Immune profiles of pre-frail people living with HIV-1: a prospective longitudinal study

Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol Biol Sci Med Sci. 2001;56(3):M146–56.

Article  CAS  Google Scholar 

Kooij KW, Wit FW, Schouten J, van der Valk M, Godfried MH, Stolte IG, et al. HIV infection is independently associated with frailty in middle-aged HIV type 1-infected individuals compared with similar but uninfected controls. AIDS. 2016;30(2):241–50.

Article  CAS  PubMed  Google Scholar 

Justice AC, Freiberg MS, Tracy R, Kuller L, Tate JP, Goetz MB, et al. Does an index composed of clinical data reflect effects of inflammation, coagulation, and monocyte activation on mortality among those aging with HIV? Clin Infect Dis. 2012;54(7):984–94.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Guaraldi G, Brothers TD, Zona S, Stentarelli C, Carli F, Malagoli A, et al. A frailty index predicts survival and incident multimorbidity independent of markers of HIV disease severity. AIDS. 2015;29(13):1633–41.

Article  PubMed  Google Scholar 

Allavena C, Blain H, Abulizi X, Slama L, Katlama C, Delobel P, et al. Prevalence and risk factors of frailty among adults living with HIV aged 70 years or older. AIDS. 2023;37(1):183–9.

Article  PubMed  Google Scholar 

Althoff KN, Jacobson LP, Cranston RD, Detels R, Phair JP, Li X, et al. Age, comorbidities, and AIDS predict a frailty phenotype in men who have sex with men. J Gerontol Biol Sci Med Sci. 2014;69(2):189–98.

Article  Google Scholar 

Erlandson KM, Allshouse AA, Jankowski CM, Lee EJ, Rufner KM, Palmer BE, et al. Association of functional impairment with inflammation and immune activation in HIV type 1-infected adults receiving effective antiretroviral therapy. J Infect Dis. 2013;208(2):249–59.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Onen NF, Agbebi A, Shacham E, Stamm KE, Onen AR, Overton ET. Frailty among HIV-infected persons in an urban outpatient care setting. J Infect. 2009;59(5):346–52.

Article  PubMed  Google Scholar 

Piggott DA, Muzaale AD, Mehta SH, Brown TT, Patel KV, Leng SX, et al. Frailty, HIV infection, and mortality in an aging cohort of injection drug users. PLoS ONE. 2013;8(1):e54910.

Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

Erlandson KM, Allshouse AA, Jankowski CM, Duong S, Mawhinney S, Kohrt WM, et al. Comparison of functional status instruments in HIV-infected adults on effective antiretroviral therapy. HIV Clin Trials. 2012;13(6):324–34.

Article  PubMed  PubMed Central  Google Scholar 

Terzian AS, Holman S, Nathwani N, Robison E, Weber K, Young M, et al. Factors associated with preclinical disability and frailty among HIV-infected and HIV-uninfected women in the era of cART. J Womens Health (Larchmt). 2009;18(12):1965–74.

Article  PubMed  Google Scholar 

Yeoh HL, Cheng AC, Cherry CL, Weir JM, Meikle PJ, Hoy JF, et al. Immunometabolic and lipidomic markers Associated with the Frailty Index and Quality of Life in Aging HIV + Men on antiretroviral therapy. EBioMedicine. 2017;22:112–21.

Article  PubMed  PubMed Central  Google Scholar 

Erlandson KM, Allshouse AA, Jankowski CM, MaWhinney S, Kohrt WM, Campbell TB. Functional impairment is associated with low bone and muscle mass among persons aging with HIV infection. J Acquir Immune Defic Syndr. 2013;63(2):209–15.

Article  PubMed  PubMed Central  Google Scholar 

Masters MC, Perez J, Wu K, Ellis RJ, Goodkin K, Koletar SL, et al. Baseline neurocognitive impairment (NCI) is Associated With Incident Frailty but Baseline Frailty does not Predict Incident NCI in older persons with Human Immunodeficiency Virus (HIV). Clin Infect Dis. 2021;73(4):680–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ianas V, Berg E, Mohler MJ, Wendel C, Klotz SA. Antiretroviral therapy protects against frailty in HIV-1 infection. J Int Assoc Provid AIDS Care. 2013;12(1):62–6.

Article  PubMed  Google Scholar 

Pathai S, Gilbert C, Weiss HA, Cook C, Wood R, Bekker LG, et al. Frailty in HIV-infected adults in South Africa. J Acquir Immune Defic Syndr. 2013;62(1):43–51.

Article  PubMed  PubMed Central  Google Scholar 

Fulop T, Witkowski JM, Olivieri F, Larbi A. The integration of inflammaging in age-related diseases. Semin Immunol. 2018;40:17–35.

Article  CAS  PubMed  Google Scholar 

Nazmi A, Victora CG. Socioeconomic and racial/ethnic differentials of C-reactive protein levels: a systematic review of population-based studies. BMC Public Health. 2007;7:212.

