VZV IE4 downregulates cellular surface MHC-I via sequestering it to the Golgi complex

Abendroth A, Lin I, Slobedman B, Ploegh H, Arvin AM (2001) Varicella-Zoster virus retains major histocompatibility complex class I proteins in the golgi compartment of infected cells. J Virol 75(10):4878–4888

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cohen JI (1998) Infection of cells with varicella-zoster virus down-regulates surface expression of class I major histocompatibility complex antigens. J Infect Dis 177(5):1390–1393

Article  CAS  PubMed  Google Scholar 

Jones TR, Hanson LK, Sun L, Slater JS, Stenberg RM, Campbell AE (1995) Multiple independent loci within the human cytomegalovirus unique short region down-regulate expression of major histocompatibility complex class I heavy chains. J Virol 69(8):4830–4841

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jones TR, Sun L (1997) Human cytomegalovirus US2 destabilizes major histocompatibility complex class I heavy chains. J Virol 71(4):2970–2979

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jones TR, Wiertz EJ, Sun L, Fish KN, Nelson JA, Ploegh HL (1996) Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains. Proc Natl Acad Sci U S A 93(21):11327–11333

Article  CAS  PubMed  PubMed Central  Google Scholar 

Levitskaya J, Sharipo A, Leonchiks A, Ciechanover A, Masucci MG (1997) Inhibition of ubiquitin/proteasome-dependent protein degradation by the Gly-Ala repeat domain of the Epstein-Barr virus nuclear antigen 1. Proc Natl Acad Sci U S A 94(23):12616–12621

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wiertz EJ, Jones TR, Sun L, Bogyo M, Geuze HJ, Ploegh HL (1996) The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol. Cell 84(5):769–779

Article  CAS  PubMed  Google Scholar 

Früh K, Ahn K, Djaballah H, Sempé P, van Endert PM, Tampé R, Peterson PA, Yang Y (1995) A viral inhibitor of peptide transporters for antigen presentation. Nature 375(6530):415–418

Article  PubMed  Google Scholar 

Ploegh HL (1998) Viral strategies of immune evasion. Science 280(5361):248–253

Article  CAS  PubMed  Google Scholar 

Abendroth A, Morrow G, Cunningham AL, Slobedman B (2001) Varicella-Zoster virus infection of human dendritic cells and transmission to T cells: implications for virus dissemination in the host. J Virol 75(13):6183–6192

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hu H, Cohen JI (2005) Varicella-Zoster virus open reading frame 47 (ORF47) protein is critical for virus replication in dendritic cells and for spread to other cells. Virology 337(2):304–311

Article  CAS  PubMed  Google Scholar 

Morrow G, Slobedman B, Cunningham AL, Abendroth A (2003) Varicella-Zoster virus productively infects mature dendritic cells and alters their immune function. J Virol 77(8):4950–4959

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lehner PJ, Trowsdale J (1998) Antigen presentation: coming out gracefully. Curr Biol 8(17):R605–608

Article  CAS  PubMed  Google Scholar 

Coscoy L, Ganem D (2000) Kaposi’s sarcoma-associated herpesvirus encodes two proteins that block cell surface display of MHC class I chains by enhancing their endocytosis. Proc Natl Acad Sci U S A 97(14):8051–8056

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hengel H, Flohr T, Hämmerling GJ, Koszinowski UH, Momburg F (1996) Human cytomegalovirus inhibits peptide translocation into the endoplasmic reticulum for MHC class I assembly. J Gen Virol 77(Pt 9):2287–2296

Article  CAS  PubMed  Google Scholar 

Tortorella D, Gewurz BE, Furman MH, Schust DJ, Ploegh HL (2000) Viral subversion of the immune system. Annu Rev Immunol 18:861–926

Article  CAS  PubMed  Google Scholar 

Ahn K, Meyer TH, Uebel S, Sempé P, Djaballah H, Yang Y, Peterson PA, Früh K, Tampé R (1996) Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47. Embo j 15(13):3247–3255

Article  CAS  PubMed  PubMed Central  Google Scholar 

Koppers-Lalic D, Reits EA, Ressing ME, Lipinska AD, Abele R, Koch J, Marcondes Rezende M, Admiraal P, van Leeuwen D, Bienkowska-Szewczyk K et al (2005) Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing. Proc Natl Acad Sci U S A 102(14):5144–5149

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tomazin R, Hill AB, Jugovic P, York I, van Endert P, Ploegh HL, Andrews DW, Johnson DC (1996) Stable binding of the herpes simplex virus ICP47 protein to the peptide binding site of TAP. Embo j 15(13):3256–3266

Article  CAS  PubMed  PubMed Central  Google Scholar 

Eisfeld AJ, Yee MB, Erazo A, Abendroth A, Kinchington PR (2007) Downregulation of class I major histocompatibility complex surface expression by varicella-zoster virus involves open reading frame 66 protein kinase-dependent and -independent mechanisms. J Virol 81(17):9034–9049

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xing J, Wang S, Lin F, Pan W, Hu CD, Zheng C (2011) Comprehensive characterization of interaction complexes of herpes simplex virus type 1 ICP22, UL3, UL4, and UL20.5. J Virol 85(4):1881–1886

Article  CAS  PubMed  Google Scholar 

Xing J, Wang S, Lin R, Mossman KL, Zheng C (2012) Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5. J Virol 86(7):3528–3540

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhu H, Zheng C, Xing J, Wang S, Li S, Lin R, Mossman KL (2011) Varicella-Zoster virus immediate-early protein ORF61 abrogates the IRF3-mediated innate immune response through degradation of activated IRF3. J Virol 85(21):11079–11089

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang Z, Rowe J, Wang W, Sommer M, Arvin A, Moffat J, Zhu H (2007) Genetic analysis of varicella-zoster virus ORF0 to ORF4 by use of a novel luciferase bacterial artificial chromosome system. J Virol 81(17):9024–9033

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xing J, Wu F, Pan W, Zheng C (2010) Molecular anatomy of subcellular localization of HSV-1 tegument protein US11 in living cells. Virus Res 153(1):71–81

Article  CAS  PubMed  Google Scholar 

Pan W, Ren X, Guo H, Ding Q, Zheng AC (2010) Expression, purification of herpes simplex virus type 1 UL4 protein, and production and characterization of UL4 polyclonal antibody. J Virol Methods 163(2):465–469

Article  CAS  PubMed  Google Scholar 

Wang S, Wang K, Li J, Zheng C (2013) Herpes simplex virus 1 ubiquitin-specific protease UL36 inhibits beta interferon production by deubiquitinating TRAF3. J Virol 87(21):11851–11860

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu F, Xing J, Wang S, Li M, Zheng C (2011) Screening and identification of host factors interacting with UL14 of herpes simplex virus 1. Med Microbiol Immunol 200(3):203–208

Article 

留言 (0)

沒有登入
gif