Daniela L. Chronic critical illness. N Engl J Med. 2014;370(2):175–7.

Article  Google Scholar 

Nelson JE, Cox CE, Hope AA, Carson SS. Chronic critical illness. Am J Respir Crit Care Med. 2010;182(4):446–54.

Article  PubMed  PubMed Central  Google Scholar 

Chadda KR, Puthucheary Z. Persistent inflammation, immunosuppression, and catabolism syndrome (PICS): a review of definitions, potential therapies, and research priorities. Br J Anaesth. 2024;132(3):507–18.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zilberberg MD, de Wit M, Pirone JR, Shorr AF. Growth in adult prolonged acute mechanical ventilation: implications for healthcare delivery. Crit Care Med. 2008;36(5):1451–5.

Article  PubMed  Google Scholar 

Sjoding MW, Cooke CR. Chronic critical illness: a growing legacy of successful advances in critical care. Crit Care Med. 2015;43(2):476–7.

Article  PubMed  PubMed Central  Google Scholar 

Rosenthal MD, Vanzant EL, Moore FA. Chronic critical illness and PICS nutritional strategies. J Clin Med Res. 2021;10(11):2294. https://doi.org/10.3390/jcm10112294.

Article  CAS  Google Scholar 

Rousseau AF, Prescott HC, Brett SJ, et al. Long-term outcomes after critical illness: recent insights. Crit Care. 2021;25(1):108.

Article  PubMed  PubMed Central  Google Scholar 

Hawkins RB, Raymond SL, Stortz JA, et al. Chronic critical illness and the persistent inflammation, immunosuppression, and catabolism syndrome. Front Immunol. 2018;9:1511.

Article  PubMed  PubMed Central  Google Scholar 

Voiriot G, Oualha M, Pierre A, et al. Chronic critical illness and post-intensive care syndrome: from pathophysiology to clinical challenges. Ann Intensive Care. 2022;12(1):58.

Article  PubMed  PubMed Central  Google Scholar 

Wiencek C, Winkelman C. Chronic critical illness: prevalence, profile, and pathophysiology. AACN Adv Crit Care. 2010;21(1):44–61.

PubMed  Google Scholar 

Madrid RA, McGee W. Value, chronic critical illness, and choosing wisely. J Intensive Care Med. 2019;34(8):609–14.

Article  PubMed  Google Scholar 

Marchioni A, Fantini R, Antenora F, Clini E, Fabbri L. Chronic critical illness: the price of survival. Eur J Clin Invest. 2015;45(12):1341–9.

Article  PubMed  Google Scholar 

Rosenthal MD, Kamel AY, Rosenthal CM, Brakenridge S, Croft CA, Moore FA. Chronic critical illness: application of what we know. Nutr Clin Pract. 2018;33(1):39–45.

Article  PubMed  PubMed Central  Google Scholar 

Tricco AC, Lillie E, Zarin W, et al. PRISMA extension for Scoping Reviews (PRISMA-ScR): checklist and explanation. Ann Intern Med. 2018;169(7):467–73.

Article  PubMed  Google Scholar 

Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A. Rayyan-a web and mobile app for systematic reviews. Syst Rev. 2016;5(1):210.

Article  PubMed  PubMed Central  Google Scholar 

Lenzen SA, Daniëls R, van Bokhoven MA, van der Weijden T, Beurskens A. Disentangling self-management goal setting and action planning: a scoping review. PLoS ONE. 2017;12(11):e0188822.

Article  PubMed  PubMed Central  Google Scholar 

Nyaga VN, Arbyn M, Aerts M. Metaprop: a Stata command to perform meta-analysis of binomial data. Arch Public Health. 2014;72(1):39.

Article  PubMed  PubMed Central  Google Scholar 

Fisher D, Harris R, Bradburn M, et al. METAN: Stata module for fixed and random effects meta-analysis. Statistical Software Components. S456798, Boston College Department of Economics, revised 15 Jul 2024.

Julian PT Higgins, Tianjing Li, Jonathan J Deeks. Chapter 6: Choosing effect measures and computing estimates of effect. Cochrane Handbook for Systematic Reviews of Interventions version 6.5. Cochrane, 2024. Available from www.training.cochrane.org/handbook.

