A new direction in periodontitis treatment: biomaterial-mediated macrophage immunotherapy

Du M, Bo T, Kapellas K, Peres MA. Prediction models for the incidence and progression of periodontitis: a systematic review. J Clin Periodontol. 2018;45(12):1408–20.

Article  PubMed  Google Scholar 

Tang Y, Huang Q-X, Zheng D-W, Chen Y, Ma L, Huang C, Zhang X-Z. Engineered Bdellovibrio bacteriovorus: a countermeasure for biofilm-induced periodontitis. Mater Today. 2022;53:71–83.

Article  CAS  Google Scholar 

Okabe Y, Medzhitov R. Tissue biology perspective on macrophages. Nat Immunol. 2016;17(1):9–17.

Article  CAS  PubMed  Google Scholar 

Qiao W, Xie H, Fang J, Shen J, Li W, Shen D, Wu J, Wu S, Liu X, Zheng Y, Cheung KMC, Yeung KWK. Sequential activation of heterogeneous macrophage phenotypes is essential for biomaterials-induced bone regeneration. Biomaterials. 2021;276:121038.

Article  CAS  PubMed  Google Scholar 

Franklin RA. Fibroblasts and macrophages: collaborators in tissue homeostasis. Immunol Rev. 2021;302(1):86–103.

Article  CAS  PubMed  Google Scholar 

Almubarak A, Tanagala KKK, Papapanou PN, Lalla E, Momen-Heravi F. Disruption of monocyte and macrophage homeostasis in periodontitis. Front Immunol. 2020. https://doi.org/10.3389/fimmu.2020.00330.

Article  PubMed  PubMed Central  Google Scholar 

Zhang W, Guan N, Zhang X, Liu Y, Gao X, Wang L. Study on the imbalance of M1/M2 macrophage polarization in severe chronic periodontitis. Technol Health Care. 2023;31:117–24.

Article  PubMed  Google Scholar 

Zhu L-F, Li L, Wang X-Q, Pan L, Mei Y-M, Fu Y-W, Xu Y. M1 macrophages regulate TLR4/AP1 via paracrine to promote alveolar bone destruction in periodontitis. Oral Dis. 2019;25(8):1972–82.

Article  PubMed  Google Scholar 

Chen X, Wan Z, Yang L, Song S, Fu Z, Tang K, Chen L, Song Y. Exosomes derived from reparative M2-like macrophages prevent bone loss in murine periodontitis models via IL-10 mRNA. J Nanobiotechnol. 2022;20(1):110.

Article  CAS  Google Scholar 

Zhuang Z, Yoshizawa-Smith S, Glowacki A, Maltos K, Pacheco C, Shehabeldin M, Mulkeen M, Myers N, Chong R, Verdelis K, Garlet GP, Little S, Sfeir C. Induction of M2 macrophages prevents bone loss in murine periodontitis models. J Dent Res. 2018;98(2):200–8.

Article  PubMed  PubMed Central  Google Scholar 

Miao Y, He L, Qi X, Lin X. Injecting immunosuppressive M2 macrophages alleviates the symptoms of periodontitis in mice. Front Mol Biosci. 2020. https://doi.org/10.3389/fmolb.2020.603817.

Article  PubMed  PubMed Central  Google Scholar 

Li J, Li X, Pei M, Liu P. Acid-labile anhydride-linked doxorubicin-doxorubicin dimer nanoparticles as drug self-delivery system with minimized premature drug leakage and enhanced anti-tumor efficacy. Colloids Surf, B. 2020;192:111064.

Article  CAS  Google Scholar 

De Lauretis A, Øvrebø Ø, Romandini M, Lyngstadaas SP, Rossi F, Haugen HJ. From basic science to clinical practice: a review of current periodontal/mucogingival regenerative biomaterials. Adv Sci. 2024. https://doi.org/10.1002/advs.202308848.

Article  Google Scholar 

Murray PJ. Macrophage polarization. Annu Rev Physiol. 2017;79(1):541–66.

Article  CAS  PubMed  Google Scholar 

Slots J. Periodontitis: facts, fallacies and the future. Periodontology. 2017;75(1):7–23.

Article  Google Scholar 

Page RC, Schroeder HE. Pathogenesis of inflammatory periodontal disease. A summary of current work. Lab Invest. 1976;34(3):235–49.

CAS  PubMed  Google Scholar 

Hajishengallis G, Chavakis T, Hajishengallis E, Lambris JD. Neutrophil homeostasis and inflammation: novel paradigms from studying periodontitis. J Leukocyte Biol. 2014;98(4):539–48.

Article  PubMed  PubMed Central  Google Scholar 

Hajishengallis G, Moutsopoulos NM, Hajishengallis E, Chavakis T. Immune and regulatory functions of neutrophils in inflammatory bone loss. Semin Immunol. 2016;28(2):146–58.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang Z, Zhao Q, Jiang X, Li Z. The mechanism of efferocytosis in the pathogenesis of periodontitis and its possible therapeutic strategies. J Leukocyte Biol. 2023;113(4):365–75.

Article  PubMed  Google Scholar 

Hasan A, Palmer RM. A clinical guide to periodontology: pathology of periodontal disease. Br Dent J. 2014;216(8):457–61.

Article  CAS  PubMed  Google Scholar 

Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, Natoli G, Saeij JP, Schultze JL, Shirey KA, Sica A, Suttles J, Udalova I, van Ginderachter JA, Vogel SN, Wynn TA. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity. 2014;41(1):14–20.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mackaness GB. Cellular resistance to infection. J Exp Med. 1962;116(3):381–406.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nathan CF, Murray HW, Wiebe ME, Rubin BY. Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity. J Exp Med. 1983;158(3):670–89.

Article  CAS  PubMed  Google Scholar 

Stein M, Keshav S, Harris N, Gordon S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J Exp Med. 1992;176(1):287–92.

Article  CAS  PubMed  Google Scholar 

Mills CD, Kincaid K, Alt JM, Heilman MJ, Hill AM. M-1/M-2 macrophages and the Th1/Th2 paradigm. J Immunol. 2000;164(12):6166–73.

Article  CAS  PubMed  Google Scholar 

Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol. 2005;175(1):5–14.

CAS  PubMed  Google Scholar 

Martinez FO, Gordon S. The M1 and M2 paradigm of macrophage activation: time for reassessment. F1000Prime Rep. 2014;6:13.

Article  PubMed  PubMed Central  Google Scholar 

Shapouri-Moghaddam A, Mohammadian S, Vazini H, Taghadosi M, Esmaeili S-A, Mardani F, Seifi B, Mohammadi A, Afshari JT, Sahebkar A. Macrophage plasticity, polarization, and function in health and disease. J Cell Physiol. 2018;233(9):6425–40.

Article  CAS  PubMed  Google Scholar 

Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 2004;25(12):677–86.

Article  CAS  PubMed  Google Scholar 

Mosser DM, Edwards JP. Erratum: exploring the full spectrum of macrophage activation. Nat Rev Immunol. 2010;10(6):460–460.

Article  CAS  Google Scholar 

Keeler GD, Durdik JM, Stenken JA. Localized delivery of dexamethasone-21-phosphate via microdialysis implants in rat induces M(GC) macrophage polarization and alters CCL2 concentrations. Acta Biomater. 2015;12:11–20.

Article  CAS  PubMed  Google Scholar 

Yang J, Zhu Y, Duan D, Wang P, Xin Y, Bai L, Liu Y, Xu Y. Enhanced activity of macrophage M1/M2 phenotypes in periodontitis. Arch Oral Biol. 2018;96:234–42.

Article  CAS 

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