Aber ER, Griffey CJ, Davies T, Li AM, Yang YJ, Croce KR, Goldman JE, Grutzendler J, Canman JC, Yamamoto A (2022) Oligodendroglial macroautophagy is essential for myelin sheath turnover to prevent neurodegeneration and death. Cell Rep 41(3):111480. https://doi.org/10.1016/j.celrep.2022.111480
Article CAS PubMed PubMed Central Google Scholar
Absinta M, Maric D, Gharagozloo M, Garton T, Smith MD, Jin J, Fitzgerald KC, Song A, Liu P, Lin J-P, Wu T, Johnson KR, McGavern DB, Schafer DP, Calabresi PA, Reich DS (2021) A lymphocyte–microglia–astrocyte axis in chronic active multiple sclerosis. Nature 597(7878):709–714. https://doi.org/10.1038/s41586-021-03892-7
Article CAS PubMed PubMed Central Google Scholar
Alirezaei M, Fox HS, Flynn CT, Moore CS, Hebb ALO, Frausto RF, Bhan V, Kiosses WB, Whitton JL, Robertson GS, Crocker SJ (2009) Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis. Autophagy 5(2):152–158. https://doi.org/10.4161/auto.5.2.7348
Article CAS PubMed Google Scholar
Anders S, Pyl PT, Huber W (2015) HTSeq—a Python framework to work with high-throughput sequencing data. Bioinformatics 31(2):166–169. https://doi.org/10.1093/bioinformatics/btu638
Article CAS PubMed Google Scholar
Antony JM, Van Marle G, Opii W, Butterfield DA, Mallet F, Yong VW, Wallace JL, Deacon RM, Warren K, Power C (2004) Human endogenous retrovirus glycoprotein–mediated induction of redox reactants causes oligodendrocyte death and demyelination. Nat Neurosci 7(10):1088–1095. https://doi.org/10.1038/nn1319
Article CAS PubMed Google Scholar
Antony JM, Izad M, Bar-Or A, Warren KG, Vodjgani M, Mallet F, Power C (2006) Quantitative Analysis of Human Endogenous Retrovirus-W env in Neuroinflammatory Diseases. AIDS Res Hum Retroviruses 22(12):1253–1259. https://doi.org/10.1089/aid.2006.22.1253
Article CAS PubMed Google Scholar
Antony JM, Zhu Y, Izad M, Warren KG, Vodjgani M, Mallet F, Power C (2007) Comparative expression of human endogenous retrovirus-W genes in multiple sclerosis. AIDS Res Hum Retroviruses 23(10):1251–1256. https://doi.org/10.1089/aid.2006.0274
Article CAS PubMed Google Scholar
Bae H-G, Kim TK, Suk HY, Jung S, Jo D-G (2020) White matter and neurological disorders. Arch Pharm Res 43(9):920–931. https://doi.org/10.1007/s12272-020-01270-x
Article CAS PubMed Google Scholar
Belshaw R, Pereira V, Katzourakis A, Talbot G, Pačes J, Burt A, Tristem M (2004) Long-term reinfection of the human genome by endogenous retroviruses. Proc Natl Acad Sci 101(14):4894–4899. https://doi.org/10.1073/pnas.0307800101
Article CAS PubMed PubMed Central Google Scholar
Carlson M (2017) org.Hs.eg.dbb: Genome wide annotation for Human. R package version 3.8.2
Correale J, Farez MF (2015) The role of astrocytes in multiple sclerosis progression. Front Neurol. https://doi.org/10.3389/fneur.2015.00180
Article PubMed PubMed Central Google Scholar
Cudrici C, Niculescu T, Niculescu F, Shin ML, Rus H (2006) Oligodendrocyte cell death in pathogenesis of multiple sclerosis: Protection of oligodendrocytes from apoptosis by complement. J Rehabil Res Dev 43(1):123. https://doi.org/10.1682/JRRD.2004.08.0111
Cui Q-L, Kuhlmann T, Miron VE, Leong SY, Fang J, Gris P, Kennedy TE, Almazan G, Antel J (2013) Oligodendrocyte progenitor cell susceptibility to injury in multiple sclerosis. Am J Pathol 183(2):516–525. https://doi.org/10.1016/j.ajpath.2013.04.016
Article CAS PubMed Google Scholar
Dobin A, Davis CA, Schlesinger F, Drenkow J, Zaleski C, Jha S, Batut P, Chaisson M, Gingeras TR (2013) STAR: ultrafast universal RNA-seq aligner. Bioinformatics 29(1):15–21. https://doi.org/10.1093/bioinformatics/bts635
Article CAS PubMed Google Scholar
Elkjaer ML, Frisch T, Reynolds R, Kacprowski T, Burton M, Kruse TA, Thomassen M, Baumbach J, Illes Z (2019) Molecular signature of different lesion types in the brain white matter of patients with progressive multiple sclerosis. Acta Neuropathol Commun 7(1):205. https://doi.org/10.1186/s40478-019-0855-7
Article CAS PubMed PubMed Central Google Scholar
Elkjaer ML, Frisch T, Tonazzolli A, Röttger R, Reynolds R, Baumbach J, Illes Z (2021) Unbiased examination of genome-wide human endogenous retrovirus transcripts in MS brain lesions. Mult Scler J 27(12):1829–1837. https://doi.org/10.1177/1352458520987269
Frankenhaeuser B, Schneider D (1951) Some electrophysiological observations on isolated single myelinated nerve fibres (saltatory conduction). J Physiol 115(2):177–184. https://doi.org/10.1113/jphysiol.1951.sp004662