Nelson JE, Meier DE, Litke A, Natale DA, Siegel RE, Morrison RS. The symptom burden of chronic critical illness. Crit Care Med. 2004;32(7):1527–34.

Article  PubMed  Google Scholar 

Via MA, Potenza MV, Hollander J, et al. Intravenous ibandronate acutely reduces bone hyperresorption in chronic critical illness. J Intensive Care Med. 2012;27(5):312–8.

Article  PubMed  Google Scholar 

Baldwin MR, Wunsch H, Reyfman PA, et al. High burden of palliative needs among older intensive care unit survivors transferred to post-acute care facilities. A single-center study. Ann Am Thorac Soc. 2013;10(5):458–65.

Article  PubMed  PubMed Central  Google Scholar 

Kahn JM, Werner RM, David G, Ten Have TR, Benson NM, Asch DA. Effectiveness of long-term acute care hospitalization in elderly patients with chronic critical illness. Med Care. 2013;51(1):4–10.

Article  PubMed  PubMed Central  Google Scholar 

Loss SH, Marchese CB, Boniatti MM, et al. Prediction of chronic critical illness in a general intensive care unit. Rev Assoc Med Bras. 2013;59(3):241–7.

Article  PubMed  Google Scholar 

Kahn JM, Le T, Angus DC, et al. The epidemiology of chronic critical illness in the United States*. Crit Care Med. 2015;43(2):282–7.

Article  PubMed  PubMed Central  Google Scholar 

Carson SS, Cox CE, Wallenstein S, et al. Effect of palliative care-led meetings for families of patients with chronic critical illness: a randomized clinical trial. JAMA. 2016;316(1):51–62.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mira JC, Cuschieri J, Ozrazgat-Baslanti T, et al. The epidemiology of chronic critical illness after severe traumatic injury at two level-one trauma centers. Crit Care Med. 2017;45(12):1989–96.

Article  PubMed  PubMed Central  Google Scholar 

Brakenridge SC, Efron PA, Stortz JA, et al. The impact of age on the innate immune response and outcomes after severe sepsis/septic shock in trauma and surgical intensive care unit patients. J Trauma Acute Care Surg. 2018;85(2):247–55.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Davoudi A, Corbett DB, Ozrazgat-Baslanti T, et al. Activity and circadian rhythm of sepsis patients in the Intensive Care Unit. IEEE EMBS Int Conf Biomed Health Inform. 2018;2018:17–20.

PubMed  PubMed Central  Google Scholar 

Stortz JA, Murphy TJ, Raymond SL, et al. Evidence for persistent immune suppression in patients who develop chronic critical illness after sepsis. Shock. 2018;49(3):249–58.

Article  PubMed  PubMed Central  Google Scholar 

Stortz JA, Mira JC, Raymond SL, et al. Benchmarking clinical outcomes and the immunocatabolic phenotype of chronic critical illness after sepsis in surgical intensive care unit patients. J Trauma Acute Care Surg. 2018;84(2):342–9.

Article  PubMed  PubMed Central  Google Scholar 

Thomas S, Mehrholz J. Health-related quality of life, participation, and physical and cognitive function of patients with intensive care unit-acquired muscle weakness 1 year after rehabilitation in Germany: the GymNAST cohort study. BMJ Open. 2018;8(7):e020163.

Article  PubMed  PubMed Central  Google Scholar 

Aguiar FP, Westphal GA, Dadam MM, Mota ECC, Pfutzenreuter F, França PHC. Characteristics and predictors of chronic critical illness in the intensive care unit. Rev Bras Ter Intensiva. 2019;31(4):511–20.

Article  PubMed  PubMed Central  Google Scholar 

Brakenridge SC, Moore FA, Mercier NR, et al. Persistently elevated glucagon-like peptide-1 levels among critically ill surgical patients after sepsis and development of chronic critical illness and dismal long-term outcomes. J Am Coll Surg. 2019;229(1):58-67.e1.

Article  PubMed  PubMed Central