Wang L, Yu C, Chang T, Zhang M, Song S, Xiong C, et al. In situ repair abilities of human umbilical cord-derived mesenchymal stem cells and autocrosslinked hyaluronic acid gel complex in rhesus monkeys with intrauterine adhesion. Sci Adv. 2020;6:eaba6357.
Article CAS PubMed PubMed Central Google Scholar
Ma J, Zhan H, Li W, Zhang L, Yun F, Wu R, et al. Recent trends in therapeutic strategies for repairing endometrial tissue in intrauterine adhesion. Biomater Res. 2021;25:40.
Article PubMed PubMed Central Google Scholar
Paukszto L, Mikolajczyk A, Jastrzebski JP, Majewska M, Dobrzyn K, Kiezun M, et al. Transcriptome, spliceosome and editome expression patterns of the porcine endometrium in response to a single subclinical dose of enteritidis lipopolysaccharide. Int J Mol Sci. 2020;21:4217.
Article CAS PubMed PubMed Central Google Scholar
Wei C, Pan Y, Zhang Y, Dai Y, Jiang L, Shi L, et al. Overactivated sonic hedgehog signaling aggravates intrauterine adhesion via inhibiting autophagy in endometrial stromal cells. Cell Death Dis. 2020;11:755.
Article CAS PubMed PubMed Central Google Scholar
Peng Y, Peng C, Fang Z, Chen G. Bioinformatics analysis identifies molecular markers regulating development and progression of endometriosis and potential therapeutic drugs. Front Genet. 2021;12:622683.
Article CAS PubMed PubMed Central Google Scholar
Li B, Zhang Q, Sun J, Lai D. Human amniotic epithelial cells improve fertility in an intrauterine adhesion mouse model. Stem Cell Res Ther. 2019;10:257.
Article PubMed PubMed Central Google Scholar
Ouyang X, You S, Zhang Y, Zhang C, Zhang G, Shao X, et al. Transplantation of human amnion epithelial cells improves endometrial regeneration in Rat Model of Intrauterine adhesions. Stem Cells Dev. 2020;29:1346–62.
Article CAS PubMed Google Scholar
Lee W-L, Liu C-H, Cheng M, Chang W-H, Liu W-M, Wang P-H. Focus on the primary prevention of intrauterine adhesions: current concept and vision. Int J Mol Sci. 2021;22:5175.
Article PubMed PubMed Central Google Scholar
Foix A, Bruno RO, Davison T, Lema B. The pathology of postcurettage intrauterine adhesions. Am J Obstet Gynecol. 1966;96:1027–33.
Article CAS PubMed Google Scholar
Bernard M, Dieudé M, Yang B, Hamelin K, Underwood K, Hébert M-J. Autophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF. Autophagy. 2014;10:2193–207.
Article CAS PubMed Google Scholar
Kramann R, Schneider RK. The identification of fibrosis-driving myofibroblast precursors reveals new therapeutic avenues in myelofibrosis. Blood. 2018;131:2111–19.
Article CAS PubMed Google Scholar
Hinz B. Formation and function of the myofibroblast during tissue repair. J Invest Dermatol. 2007;127:526–37.
Article CAS PubMed Google Scholar
Zhou Z, Jiang R, Yang X, Guo H, Fang S, Zhang Y, et al. circRNA mediates silica-Induced Macrophage Activation Via HECTD1/ZC3H12A-Dependent ubiquitination. Theranostics. 2018;8:575–92.
Article CAS PubMed PubMed Central Google Scholar
Rikard SM, Athey TL, Nelson AR, Christiansen SLM, Lee J-J, Holmes JW, et al. Multiscale coupling of an agent-based model of tissue fibrosis and a logic-based model of intracellular signaling. Front Physiol. 2019;10:1481.
Article PubMed PubMed Central Google Scholar
Singh S, Torzewski M. Fibroblasts and their pathological functions in the fibrosis of aortic valve sclerosis and atherosclerosis. Biomolecules. 2019;9:472.
Article CAS PubMed PubMed Central Google Scholar
Zhao X, Zhao Q, Zhu X, Huang H, Wan X, Guo R, et al. Study on the correlation among dysbacteriosis, imbalance of cytokine and the formation of intrauterine adhesion. Ann Transl Med. 2020;8:52.
Article CAS PubMed PubMed Central Google Scholar
Xue X, Chen Q, Zhao G, Zhao J-Y, Duan Z, Zheng P-S. The overexpression of TGF-β and CCN2 in Intrauterine adhesions involves the NF-κB signaling pathway. PLoS ONE. 2015;10:e0146159.
