Collaborators GMD (2022) Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990–2019: a systematic analysis for the global burden of disease study 2019. Lancet Psych 9:137–150. https://doi.org/10.1016/s2215-0366(21)00395-3
Malhi GS, Mann JJ (2018) Depression. Lancet 392:2299–2312. https://doi.org/10.1016/s0140-6736(18)31948-2
Hodes GE, Kana V, Menard C, Merad M, Russo SJ (2015) Neuroimmune mechanisms of depression. Nat Neurosci 18:1386–1393. https://doi.org/10.1038/nn.4113
Article CAS PubMed PubMed Central Google Scholar
Enache D, Pariante CM, Mondelli V (2019) Markers of central inflammation in major depressive disorder: a systematic review and meta-analysis of studies examining cerebrospinal fluid, positron emission tomography and post-mortem brain tissue. Brain Behav Immun 81:24–40. https://doi.org/10.1016/j.bbi.2019.06.015
Afridi R, Suk K (2021) Neuroinflammatory basis of depression: learning from experimental models. Front Cell Neurosci 15:691067. https://doi.org/10.3389/fncel.2021.691067
Article CAS PubMed PubMed Central Google Scholar
Wang AK, Miller BJ (2018) Meta-analysis of cerebrospinal fluid cytokine and tryptophan catabolite alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder, and depression. Schizophr Bull 44:75–83. https://doi.org/10.1093/schbul/sbx035
Levine J, Barak Y, Chengappa KN, Rapoport A, Rebey M, Barak V (1999) Cerebrospinal cytokine levels in patients with acute depression. Neuropsychobiology 40:171–176. https://doi.org/10.1159/000026615
Article CAS PubMed Google Scholar
Schaefer M, Capuron L, Friebe A, Diez-Quevedo C, Robaeys G, Neri S et al (2012) Hepatitis C infection, antiviral treatment and mental health: a European expert consensus statement. J Hepatol 57:1379–1390. https://doi.org/10.1016/j.jhep.2012.07.037
Yao R, Pan R, Shang C, Li X, Cheng J, Xu J et al (2020) Translocator protein 18 kDa (TSPO) deficiency inhibits microglial activation and impairs mitochondrial function. Front Pharmacol 11:986. https://doi.org/10.3389/fphar.2020.00986
Article CAS PubMed PubMed Central Google Scholar
Li H, Sagar AP, Kéri S (2018) Translocator protein (18kDa TSPO) binding, a marker of microglia, is reduced in major depression during cognitive-behavioral therapy. Prog Neuropsychopharmacol Biol Psychiatry 83:1–7. https://doi.org/10.1016/j.pnpbp.2017.12.011
Article CAS PubMed Google Scholar
Setiawan E, Wilson AA, Mizrahi R, Rusjan PM, Miler L, Rajkowska G et al (2015) Role of translocator protein density, a marker of neuroinflammation, in the brain during major depressive episodes. JAMA Psychiat 72:268–275. https://doi.org/10.1001/jamapsychiatry.2014.2427
Steiner J, Walter M, Gos T, Guillemin GJ, Bernstein HG, Sarnyai Z et al (2011) Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic neurotransmission? J Neuroinflam 8:94. https://doi.org/10.1186/1742-2094-8-94
Torres-Platas SG, Cruceanu C, Chen GG, Turecki G, Mechawar N (2014) Evidence for increased microglial priming and macrophage recruitment in the dorsal anterior cingulate white matter of depressed suicides. Brain Behav Immun 42:50–59. https://doi.org/10.1016/j.bbi.2014.05.007
Article CAS PubMed Google Scholar
Rahimian R, Wakid M, O’Leary LA, Mechawar N (2021) The emerging tale of microglia in psychiatric disorders. Neurosci Biobehav Rev 131:1–29. https://doi.org/10.1016/j.neubiorev.2021.09.023
Clark SM, Pocivavsek A, Nicholson JD, Notarangelo FM, Langenberg P, McMahon RP et al (2016) Reduced kynurenine pathway metabolism and cytokine expression in the prefrontal cortex of depressed individuals. J Psychiatry Neurosci 41:386–394. https://doi.org/10.1503/jpn.150226
Article PubMed PubMed Central Google Scholar
Dionisie V, Filip GA, Manea MC, Manea M, Riga S (2021) The anti-inflammatory role of SSRI and SNRI in the treatment of depression: a review of human and rodent research studies. Inflammopharmacology 29:75–90. https://doi.org/10.1007/s10787-020-00777-5
Article CAS PubMed Google Scholar
Lyu D, Wang F, Zhang M, Yang W, Huang H, Huang Q et al (2022) Ketamine induces rapid antidepressant effects via the autophagy-NLRP3 inflammasome pathway. Psychopharmacology 239:3201–3212. https://doi.org/10.1007/s00213-022-06201-w
