Characterization of anthracycline-induced cardiotoxicity by diffusion tensor magnetic resonance imaging

Addison D, Neilan TG, Barac A, Scherrer-Crosbie M, Okwuosa TM, Plana JC, Reding KW, Taqueti VR, Yang EH, Zaha VG, American Heart Association Council on Cardiovascular Radiology and Intervention; Cardio-Oncology Committee of the Council on Clinical Cardiology and Council on Genomic and Precision Medicine; and Council on Cardiovascular and Stroke Nursing (2023) Cardiovascular imaging in contemporary cardio-oncology: a scientific statement from the american heart association. Circulation. https://doi.org/10.1161/CIR.0000000000001174

Article  Google Scholar 

Antoniak S, Phungphong S, Cheng Z, Jensen BC (2022) Novel mechanisms of anthracycline-induced cardiovascular toxicity: a focus on thrombosis, cardiac atrophy, and programmed cell death. Front Cardiovasc Med 8:817977. https://doi.org/10.3389/fcvm.2021.817977

Article  CAS  PubMed  PubMed Central  Google Scholar 

Arbelo E, Protonotarios A, Gimeno JR, Arbustini E, Barriales-Villa R, Basso C, Bezzina CR, Biagini E, Blom NA, De Boer RA, De Winter T, Elliott PM, Flather M, Garcia-Pavia P, Haugaa KH, Ingles J, Jurcut RO, Klaassen S, Limongelli G, Loeys B, Mogensen J, Olivotto I, Pantazis A, Sharma S, Van Tintelen JP, Ware JS, Kaski JP, ESC Scientific Document Group, Charron P, Imazio M, Abdelhamid M, Aboyans V, Arad M, Asselbergs FW, Asteggiano R, Bilinska Z, Bonnet D, Bundgaard H, Cardim NM, Čelutkienė J, Cikes M, De Ferrari GM, Dusi V, Falk V, Fauchier L, Gandjbakhch E, Heliö T, Koskinas K, Kotecha D, Landmesser U, Lazaros G, Lewis BS, Linhart A, Løchen M-L, Meder B, Mindham R, Moon J, Nielsen JC, Petersen S, Prescott E, Sheppard MN, Sinagra G, Sitges M, Tfelt-Hansen J, Touyz R, Veltrop R, Veselka J, Wahbi K, Wilde A, Zeppenfeld K, Kichou B, Sisakian H, Scherr D, Gerber B, Džubur A, Gospodinova M, Planinc I, Moustra HH, Zemánek D, Jensen MSK, Samir A, Palm K, Heliö T, Wahbi K, Schulze-Bahr E, Haralambos V, Sepp R, Aðalsteinsdóttir B, Ward D, Blich M, Sinagra G, Poniku A, Lunegova O, Rudzitis A, Kassab R, Barysienė J, Huijnen S, Felice T, Vataman E, Pavlovic N, Doghmi N, Asselbergs FW, Kostovska ES, Almaas VM, Biernacka EK, Brito D, Rosca M, Zavatta M, Ristic A, Goncalvesová E, Šinkovec M, Cañadas-Godoy V, Platonov PG, Saguner AM, Saadi ARA, Kammoun I, Celik A, Nesukay E, Abdullaev T, Prescott E, James S, Arbelo E, Baigent C, Borger MA, Buccheri S, Ibanez B, Køber L, Koskinas KC, McEvoy JW, Mihaylova B, Mindham R, Neubeck L, Nielsen JC, Pasquet A, Rakisheva A, Rocca B, Rossello X, Vaartjes I, Vrints C, Witkowski A, Zeppenfeld K (2023) 2023 ESC Guidelines for the management of cardiomyopathies. Eur Heart J 44:3503–3626. https://doi.org/10.1093/eurheartj/ehad194

Article  CAS  Google Scholar 

Ariga R, Tunnicliffe EM, Manohar SG, Mahmod M, Raman B, Piechnik SK, Francis JM, Robson MD, Neubauer S, Watkins H (2019) Identification of myocardial disarray in patients with hypertrophic cardiomyopathy and ventricular arrhythmias. J Am Coll Cardiol 73:2493–2502. https://doi.org/10.1016/j.jacc.2019.02.065

