Astragaloside IV Reduces Lung Epithelial Cell Pyroptosis via TXNIP-NLRP3-GSDMD pathway

Celli, B. R., & Wedzicha, J. A. (2019). Update on clinical aspects of chronic obstructive pulmonary disease. The New England Journal of Medicine, 381(13), 1257–1266.

Article  CAS  PubMed  Google Scholar 

Christenson, S. A., et al. (2022). Chronic obstructive pulmonary disease. Lancet, 399(10342), 2227–2242.

Article  PubMed  Google Scholar 

Wang, L., et al. (2021). TREM-1 aggravates chronic obstructive pulmonary disease development via activation NLRP3 inflammasome-mediated pyroptosis. Inflammation Research, 70(9), 971–980.

Article  CAS  PubMed  Google Scholar 

Barnes, P. J. (2020). Oxidative stress-based therapeutics in COPD. Redox Biology, 33, 101544.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang, M. Y., et al. (2021). Cigarette smoke extract induces pyroptosis in human bronchial epithelial cells through the ROS/NLRP3/caspase-1 pathway. Life Sciences, 269, 119090.

Article  CAS  PubMed  Google Scholar 

Liu, X., et al. (2016). Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores. Nature, 535(7610), 153–158.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li, J. S., et al. (2020). Effective-constituent compatibility-based analysis of Bufei Yishen formula, a traditional herbal compound as an effective treatment for chronic obstructive pulmonary disease. Journal of Integrative Medicine, 18(4), 351–362.

Article  PubMed  Google Scholar 

Li, J., et al. (2020). Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling. Journal of Ethnopharmacology, 257, 112796.

Article  CAS  PubMed  Google Scholar 

Meng, P., et al. (2021). Molecular mechanism of astragaloside IV in improving endothelial dysfunction of cardiovascular diseases mediated by oxidative stress. Oxidative Medicine and Cellular Longevity, 2021, 1481236.

Article  PubMed  PubMed Central  Google Scholar 

Huang, D., et al. (2022). Astragaloside IV alleviates PM2.5-caused lung toxicity by inhibiting inflammasome-mediated pyroptosis via NLRP3/caspase-1 axis inhibition in mice. Biomedicine & Pharmacotherapy, 150, 112978.

Article  CAS  Google Scholar 

Wu, K., et al. (2020). Cigarette smoke extract increases mitochondrial membrane permeability through activation of adenine nucleotide translocator (ANT) in lung epithelial cells. Biochemical and Biophysical Research Communications, 525(3), 733–739.

Article  CAS  PubMed  Google Scholar 

Taniguchi, A., et al. (2021). Reactive oxygen species and antioxidative defense in chronic obstructive pulmonary disease. Antioxidants, 10(10), 1537.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Que, X., et al. (2024). Fantastic voyage: The journey of NLRP3 inflammasome activation. Genes & Diseases, 11(2), 819–829.

Article  CAS  Google Scholar 

Sun, J., & Li, Y. (2022). Pyroptosis and respiratory diseases: A review of current knowledge. Frontiers in Immunology, 13, 920464.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen, X., et al. (2023). Pregnancy-induced changes to the gut microbiota drive macrophage pyroptosis and exacerbate septic inflammation. Immunity, 56(2), 336–352. e9.

Article  CAS  PubMed  Google Scholar 

Wei, X., et al. (2022). Role of pyroptosis in inflammation and cancer. Cellular & Molecular Immunology, 19(9), 971–992.

Article  CAS  Google Scholar 

Barnes, P. J. (2016). Inflammatory mechanisms in patients with chronic obstructive pulmonary disease. The Journal of Allergy and Clinical Immunology, 138(1), 16–27.

Article  CAS  PubMed  Google Scholar 

Fang, Z. F., et al. (2023). Citrus peel extract protects against diesel exhaust particle-induced chronic obstructive pulmonary disease-like lung lesions and oxidative stress. Food & Function, 14(21), 9841–9856.

Article  CAS  Google Scholar 

Shen, Q., et al. (2023). Astragaloside IV attenuates podocyte apoptosis through ameliorating mitochondrial dysfunction by up-regulated Nrf2-ARE/TFAM signaling in diabetic kidney disease. Free Radical Biology and Medicine, 203, 45–57.

Article  CAS  PubMed  Google Scholar 

Xia, M. L., et al. (2020). Astragaloside IV inhibits astrocyte senescence: implication in Parkinson’s disease. Journal Neuroinflammation, 17(1), 105.

Article  CAS  Google Scholar 

Wang, X., et al. (2022). Astragaloside IV regulates the ferroptosis signaling pathway via the Nrf2/SLC7A11/GPX4 axis to inhibit PM2.5-mediated lung injury in mice. International Immunopharmacology, 112, 109186.

Article  CAS  PubMed  Google Scholar 

留言 (0)

沒有登入
gif