Article CAS PubMed Google Scholar
Lu Y, Ding X, Wu X, Huang S (2020) Ketamine inhibits LPS-mediated BV2 microglial inflammation via NMDA receptor blockage. Fundam Clin Pharmacol 34:229–237. https://doi.org/10.1111/fcp.12508
Article CAS PubMed Google Scholar
Mariani N, Everson J, Pariante CM, Borsini A (2022) Modulation of microglial activation by antidepressants. J Psychopharmacol 36:131–150. https://doi.org/10.1177/02698811211069110
Article CAS PubMed PubMed Central Google Scholar
Henry CJ, Huang Y, Wynne A, Hanke M, Himler J, Bailey MT et al (2008) Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia. J Neuroinflammation 5:15. https://doi.org/10.1186/1742-2094-5-15
Article CAS PubMed PubMed Central Google Scholar
Nettis MA, Lombardo G, Hastings C, Zajkowska Z, Mariani N, Nikkheslat N et al (2021) Augmentation therapy with minocycline in treatment-resistant depression patients with low-grade peripheral inflammation: results from a double-blind randomised clinical trial. Neuropsychopharmacology 46:939–948. https://doi.org/10.1038/s41386-020-00948-6
Article CAS PubMed PubMed Central Google Scholar
Cao ZY, Liu YZ, Li JM, Ruan YM, Yan WJ, Zhong SY et al (2020) Glycyrrhizic acid as an adjunctive treatment for depression through anti-inflammation: a randomized placebo-controlled clinical trial. J Affect Disord 265:247–254. https://doi.org/10.1016/j.jad.2020.01.048
Article CAS PubMed Google Scholar
Kang HJ, Bae KY, Kim SW, Kim JT, Park MS, Cho KH et al (2016) Effects of interleukin-6, interleukin-18, and statin use, evaluated at acute stroke, on post-stroke depression during 1-year follow-up. Psychoneuroendocrinology 72:156–160. https://doi.org/10.1016/j.psyneuen.2016.07.001
Article CAS PubMed Google Scholar
Sun X, Zaydman MA, Cui J (2012) Regulation of voltage-activated K+ channel gating by transmembrane beta subunits. Front Pharmacol 3:63. https://doi.org/10.3389/fphar.2012.00063
Article CAS PubMed PubMed Central Google Scholar
Chen SR, Cai YQ, Pan HL (2009) Plasticity and emerging role of BKCa channels in nociceptive control in neuropathic pain. J Neurochem 110:352–362. https://doi.org/10.1111/j.1471-4159.2009.06138.x
Article CAS PubMed PubMed Central Google Scholar
Huang S, Chen T, Suo Q, Shi R, Khan H, Ma Y et al (2021) BK channel-mediated microglial phagocytosis alleviates neurological deficit after ischemic stroke. Front Cell Neurosci 15:683769. https://doi.org/10.3389/fncel.2021.683769
Article CAS PubMed PubMed Central Google Scholar
Sun X (2023) BK channels in microglia. Brain Sci Adv 9:15–23. https://doi.org/10.26599/BSA.2023.9050001
Schilling T, Eder C (2007) Ion channel expression in resting and activated microglia of hippocampal slices from juvenile mice. Brain Res 1186:21–28. https://doi.org/10.1016/j.brainres.2007.10.027
Article CAS PubMed Google Scholar
Hayashi Y, Kawaji K, Sun L, Zhang X, Koyano K, Yokoyama T et al (2011) Microglial Ca2+-activated K+ channels are possible molecular targets for the analgesic effects of S-ketamine on neuropathic pain. J Neurosci 31:17370–17382. https://doi.org/10.1523/jneurosci.4152-11.2011
Article CAS PubMed PubMed Central Google Scholar
Hayashi Y, Morinaga S, Zhang J, Satoh Y, Meredith AL, Nakata T et al (2016) BK channels in microglia are required for morphine-induced hyperalgesia. Nat Commun 7:11697. https://doi.org/10.1038/ncomms11697
Article CAS PubMed PubMed Central Google Scholar
Ma J, Wang J, Deng K, Gao Y, Xiao W, Hou J et al (2022) The effect of MaxiK channel on regulating the activation of NLRP3 inflammasome in rats of blast-induced traumatic brain injury. Neuroscience 482:132–142. https://doi.org/10.1016/j.neuroscience.2021.12.019
Article CAS PubMed Google Scholar
Yang X, Wang G, Cao T, Zhang L, Ma Y, Jiang S et al (2019) Large-conductance calcium-activated potassium channels mediate lipopolysaccharide-induced activation of murine microglia. J Biol Chem 294:12921–12932. https://doi.org/10.1074/jbc.RA118.006425
Article CAS PubMed PubMed Central Google Scholar
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