0026.

Vicente de Andrade Silva, G., Demaman Arend, G., & Antonio Ferreira Zielinski, A., et al. (2023). Xanthohumol properties and strategies for extraction from hops and brewery residues: A review. Food Chemistry, 404, 134629. https://doi.org/10.1016/j.foodchem.2022.134629.

Article  CAS  PubMed  Google Scholar 

Deng, P., Wang, S., & Sun, X. et al.(2022). Global trends in research of gouty arthritis over past decade: A bibliometric analysis. Frontiers in Immunology, 13, 910400. https://doi.org/10.3389/fimmu.2022.910400.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu, M., Hansen, P. E., & Wang, G., et al. (2015). Pharmacological profile of xanthohumol, a prenylated flavonoid from hops (Humulus lupulus L.). Molecules, 20, 754–779. https://doi.org/10.3390/molecules20010754.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tuli, H. S., Aggarwal, V., & Parashar, G. et al.(2022). Xanthohumol: A metabolite with promising anti-neoplastic potential. Anti-Cancer Agents in Medicinal Chemistry, 22, 418–432. https://doi.org/10.2174/1871520621666210223095021.

Article  CAS  PubMed  Google Scholar 

van Breemen, R. B., Yuan, Y., & Banuvar, S. et al.(2014). Pharmacokinetics of prenylated hop phenols in women following oral administration of a standardized extract of hops. Molecular Nutrition & Food Research, 58, 1962–1969. https://doi.org/10.1002/mnfr.201400245.

Article  CAS  Google Scholar 

Dorn, C., Bataille, F., Gaebele, E., Heilmann, J., & Hellerbrand, C. (2010). Xanthohumol feeding does not impair organ function and homoeostasis in mice. Food Chemistry Toxicology, 48, 1890–1897. https://doi.org/10.1016/j.fct.2010.04.030.

Article  CAS  Google Scholar 

Hussong, R., Frank, N., & Knauft, J. et al.(2005). A safety study of oral xanthohumol administration and its influence on fertility in Sprague Dawley rats. Molecular Nutrition & Food Research, 49, 861–867. https://doi.org/10.1002/mnfr.200500089.

Article  CAS  Google Scholar 

Langley, B. O., Joan, J. R., & Douglas, H., et al. (2021). Xanthohumol microbiome and signature in healthy adults (the XMaS Trial): Safety and tolerability results of a phase I triple-masked, placebo-controlled clinical trial. Molecular Nutrition & Food Research, 65, e2001170–e2001170. https://doi.org/10.1002/MNFR.202001170.

Article  Google Scholar 

Han, J. Y., Xia, T. S., & Jiang, Y. P., et al. (2024). Regulation of xanthohumol on serum uric acid level and bone metabolism in hyperuricemia rats. Academic Journal of Naval Medical University, 45, 260–267. https://doi.org/10.16781/j.CN31-2187/R.20230636.

Article  CAS  Google Scholar 

Bai, H. H., Xia, T. S., & Jiang, Y. P., et al. (2022). Absorption, metabolism, and pharmacokinetic profile of xanthohumol in rats as determined via UPLC-MS/MS. Biopharm Drug Dispos, 43, 11–22. https://doi.org/10.1002/bdd.2306.

Article  CAS  PubMed  Google Scholar 

Sun, X. L., Zhang, J. B., & Guo, Y. X. et al.(2021). Xanthohumol ameliorates memory impairment and reduces the deposition of β-amyloid in APP/PS1 mice via regulating the mTOR/LC3II and Bax/Bcl-2 signalling pathways. Journal of Pharmacy and Pharmacology, 73, 1230–1239. https://doi.org/10.1093/jpp/rgab052.

Article  PubMed  Google Scholar 

Sun, X., Xia, T. & Zhang, S. et al.(2022). Hops extract and xanthohumol ameliorate bone loss induced by iron overload via activating Akt/GSK3β/Nrf2 pathway. The Journal of Bone and Mineral Metabolism, 40, 375–388. https://doi.org/10.1007/s00774-021-01295-2.

Article  CAS  PubMed  Google Scholar 

Xia, T., Liu, X., & Wang, N. et al.(2022). PI3K/AKT/Nrf2 signalling pathway is involved in the ameliorative effects of xanthohumol on amyloid β-induced oxidative damage and bone loss. Journal of Pharmacy and Pharmacology, 74, 1017–1026. https://doi.org/10.1093/jpp/rgac007.

Article  PubMed  Google Scholar 

Xia, T. S., Lin, L. Y., & Zhang, Q. Y. et al.(2021). Humulus lupulus L. extract prevents ovariectomy-induced osteoporosis in mice and regulates activities of osteoblasts and osteoclasts. Chinese Journal of Integrative Medicine, 27, 31–38. https://doi.org/10.1007/s11655-019-2700-z.

Article  CAS  PubMed  Google Scholar 

Yan, F., Zhang, H., & Yuan, X. et al.(2023). Comparison of the different monosodium urate crystals in the preparation process and pro-inflammation. Advances in Rheumatology, 63, 39. https://doi.org/10.1186/s42358-023-00307-1.

Article  PubMed  Google Scholar 

Lin, Y. Y., Jean, Y. H., & Lin, S. C. et al.(2020). Etoricoxib prevents progression of osteolysis in repeated intra-articular monosodium urate-induced gouty arthritis in rats. Journal of Advanced Research, 24, 109–120. https://doi.org/10.1016/j.jare.2020.02.014.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sunk, I. G., Amoyo-Minar, L., & Niederreiter, B. et al.(2022). Dorso-ventral osteophytes of interphalangeal joints correlate with cartilage damage and synovial inflammation in hand osteoarthritis: a histological/radiographical study. Arthritis Research & Therapy, 24, 226. https://doi.org/10.1186/s13075-022-02911-w.

留言 (0)

沒有登入
gif