Understanding the Genetic Basis of Celiac Disease: A Comprehensive Review

Parzanese, I., Qehajaj, D., Patrinicola, F., Aralica, M., Chiriva-Internati, M., Stifter, S., & Grizzi, F. (2017). Celiac disease: From pathophysiology to treatment. World Journal of Gastrointestinal Pathophysiology, 8, 27. https://doi.org/10.4291/wjgp.v8.i2.27

Article  PubMed  PubMed Central  Google Scholar 

Garrote, J. A., Arranz, E., Gómez-González, E., León, A. J., Farré, C., Calvo, & Blanco-Quirós, A. (2005). IL6, IL10 and TGFB1 gene polymorphisms in coeliac disease: differences between DQ2 positive and negative patients. Allergologia et Immunopathologia, 33, 245–249. https://doi.org/10.1157/13080926

Article  CAS  Google Scholar 

Caio, G., Volta, U., Sapone, A., Leffler, D. A., De Giorgio, R., Catassi, C., & Fasano, A. (2019). Celiac disease: a comprehensive current review. BMC Medicine, 17, 1–20. https://doi.org/10.1186/s12916-019-1380-z

Article  CAS  Google Scholar 

Kaur, N., Singh, J., Minz, R. W., Anand, S., Saikia, B., Bhadada, S. K., & Dhanda, S. K. (2024). Shared and distinct genetics of pure type 1 diabetes and type 1 diabetes with celiac disease, homology in their auto-antigens and immune dysregulation states: a study from North India. ActaDiabetologica, 61(6), 791–805. https://doi.org/10.1097/2FAIA.0b013e318034194e

Article  CAS  Google Scholar 

Zhernakova A., Stahl E. A., Trynka G., Raychaudhuri S., Festen E. A., Franke L. et al. (2011) Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci. PLoS Genetics 7(2) https://doi.org/10.1371/journal.pgen.1002004

Trynka, G., Hunt, K. A., Bockett, N. A., Romanos, J., Mistry, V., & Szperl, A., et al. (2011). Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. Nature Genetics, 43(12), 1193–1201. https://doi.org/10.1038/ng.998.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ghazanfar, H., Javed, N., Lee, S., Shaban, M., Cordero, D., Acherjee, T., Hasan, K. Z., Jyala, A., Kandhi, S., Hussain, A. N., & Patel, H. (2023). Novel Therapies for Celiac Disease: A Clinical Review Article. Cureus, 15, e39004. https://doi.org/10.7759/cureus.39004.

Article  PubMed  PubMed Central  Google Scholar 

Zhang, J. M., & An, J. (2007). Cytokines, inflammation and pain. IntAnesthesiolClin, 45, 27. https://doi.org/10.1097/2FAIA.0b013e318034194e.

Article  CAS  Google Scholar 

Mc Manus, R., Wilson, A. G., Mansfield, J., Weir, D. G., Duff, G. W., & Kelleher, D. (1996). TNF2 a polymorphism of the tumour necrosis‐α gene promoter, is a component of the celiac disease major histocompatibility complex haplotype. European Journal of Immunology, 26, 2113–2118

Article  Google Scholar 

Kekik, Ç., Oguz, F. S., Karahan, G. E., Seyhun, Y., Aslan, E., Bayramicli, O., & Carin, M. (2011). IL-10 and TNF-alpha Gene Polymorphisms in Patients with Celiac Disease ÇölyakHastalarında IL-10 ve TNF-alfa Gen Polimorfizmleri. Turkish Journal of Immunology, 16, 1

Google Scholar 

Cataldo, F., Lio, D., Marino, V., Scola, L., Crivello, A., Mule, A. M., & del Tenue, C. (2003). Cytokine genotyping (TNF and IL-10) in patients with celiac disease and selective IgA deficiency. The American Journal of Gastroenterology, 98, 850–856. https://doi.org/10.1097/01.gim.0000204464.87540.39

Article  CAS  PubMed  Google Scholar 

Hahn-Zoric, M., Hytönen, A. M., Hanson, L. Å., Nilsson, L. Å., & Padyukov, L. (2003). Association of− 1087 IL10 and− 308 TNFA gene polymorphisms with serological markers of coeliac disease. Journal of Clinical Immunology, 23, 291–296. https://doi.org/10.1023/a:1024588800754

Article  CAS  PubMed  Google Scholar 

Hermann, C., Krikovszky, D., Vásárhelyi, B., Dezsőfi, A., & Madácsy, L. (2007). Polymorphisms of the TNF‐α gene and risk of celiac disease in T1DM children. Pediatric Diabetes, 8(3), 138–141. https://doi.org/10.1111/j.1399-5448.2007.00238.x

Article  PubMed  Google Scholar 

de Albuquerque Maranhão, R. M., Martins Esteves, F. A., Crovella, S., Segat, L., & Eleutério Souza, P. R. (2015). Tumor necrosis factor-α and interleukin-6 gene polymorphism association with susceptibility to celiac disease in Italian patients. Genetics and Molecular Research, 14, 16343–16352. https://doi.org/10.4238/2015

Article  PubMed  Google Scholar 

Sumnik, Z., Cinek, O., Bratanic, N., Kordonouri, O., Kulich, M., Roszai, B., & Schober, E. (2006). Risk of celiac disease in children with type 1 diabetes is modified by positivity for HLA-DQB1* 02-DQA1* 05 andTNF− 308A. Diabetes Care, 29, 858–863. https://doi.org/10.2337/diacare.29.04.06.dc05-1923