Article  PubMed  PubMed Central  Google Scholar 

Bates J, Teh I, McClymont D, Kohl P, Schneider JE, Grau V (2017) Monte Carlo simulations of diffusion weighted MRI in myocardium: validation and sensitivity analysis. IEEE Trans Med Imaging 36:1316–1325. https://doi.org/10.1109/TMI.2017.2679809

Article  PubMed  Google Scholar 

Berry DB, Regner B, Galinsky V, Ward SR, Frank LR (2018) Relationships between tissue microstructure and the diffusion tensor in simulated skeletal muscle. Magn Reson Med 80:317–329. https://doi.org/10.1002/mrm.26993

Article  PubMed  Google Scholar 

Beyhoff N, Lohr D, Foryst-Ludwig A, Klopfleisch R, Brix S, Grune J, Thiele A, Erfinanda L, Tabuchi A, Kuebler WM, Pieske B, Schreiber LM, Kintscher U (2019) Characterization of myocardial microstructure and function in an experimental model of isolated subendocardial damage. Hypertension 74:295–304. https://doi.org/10.1161/HYPERTENSIONAHA.119.12956

Article  CAS  PubMed  Google Scholar 

Bloom MW, Hamo CE, Cardinale D, Ky B, Nohria A, Baer L, Skopicki H, Lenihan DJ, Gheorghiade M, Lyon AR, Butler J (2016) Cancer therapy-related cardiac dysfunction and heart failure: part 1: definitions, pathophysiology, risk factors, and imaging. Circ Heart Fail 9:e002661. https://doi.org/10.1161/CIRCHEARTFAILURE.115.002661

Article  PubMed  PubMed Central  Google Scholar 

Carruth ED, Teh I, Schneider JE, McCulloch AD, Omens JH, Frank LR (2020) Regional variations in ex-vivo diffusion tensor anisotropy are associated with cardiomyocyte remodeling in rats after left ventricular pressure overload. J Cardiovasc Magn Reson 22:21. https://doi.org/10.1186/s12968-020-00615-1

Article  PubMed  PubMed Central  Google Scholar 

Coelho-Filho OR, Shah RV, Mitchell R, Neilan TG, Moreno H, Simonson B, Kwong R, Rosenzweig A, Das S, Jerosch-Herold M (2013) Quantification of cardiomyocyte hypertrophy by cardiac magnetic resonance: implications for early cardiac remodeling. Circulation 128:1225–1233. https://doi.org/10.1161/CIRCULATIONAHA.112.000438

Article  CAS  PubMed  PubMed Central  Google Scholar 

von Deuster C, Sammut E, Asner L, Nordsletten D, Lamata P, Stoeck CT, Kozerke S, Razavi R (2016) Studying dynamic myofiber aggregate reorientation in dilated cardiomyopathy using in vivo magnetic resonance diffusion tensor imaging. Circ Cardiovasc Imaging 9:e005018. https://doi.org/10.1161/CIRCIMAGING.116.005018

Article  Google Scholar 

Ennis DB, Kindlman G, Rodriguez I, Helm PA, McVeigh ER (2005) Visualization of tensor fields using superquadric glyphs. Magn Reson Med 53:169–176. https://doi.org/10.1002/mrm.20318

Article  PubMed  PubMed Central  Google Scholar 

Ewer MS, Ewer SM (2015) Cardiotoxicity of anticancer treatments. Nat Rev Cardiol 12:547–558. https://doi.org/10.1038/nrcardio.2015.65

Article  CAS  PubMed  Google Scholar 

Farzi M, Coveney S, Afzali M, Zdora M, Lygate CA, Rau C, Frangi AF, Dall’Armellina E, Teh I, Schneider JE (2023) Measuring cardiomyocyte cellular characteristics in cardiac hypertrophy using diffusion-weighted MRI. Magn Reson Med 90:2144–2157. https://doi.org/10.1002/mrm.29775

Article  CAS  PubMed  Google Scholar 

Ferreira de Souza T, Quinaglia A.C. Silva T, Osorio Costa F, Shah R, Neilan TG, Velloso L, Nadruz W, Brenelli F, Sposito AC, Matos-Souza JR, Cendes F, Coelho OR, Jerosch-Herold M, Coelho-Filho OR (2018) Anthracycline therapy is associated with cardiomyocyte atrophy and preclinical manifestations of heart disease. JACC Cardiovasc Imaging 11:1045–1055. https://doi.org/10.1016/j.jcmg.2018.05.012

