1.
Olah, J., Orosz, F., Keseru, G. M., et al. Triosephosphate Isomerase Deficiency: A Neurodegenerative Misfolding Disease. Biochem. Soc. Trans. 2002, 30, 30–38.
Google Scholar |
Crossref |
Medline2.
Orosz, F., Olah, J., Ovadi, J. Triosephosphate Isomerase Deficiency: Facts and Doubts. IUBMB Life 2006, 58, 703–715.
Google Scholar |
Crossref |
Medline3.
Fogle, K. J., Smith, A. R., Satterfield, S. L., et al. Ketogenic and Anaplerotic Dietary Modifications Ameliorate Seizure Activity in Drosophila Models of Mitochondrial Encephalomyopathy and Glycolytic Enzymopathy. Mol. Genet. Metab. 2019, 126, 439–447.
Google Scholar |
Crossref |
Medline4.
Knowles, J. R., Albery, W. J. Perfection in Enzyme Catalysis: The Energetics of Triosephosphate Isomerase. Acc. Chem. Res. 1977, 10, 105–111.
Google Scholar |
Crossref5.
Roland, B. P., Richards, K. R., Hrizo, S. L., et al. Missense Variant in TPI1 (Arg189Gln) Causes Neurologic Deficits through Structural Changes in the Triosephosphate Isomerase Catalytic Site and Reduced Enzyme Levels In Vivo. Biochim. Biophys. Acta Mol. Basis Dis. 2019, 1865, 2257–2266.
Google Scholar |
Crossref |
Medline6.
Ralser, M., Heeren, G., Breitenbach, M., et al. Triose Phosphate Isomerase Deficiency Is Caused by Altered Dimerization—Not Catalytic Inactivity—of the Mutant Enzymes. PLOS ONE 2006, 1, e30.
Google Scholar |
Crossref |
Medline7.
Seigle, J. L., Celotto, A. M., Palladino, M. J. Degradation of Functional Triose Phosphate Isomerase Protein Underlies Sugarkill Pathology. Genetics 2008, 179, 855–862.
Google Scholar |
Crossref |
Medline8.
Hrizo, S. L., Palladino, M. J. Hsp70- and Hsp90-Mediated Proteasomal Degradation Underlies TPI Sugarkill Pathogenesis in Drosophila. Neurobiol. Dis. 2010, 40, 676–683.
Google Scholar |
Crossref |
Medline9.
Celotto, A. M., Frank, A. C., Seigle, J. L., et al. Drosophila Model of Human Inherited Triosephosphate Isomerase Deficiency Glycolytic Enzymopathy. Genetics 2006, 174, 1237–1246.
Google Scholar |
Crossref |
Medline10.
Genest, O., Wickner, S., Doyle, S. M. Hsp90 and Hsp70 Chaperones: Collaborators in Protein Remodeling. J. Biol. Chem. 2019, 294, 2109–2120.
Google Scholar |
Crossref |
Medline11.
Hrizo, S. L., Eicher, S. L., Myers, T. D., et al. Identification of Protein Quality Control Regulators Using a Drosophila Model of TPI Deficiency. Neurobiol. Dis. 2021, 152, 105299.
Google Scholar |
Crossref |
Medline12.
Lane, S. J., Eggleston, D. S., Brinded, K. A., et al. Defining and Maintaining a High Quality Screening Collection: The GSK Experience. Drug Discov. Today 2006, 11, 267–272.
Google Scholar |
Crossref |
Medline13.
Blaxill, Z., Holland-Crimmin, S., Lifely, R. Stability through the Ages: The GSK Experience. J. Biomol. Screen. 2009, 14, 547–556.
Google Scholar |
SAGE Journals14.
Kaur, M., Esau, L. Two-Step Protocol for Preparing Adherent Cells for High-Throughput Flow Cytometry. Biotechniques 2015, 59, 119–126.
Google Scholar |
Crossref |
Medline15.