Article PubMed PubMed Central Google Scholar
Zhou Q, Wu X, Hu J, Yuan R. Abnormal expression of fibrosis markers, estrogen receptor α and stromal derived factor–1/chemokine (C–X–C motif) receptor–4 axis in intrauterine adhesions. Int J Mol Med. 2018;42:81–90.
PubMed PubMed Central Google Scholar
Zhu H, Pan Y, Jiang Y, Li J, Zhang Y, Zhang S. Activation of the Hippo/TAZ pathway is required for menstrual stem cells to suppress myofibroblast and inhibit transforming growth factor β signaling in human endometrial stromal cells. Hum Reprod. 2019;34:635–45.
Article CAS PubMed Google Scholar
Chen G, Liu L, Sun J, Zeng L, Cai H, He Y. Foxf2 and Smad6 co-regulation of collagen 5A2 transcription is involved in the pathogenesis of intrauterine adhesion. J Cell Mol Med. 2020;24:2802–18.
Article CAS PubMed PubMed Central Google Scholar
Bueno M, Calyeca J, Rojas M, Mora AL. Mitochondria dysfunction and metabolic reprogramming as drivers of idiopathic pulmonary fibrosis. Redox Biol. 2020;33:101509.
Article CAS PubMed PubMed Central Google Scholar
Zhao X, Kwan JYY, Yip K, Liu PP, Liu F-F. Targeting metabolic dysregulation for fibrosis therapy. Nat Rev Drug Discov. 2020;19:57–75.
Article CAS PubMed Google Scholar
Du K, Hyun J, Premont RT, Choi SS, Michelotti GA, Swiderska-Syn M, et al. Hedgehog-YAP signaling pathway regulates glutaminolysis to control activation of hepatic stellate cells. Gastroenterology. 2018;154:1465–79.
Article CAS PubMed Google Scholar
Bernard K, Logsdon NJ, Benavides GA, Sanders Y, Zhang J, Darley-Usmar VM, et al. Glutaminolysis is required for transforming growth factor-β1-induced myofibroblast differentiation and activation. J Biol Chem. 2018;293:1218–28.
Article CAS PubMed Google Scholar
Stegen S, Laperre K, Eelen G, Rinaldi G, Fraisl P, Torrekens S, et al. HIF-1α metabolically controls collagen synthesis and modification in chondrocytes. Nature. 2019;565:511–15.
Article CAS PubMed PubMed Central Google Scholar
Spinelli JB, Haigis MC. The multifaceted contributions of mitochondria to cellular metabolism. Nat Cell Biol. 2018;20:745–54.
Article CAS PubMed PubMed Central Google Scholar
Zhang C, Liu J, Zhao Y, Yue X, Zhu Y, Wang X, et al. Glutaminase 2 is a novel negative regulator of small GTPase Rac1 and mediates p53 function in suppressing metastasis. Elife. 2016;5:e10727.
Article PubMed PubMed Central Google Scholar
Zhang Q, Gao Y, Zhang J, Li Y, Chen J, Huang R, et al. L-Asparaginase exerts neuroprotective effects in an SH-SY5Y-A53T Model of Parkinson’s disease by regulating glutamine metabolism. Front Mol Neurosci. 2020;13:563054.
Article CAS PubMed PubMed Central Google Scholar
Altman BJ, Stine ZE, Dang CV. From Krebs to clinic: glutamine metabolism to cancer therapy. Nat Rev Cancer. 2016;16:619–34.
Article CAS PubMed PubMed Central Google Scholar
Li J, Zuo L, Tian Y, He Y, Zhang Z, Guo P, et al. Spontaneous colitis in IL-10-deficient mice was ameliorated via inhibiting glutaminase1. J Cell Mol Med. 2019;23:5632–41.
Article CAS PubMed PubMed Central Google Scholar
Morita M, Gravel S-P, Hulea L, Larsson O, Pollak M, St-Pierre J, et al. mTOR coordinates protein synthesis, mitochondrial activity and proliferation. Cell Cycle. 2015;14:473–80.
Article CAS PubMed PubMed Central Google Scholar
Spormann L, Rennert C, Kolbe E, Ott F, Lossius C, Lehmann R, et al. Cyclopamine and rapamycin synergistically inhibit mTOR signalling in mouse hepatocytes, revealing an interaction of hedgehog and mTor signalling in the liver. Cells. 2020;9:1817.
Article CAS PubMed PubMed Central Google Scholar
Zhang C, Chan CCY, Cheung KF, Chau MKM, Yap DYH, Ma MKM, et al. Effect of mycophenolate and rapamycin on renal fibrosis in lupus nephritis. Clin Sci (Lond). 2019;133:1721–44.
Article CAS PubMed Google Scholar
Woodcock HV, Eley JD, Guillotin D, Platé M, Nanthakumar CB, Martufi M, et al. The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis. Nat Commun. 2019;10:6.
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