Advances in Proton Therapy for the Management of Head and Neck Tumors

Wilson R.R.

Radiological use of fast protons.

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A Multi-institutional Comparative Analysis of Proton and Photon Therapy-Induced Hematologic Toxicity in Patients With Medulloblastoma.

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The benefits and pitfalls of ipsilateral radiotherapy in carcinoma of the tonsillar region.

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Radiotherapy for early glottic carcinoma (T1N0M0): results of prospective randomized study of radiation fraction size and overall treatment time.

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Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer.

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Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck.

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Defining risk levels in locally advanced head and neck cancers: a comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501).

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Increased risk of ischemic stroke after radiotherapy on the neck in patients younger than 60 years.

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Objective assessment of swallowing dysfunction and aspiration after radiation concurrent with chemotherapy for head-and-neck cancer.

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Quality of life after parotid-sparing IMRT for head-and-neck cancer: a prospective longitudinal study.

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Cerebrovascular disease risk in older head and neck cancer patients after radiotherapy.

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Hypothyroidism in older patients with head and neck cancer after treatment with radiation: a population-based study.

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Osteoradionecrosis and radiation dose to the mandible in patients with oropharyngeal cancer.

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Risk of fatal cerebrovascular accidents after external beam radiation therapy for early-stage glottic laryngeal cancer.

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Epidemiology of Human Papillomavirus-Positive Head and Neck Squamous Cell Carcinoma.

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Human papillomavirus and rising oropharyngeal cancer incidence in the United States.

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Human papillomavirus and survival of patients with oropharyngeal cancer.

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PTCOG Head and Neck Subcommittee Consensus Guidelines on Particle Therapy for the Management of Head and Neck Tumors.

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Acute toxicity in comprehensive head and neck radiation for nasopharynx and paranasal sinus cancers: cohort comparison of 3D conformal proton therapy and intensity modulated radiation therapy.

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Proton Therapy Reduces Treatment-Related Toxicities for Patients with Nasopharyngeal Cancer: A Case-Match Control Study of Intensity-Modulated Proton Therapy and Intensity-Modulated Photon Therapy.

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Outcomes of Sinonasal Cancer Treated With Proton Therapy.

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Long-Term Outcomes After Proton Beam Therapy for Sinonasal Squamous Cell Carcinoma.

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Charged particle therapy versus photon therapy for paranasal sinus and nasal cavity malignant diseases: a systematic review and meta-analysis.

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Intensity-modulated proton beam therapy (IMPT) versus intensity-modulated photon therapy (IMRT) for patients with oropharynx cancer - A case matched analysis.

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Quality of Life of Postoperative Photon versus Proton Radiation Therapy for Oropharynx Cancer.

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MD Anderson Cancer Center. Randomized trial of intensity-modulated proton beam therapy (IMPT) versus intensitymodulated photon therapy (IMRT) for the treatment of oropharyngeal cancer of the head and neck. ClinicalTrials.gov Identifier: NCT01893307. Available at: https://clinicaltrials.gov/ct2/show/NCT01893307. Accessed February 14, 2023.

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TORPEdO: A phase III trial of intensity-modulated proton beam therapy versus intensity-modulated radiotherapy for multi-toxicity reduction in oropharyngeal cancer.

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Proton beam radiation therapy results in significantly reduced toxicity compared with intensity-modulated radiation therapy for head and neck tumors that require ipsilateral radiation.

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Reirradiation of Head and Neck Cancers With Proton Therapy: Outcomes and Analyses.

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Reirradiation of Recurrent and Second Primary Head and Neck Cancer With Proton Therapy.

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Proton Beam Reirradiation for Recurrent Head and Neck Cancer: Multi-institutional Report on Feasibility and Early Outcomes.

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Proton beam therapy and accountable care: the challenges ahead.

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Proton radiation therapy for chordomas and chondrosarcomas of the skull base.

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Budget impact analysis.

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Proton Facility Economics: Single-Room Centers.

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Proton facility economics: the importance of "simple" treatments.

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Beyond a moonshot: insurance coverage for proton therapy.

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Randomized Trials of Proton Therapy: Why They Are at Risk, Proposed Solutions, and Implications for Evaluating Advanced Technologies to Diagnose and Treat Cancer.

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The Insurance Approval Process for Proton Radiation Therapy: A Significant Barrier to Patient Care.

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Insurance Approval for Proton Beam Therapy and its Impact on Delays in Treatment.

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A systematic review of the cost and cost-effectiveness studies of proton radiotherapy.

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