Iversen, P. W., Beck, B., Chen, Y. F., et al. HTS Assay Validation. In Assay Guidance Manual; Sittampalam, G. S., Coussens, N. P., Brimacombe, K., et al., Eds.; Eli Lilly & Company and the National Center for Advancing Translational Sciences: Bethesda (MD), 2004.
Google Scholar16.
Rodriguez-Almazan, C., Arreola, R., Rodriguez-Larrea, D., et al. Structural Basis of Human Triosephosphate Isomerase Deficiency: Mutation E104D Is Related to Alterations of a Conserved Water Network at the Dimer Interface. J. Biol. Chem. 2008, 283, 23254–23263.
Google Scholar |
Crossref |
Medline17.
Roland, B. P., Amrich, C. G., Kammerer, C. J., et al. Triosephosphate Isomerase I170V Alters Catalytic Site, Enhances Stability and Induces Pathology in a Drosophila Model of TPI Deficiency. Biochim. Biophys. Acta 2015, 1852, 61–69.
Google Scholar |
Crossref |
Medline18.
Roland, B. P., Zeccola, A. M., Larsen, S. B., et al. Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics. PLoS Genet. 2016, 12, e1005941.
Google Scholar |
Crossref |
Medline19.
Vogt, A., Lazo, J. S. Discovery of Protein Kinase Phosphatase Inhibitors. Methods Mol. Biol. 2007, 356, 389–400.
Google Scholar |
Medline20.
Joy, M. E., Vollmer, L. L., Hulkower, K., et al. A High-Content, Multiplexed Screen in Human Breast Cancer Cells Identifies Profilin-1 Inducers with Anti-Migratory Activities. PLOS ONE 2014, 9, e88350.
Google Scholar |
Crossref21.
Poe, J. A., Vollmer, L., Vogt, A., et al. Development and Validation of a High-Content Bimolecular Fluorescence Complementation Assay for Small-Molecule Inhibitors of HIV-1 Nef Dimerization. J. Biomol. Screen. 2014, 19, 556–565.
Google Scholar |
SAGE Journals22.
Nmezi, B., Vollmer, L. L., Shun, T. Y., et al. Development and Optimization of a High-Content Analysis Platform to Identify Suppressors of Lamin B1 Overexpression as a Therapeutic Strategy for Autosomal Dominant Leukodystrophy. SLAS Discov. 2020, 2472555220915821.
Google Scholar23.
Zhang, J. H., Chung, T. D. Y., Oldenburg, K. R. A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays. J. Biomol. Screen. 1999, 4, 67–73.
Google Scholar |
SAGE Journals24.
Alway, S. E., McCrory, J. L., Kearcher, K., et al. Resveratrol Enhances Exercise-Induced Cellular and Functional Adaptations of Skeletal Muscle in Older Men and Women. J. Gerontol. A Biol. Sci. Med. Sci. 2017, 72, 1595–1606.
Google Scholar |
Crossref |
Medline25.
Haramizu, S., Asano, S., Butler, D. C., et al. Dietary Resveratrol Confers Apoptotic Resistance to Oxidative Stress in Myoblasts. J. Nutr. Biochem. 2017, 50, 103–115.
Google Scholar |
Crossref26.
Hrizo, S. L., Fisher, I. J., Long, D. R., et al. Early Mitochondrial Dysfunction Leads to Altered Redox Chemistry Underlying Pathogenesis of TPI Deficiency. Neurobiol. Dis. 2013, 54, 289–296.
Google Scholar |
Crossref |
Medline27.
Forouzanfar, F., Butler, A. E., Banach, M., et al. Modulation of Heat Shock Proteins by Statins. Pharmacol. Res. 2018, 134, 134–144.
Google Scholar |
Crossref |
Medline28.
Luo, Z., Zhang, Y., Gu, J., et al. Pharmacokinetic Properties of Single- and Multiple-Dose Pitavastatin Calcium Tablets in Healthy Chinese Volunteers. Curr. Ther. Res. Clin. Exp. 2015, 77, 52–57.
Google Scholar |
Crossref |
Medline
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