Article  PubMed  Google Scholar 

Ferreira PF, Kilner PJ, McGill L-A, Nielles-Vallespin S, Scott AD, Ho SY, McCarthy KP, Haba MM, Ismail TF, Gatehouse PD, de Silva R, Lyon AR, Prasad SK, Firmin DN, Pennell DJ (2014) In vivo cardiovascular magnetic resonance diffusion tensor imaging shows evidence of abnormal myocardial laminar orientations and mobility in hypertrophic cardiomyopathy. J Cardiovasc Magn Reson 16:87. https://doi.org/10.1186/s12968-014-0087-8

Article  PubMed  PubMed Central  Google Scholar 

Gotschy A, Von Deuster C, Van Gorkum RJH, Gastl M, Vintschger E, Schwotzer R, Flammer AJ, Manka R, Stoeck CT, Kozerke S (2019) Characterizing cardiac involvement in amyloidosis using cardiovascular magnetic resonance diffusion tensor imaging. J Cardiovasc Magn Reson 21:56. https://doi.org/10.1186/s12968-019-0563-2

Article  PubMed  PubMed Central  Google Scholar 

Gotschy A, Von Deuster C, Weber L, Gastl M, Schmiady MO, Van Gorkum RJH, Stimm J, Von Spiczak J, Manka R, Kozerke S, Stoeck CT (2021) CMR diffusion tensor imaging provides novel imaging markers of adverse myocardial remodeling in aortic stenosis. JACC Cardiovasc Imaging 14:1472–1474. https://doi.org/10.1016/j.jcmg.2020.12.026

Article  PubMed  Google Scholar 

Gupta SK, Garg A, Bär C, Chatterjee S, Foinquinos A, Milting H, Streckfuß-Bömeke K, Fiedler J, Thum T (2018) Quaking inhibits doxorubicin-mediated cardiotoxicity through regulation of cardiac circular RNA expression. Circ Res 122:246–254. https://doi.org/10.1161/CIRCRESAHA.117.311335

Article  CAS  PubMed  Google Scholar 

Herrmann J (2020) Adverse cardiac effects of cancer therapies: cardiotoxicity and arrhythmia. Nat Rev Cardiol 17:474–502. https://doi.org/10.1038/s41569-020-0348-1

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hochmann S, Ou K, Poupardin R, Mittermeir M, Textor M, Ali S, Wolf M, Ellinghaus A, Jacobi D, Elmiger JAJ, Donsante S, Riminucci M, Schäfer R, Kornak U, Klein O, Schallmoser K, Schmidt-Bleek K, Duda GN, Polansky JK, Geissler S, Strunk D (2023) The enhancer landscape predetermines the skeletal regeneration capacity of stromal cells. Sci Transl Med 15:eabm7477. https://doi.org/10.1126/scitranslmed.abm7477

Article  CAS  PubMed  Google Scholar 

Jordan JH, Castellino SM, Meléndez GC, Klepin HD, Ellis LR, Lamar Z, Vasu S, Kitzman DW, Ntim WO, Brubaker PH, Reichek N, D’Agostino RB, Hundley WG (2018) Left Ventricular Mass Change After Anthracycline Chemotherapy. Circ Heart Fail 11:e004560. https://doi.org/10.1161/CIRCHEARTFAILURE.117.004560

Article  CAS  PubMed  PubMed Central  Google Scholar 

Khalique Z, Ferreira PF, Scott AD, Nielles-Vallespin S, Firmin DN, Pennell DJ (2020) Diffusion tensor cardiovascular magnetic resonance imaging. JACC Cardiovasc Imaging 13:1235–1255. https://doi.org/10.1016/j.jcmg.2019.07.016

Article  PubMed  Google Scholar 

Lena A, Wilkenshoff U, Hadzibegovic S, Porthun J, Rösnick L, Fröhlich A-K, Zeller T, Karakas M, Keller U, Ahn J, Bullinger L, Riess H, Rosen SD, Lyon AR, Lüscher TF, Totzeck M, Rassaf T, Burkhoff D, Mehra MR, Bax JJ, Butler J, Edelmann F, Haverkamp W, Anker SD, Packer M, Coats AJS, Von Haehling S, Landmesser U, Anker MS (2023) Clinical and prognostic relevance of cardiac wasting in patients with advanced cancer. J Am Coll Cardiol 81:1569–1586. https://doi.org/10.1016/j.jacc.2023.02.039