Article  PubMed  PubMed Central  Google Scholar 

Halaris A. Co-morbidity between cardiovascular pathology and depression: role of inflammation. Mod Trends Pharmacopsychiatry. 2013;28:144–61.

Article  CAS  PubMed  Google Scholar 

Younas M, Psomas C, Reynes J, Corbeau P. Immune activation in the course of HIV-1 infection: causes, phenotypes and persistence under therapy. HIV Med. 2016;17:89–105.

Article  CAS  PubMed  Google Scholar 

Margolick JB, Bream JH, Martinez-Maza O, Lopez J, Li X, Phair JP, et al. Frailty and circulating markers of inflammation in HIV + and HIV- Men in the Multicenter AIDS Cohort Study. J Acquir Immune Defic Syndr. 2017;74(4):407–17.

Article  PubMed  PubMed Central  Google Scholar 

Piggott DA, Varadhan R, Mehta SH, Brown TT, Li H, Walston JD, et al. Frailty, inflammation, and Mortality among persons Aging with HIV infection and Injection Drug Use. J Gerontol Biol Sci Med Sci. 2015;70(12):1542–7.

Article  CAS  Google Scholar 

Leng S, Chaves P, Koenig K, Walston J. Serum interleukin-6 and hemoglobin as physiological correlates in the geriatric syndrome of frailty: a pilot study. J Am Geriatr Soc. 2002;50(7):1268–71.

Article  PubMed  Google Scholar 

Margolick JB, Bream JH, Nilles TL, Li H, Langan SJ, Deng S, et al. Relationship between T-Cell responses to CMV, markers of inflammation, and Frailty in HIV-uninfected and HIV-infected men in the Multicenter AIDS Cohort Study. J Infect Dis. 2018;218(2):249–58.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Derry HM, Johnston CD, Burchett CO, Brennan-Ing M, Karpiak S, Zhu YS, et al. Links between inflammation, Mood, and physical function among older adults with HIV. J Gerontol B Psychol Sci Soc Sci. 2022;77(1):50–60.

Article  PubMed  Google Scholar 

Hamilton GF, McDonald C, Chenier TC. Measurement of grip strength: validity and reliability of the sphygmomanometer and jamar grip dynamometer. J Orthop Sports Phys Ther. 1992;16(5):215–9.

Article  CAS  PubMed  Google Scholar 

Lee PH, Macfarlane DJ, Lam TH, Stewart SM. Validity of the International Physical Activity Questionnaire Short Form (IPAQ-SF): a systematic review. Int J Behav Nutr Phys Act. 2011;8:115.

Article  PubMed  PubMed Central  Google Scholar 

Raho-Moussa M, Guiguet M, Michaud C, Honore P, Palacios C, Boue F, et al. Respective roles of migration and social deprivation for virological non-suppression in HIV-infected adults on antiretroviral therapy in France. PLoS ONE. 2019;14(3):e0213019.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cezar R, Winter A, Desigaud D, Pastore M, Kundura L, Dupuy A-M, et al. Identification of distinct immune activation profiles in adult humans. Sci Rep. 2020;10(1):20824.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cezar R, Desigaud D, Pastore M, Kundura L, Dupuy AM, Cognot C, et al. Insulin resistance is linked to a specific profile of immune activation in human subjects. Sci Rep. 2021;11(1):12314.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Soysal P, Stubbs B, Lucato P, Luchini C, Solmi M, Peluso R, et al. Inflammation and frailty in the elderly: a systematic review and meta-analysis. Ageing Res Rev. 2016;31:1–8.

Article  CAS  PubMed  Google Scholar 

Puzianowska-Kuznicka M, Owczarz M, Wieczorowska-Tobis K, Nadrowski P, Chudek J, Slusarczyk P, et al. Interleukin-6 and C-reactive protein, successful aging, and mortality: the PolSenior study. Immun Ageing. 2016;13:21.

Article  PubMed  PubMed Central  Google Scholar 

Walker KA, Hoogeveen RC, Folsom AR, Ballantyne CM, Knopman DS, Windham BG, et al. Midlife systemic inflammatory markers are associated with late-life brain volume: the ARIC study. Neurology. 2017;89(22):2262–70.

Article  PubMed  PubMed Central  Google Scholar 

De Fanis U, Wang GC, Fedarko NS, Walston JD, Casolaro V, Leng SX. T-lymphocytes expressing CC chemokine receptor-5 are increased in frail older adults. J Am Geriatr Soc. 2008;56(5):904–8.

Article  PubMed  PubMed Central  Google Scholar 

Wang GC, Casolaro V. Immunologic changes in frail older adults. Transl Med UniSa. 2014;9:1–6.

PubMed  PubMed Central  Google Scholar 

Johnstone J, Parsons R, Botelho F, Millar J, McNeil S, Fulop T

留言 (0)

沒有登入
gif