Article CAS PubMed PubMed Central Google Scholar
García-Montojo M, De La Hera B, Varadé J, De La Encarnación A, Camacho I, Domínguez-Mozo M, Arias-Leal A, García-Martínez Á, Casanova I, Izquierdo G, Lucas M, Fedetz M, Alcina A, Arroyo R, Matesanz F, Urcelay E, Alvarez-Lafuente R (2014) HERV-W polymorphism in chromosome X is associated with multiple sclerosis risk and with differential expression of MSRV. Retrovirology 11(1):2. https://doi.org/10.1186/1742-4690-11-2
Article PubMed PubMed Central Google Scholar
Ghasemi N, Razavi S, Nikzad E (2017) Multiple sclerosis: pathogenesis, symptoms, diagnoses and cell-based therapy. Cell J Yakhteh 19(1). https://doi.org/10.22074/cellj.2016.4867
Grandi N, Tramontano E (2018a) HERV envelope proteins: physiological role and pathogenic potential in cancer and autoimmunity. Front Microbiol 9:462. https://doi.org/10.3389/fmicb.2018.00462
Article PubMed PubMed Central Google Scholar
Grandi N, Tramontano E (2018b) Human endogenous retroviruses are ancient acquired elements still shaping innate immune responses. Front Immunol 9:2039. https://doi.org/10.3389/fimmu.2018.02039
Article CAS PubMed PubMed Central Google Scholar
Grandi N, Cadeddu M, Blomberg J, Tramontano E (2016) Contribution of type W human endogenous retroviruses to the human genome: characterization of HERV-W proviral insertions and processed pseudogenes. Retrovirology 13(1):67. https://doi.org/10.1186/s12977-016-0301-x
Article CAS PubMed PubMed Central Google Scholar
Kremer D, Gruchot J, Weyers V, Oldemeier L, Göttle P, Healy L, Ho J, Jang KT, Xu Y, Volsko C, Dutta R, Trapp BD, Perron H, Hartung H-P, Küry P (2019) pHERV-W envelope protein fuels microglial cell-dependent damage of myelinated axons in multiple sclerosis. Proc Natl Acad Sci 116(30):15216–15225. https://doi.org/10.1073/pnas.1901283116
Article CAS PubMed PubMed Central Google Scholar
Laufer G, Mayer J, Mueller BF, Mueller-Lantzsch N, Ruprecht K (2009) Analysis of transcribed human endogenous retrovirus W env loci clarifies the origin of multiple sclerosis-associated retrovirus envsequences. Retrovirology 6(1):37. https://doi.org/10.1186/1742-4690-6-37
Article CAS PubMed PubMed Central Google Scholar
Libbey JE, McCoy LL, Fujinami RS (2007) Molecular Mimicry in Multiple Sclerosis. International Review of Neurobiology. Elsevier, pp 127–147
Liu R, Du S, Zhao L, Jain S, Sahay K, Rizvanov A, Lezhnyova V, Khaibullin T, Martynova E, Khaiboullina S, Baranwal M (2022) Autoreactive lymphocytes in multiple sclerosis: Pathogenesis and treatment target. Front Immunol 13:996469. https://doi.org/10.3389/fimmu.2022.996469
Article CAS PubMed PubMed Central Google Scholar
Love MI, Huber W, Anders S (2014) Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol 15(12):550. https://doi.org/10.1186/s13059-014-0550-8
Article CAS PubMed PubMed Central Google Scholar
Luo C, Jian C, Liao Y, Huang Q, Wu Y, Liu X, Zou D, Wu Y (2017) The role of microglia in multiple sclerosis. Neuropsychiatr Dis Treat 13:1661–1667. https://doi.org/10.2147/NDT.S140634
Article CAS PubMed PubMed Central Google Scholar
Marrodan M, Gaitán MI, Correale J (2020) Spinal cord Involvement in MS and other demyelinating diseases. Biomedicines 8(5):130. https://doi.org/10.3390/biomedicines8050130
Article CAS PubMed PubMed Central Google Scholar
Miller SJ (2018) Astrocyte heterogeneity in the adult central nervous system. Front Cell Neurosci 12:401. https://doi.org/10.3389/fncel.2018.00401
Article CAS PubMed PubMed Central Google Scholar
Morris G, Maes M, Murdjeva M, Puri BK (2019) Do human endogenous retroviruses contribute to multiple sclerosis, and if so, How? Mol Neurobiol 56(4):2590–2605. https://doi.org/10.1007/s12035-018-1255-x
Article CAS PubMed Google Scholar
Nave K-A, Trapp BD (2008) Axon-glial signaling and the glial support of axon function. Annu Rev Neurosci 31(1):535–561. https://doi.org/10.1146/annurev.neuro.30.051606.094309
Article CAS PubMed Google Scholar
Newman AM, Steen CB, Liu CL, Gentles AJ, Chaudhuri AA, Scherer F, Khodadoust MS, Esfahani MS, Luca BA, Steiner D, Diehn M, Alizadeh AA (2019) Determining cell type abundance and expression from bulk tissues with digital cytometry. Nat Biotechnol 37(7):773–782. https://doi.org/10.1038/s41587-019-0114-2
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