Article  CAS  PubMed  Google Scholar 

Romanos, J., Barisani, D., Trynka, G., Zhernakova, A., Bardella, M. T., & Wijmenga, C. (2009). Six new coeliac disease loci replicated in an Italian population confirm association with coeliac disease. Journal of Medical Genetics, 46, 60–63. https://doi.org/10.1136/jmg.2008.061457

Article  CAS  PubMed  Google Scholar 

Woolley, N., Mustalahti, K., Mäki, M., & Partanen, J. (2005). Cytokine gene polymorphisms and genetic association with coeliac disease in the Finnish population. Scandinavian Journal of Immunology, 61, 51–56. https://doi.org/10.1111/j.0300-9475.2005.01525.x

Article  CAS  PubMed  Google Scholar 

Barisani, D., Ceroni, S., Meneveri, R., Cesana, B. M., & Bardella, M. T. (2006). IL-10 polymorphisms are associated with early-onset celiac disease and severe mucosal damage in patients of Caucasian origin. Genetics in Medicine, 8, 169–174. https://doi.org/10.1097/01.gim.0000204464.87540.39

Article  CAS  PubMed  Google Scholar 

Akbulut, U. E., Çebi, A. H., Sağ, E., İkbal, M., & Çakır, M. (2017). Interleukin-6 and interleukin-17 gene polymorphism association with celiac disease in children. Turkish Journal of Gastroenterology, 28, 471–5. https://doi.org/10.5152/tjg.2017.17092

Article  Google Scholar 

Koskinen, L. L., Einarsdottir, E., Dukes, E., Heap, G. A., Dubois, P., Korponay-Szabo, I. R., & Saavalainen, P. (2009). Association study of the IL18RAP locus in three European populations with coeliac disease. Human Molecular Genetics, 18, 1148–1155. https://doi.org/10.1093/hmg/ddn438

Article  CAS  PubMed  Google Scholar 

Kara, Eren, M., Arslan, S., & Çilingir, O. (2021). IL-15 gene polymorphism in celiac disease patients and their siblings. Turkish Journal of Gastroenterology, 32, 349. https://doi.org/10.5152/tjg.2021.19083

Article  Google Scholar 

Dezsofi, A., Szebeni, B., Hermann, C. S., Kapitany, A., Veres, G., Sipka, S., & Arató, A. (2008). Frequencies of genetic polymorphisms of TLR4 and CD14 and of HLA-DQ genotypes in children with celiac disease, type 1 diabetes mellitus, or both. Journal of Pediatric Gastroenterology and Nutrition, 47, 283–287. https://doi.org/10.1097/mpg.0b013e31816de885

Article  CAS  PubMed  Google Scholar 

Popat, S., Hearle, N., Hogberg, L., Braegger, C. P., O’donoghue, D., Falth-Magnusson, K., & Houlston, R. S. (2002). Variation in the CTLA4/CD28 gene region confers an increased risk of coeliac disease. Annals of Human Genetics, 66, 125–137. https://doi.org/10.1017/s0003480002001021

Article  CAS  PubMed  Google Scholar 

Sansom, D. M. (2000). CD28, CTLA-4 and their ligands: who does what and to whom? Immunity, 101, 169 https://doi.org/10.1046/2Fj.1365-2567.2000.00121

Article  CAS  Google Scholar 

Woolley, N., Holopainen, P., Bourgain, C., Mustalahti, K., Collin, P., Mäki, M., & Partanen, J. (2002). CD80 (B7‐1) and CD86 (B7‐2) genes and genetic susceptibility to coeliac disease. European Journal of Immunogenetics, 29, 331–333. https://doi.org/10.1046/j.1365-2370.2002.00302.x

Article  CAS  PubMed  Google Scholar 

Nunez, C., Rueda, B., Martinez, A., Maluenda, C., Polanco, I., Lopez-Nevot, M. A., & Martin, J. (2006). A functional variant in the CD209 promoter is associated with DQ2-negative celiac disease in the Spanish population. World of Journal Gastroenterology: WJG, 12, 4397. https://doi.org/10.3748/wjg.v12.i27.4397

Article  CAS  PubMed Central  Google Scholar 

Mora, B., Bonamico, M., Indovina, P., Megiorni, F., Ferri, M., Carbone, M. C., & Mazzilli, M. C. (2003). CTLA-4+ 49 A/G dimorphism in Italian patients with celiac disease. Human Immunology, 64, 297–301

Article  CAS  PubMed  Google Scholar 

Zamani, M., Karami, F., Shirvani, F., Kia-Lashaki, L., & Shahbazkhani, B. (2014). The Role of CD14 and CTLA4 Gene Polymorphisms in Risk of Celiac Disease among Patients of Iranian Ethnicity. Cell Journal (Yakhteh), 16, 171

CAS  Google Scholar 

Clot, F., Fulchignoni‐Lataud, M. C., Renoux, C., Percopo, S., Bouguerra, F., Babron, M. C., & Serre, J. L. (1999). Linkage and association study of the CTLA‐4 region in coeliac disease for Italian and Tunisian populations. Tissue Antigens, 54, 527–530

Article  CAS  PubMed  Google Scholar 

Abel, M., Cellier, C., Kumar, N., Cerf-Bensussan, N., Schmitz, J., & Caillat-Zucman

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