Article  PubMed  Google Scholar 

Lipshultz SE, Colan SD, Gelber RD, Perez-Atayde AR, Sallan SE, Sanders SP (1991) Late cardiac effects of doxorubicin therapy for acute lymphoblastic leukemia in childhood. N Engl J Med 324:808–815. https://doi.org/10.1056/NEJM199103213241205

Article  CAS  PubMed  Google Scholar 

Lohr D, Terekhov M, Veit F, Schreiber LM (2020) Longitudinal assessment of tissue properties and cardiac diffusion metrics of the ex vivo porcine heart at 7 T: impact of continuous tissue fixation using formalin. NMR Biomed 33:e4298. https://doi.org/10.1002/nbm.4298

Article  CAS  PubMed  Google Scholar 

Lohr D, Thiele A, Stahnke M, Braun V, Smeir E, Spranger J, Brachs S, Klopfleisch R, Foryst-Ludwig A, Schreiber LM, Kintscher U, Beyhoff N (2022) Assessment of myocardial microstructure in a murine model of obesity-related cardiac dysfunction by diffusion tensor magnetic resonance imaging at 7T. Front Cardiovasc Med 9:839714. https://doi.org/10.3389/fcvm.2022.839714

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lyon AR, López-Fernández T, Couch LS, Asteggiano R, Aznar MC, Bergler-Klein J, Boriani G, Cardinale D, Cordoba R, Cosyns B, Cutter DJ, de Azambuja E, de Boer RA, Dent SF, Farmakis D, Gevaert SA, Gorog DA, Herrmann J, Lenihan D, Moslehi J, Moura B, Salinger SS, Stephens R, Suter TM, Szmit S, Tamargo J, Thavendiranathan P, Tocchetti CG, van der Meer P, van der Pal HJH, ESC Scientific Document Group, Lancellotti P, Thuny F, Abdelhamid M, Aboyans V, Aleman B, Alexandre J, Barac A, Borger MA, Casado-Arroyo R, Cautela J, Čelutkienė J, Cikes M, Cohen-Solal A, Dhiman K, Ederhy S, Edvardsen T, Fauchier L, Fradley M, Grapsa J, Halvorsen S, Heuser M, Humbert M, Jaarsma T, Kahan T, Konradi A, Koskinas KC, Kotecha D, Ky B, Landmesser U, Lewis BS, Linhart A, Lip GYH, Løchen ML, Malaczynska-Rajpold K, Metra M, Mindham R, Moonen M, Neilan TG, Nielsen JC, Petronio AS, Prescott E, Rakisheva A, Salem JE, Savarese G, Sitges M, ten Berg J, Touyz RM, Tycinska A, Wilhelm M, Zamorano JL, Laredj N, Zelveian P, Rainer PP, Samadov F, Andrushchuk U, Gerber BL, Selimović M, Kinova E, Samardzic J, Economides E, Pudil R, Nielsen KM, Kafafy TA, Vettus R, Tuohinen S, Ederhy S, Pagava Z, Rassaf T, Briasoulis A, Czuriga D, Andersen KK, Smyth Y, Iakobishvili Z, Parrini I, Rakisheva A, Pruthi EP, Mirrakhimov E, Kalejs O, Skouri H, Benlamin H, Žaliaduonytė D, Iovino A, Moore AM, Bursacovschi D, Benyass A, Manintveld O, Bosevski M, Gulati G, Leszek P, Fiuza M, Jurcut R, Vasyuk Y, Foscoli M, Simic D, Slanina M, Lipar L, Martin-Garcia A, Hübbert L, Kurmann R, Alayed A, Abid L, Zorkun C, Nesukay E, Manisty C, Srojidinova N (2022) 2022 ESC guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS). Eur Heart J 43:4229–4361. https://doi.org/10.1093/eurheartj/ehac244

Article  Google Scholar 

Murphy KT (2016) The pathogenesis and treatment of cardiac atrophy in cancer cachexia. Am J Physiol Heart Circ Physiol 310:H466–H477. https://doi.org/10.1152/ajpheart.00720.2015

Article  PubMed  Google Scholar 

Neilan TG, Coelho-Filho OR, Pena-Herrera D, Shah RV, Jerosch-Herold M, Francis SA, Moslehi J, Kwong RY (2012) Left ventricular mass in patients with a cardiomyopathy after t

留言 (0)

沒有登入
gif