Wu X, Reboll MR, Korf-Klingebiel M, Wollert KC. Angiogenesis after acute myocardial infarction. Cardiovasc Res. 2021;117(5):1257–73.

Article  CAS  PubMed  Google Scholar 

Han J, Luo L, Marcelina O, Kasim V, Wu S. Therapeutic angiogenesis-based strategy for peripheral artery disease. Theranostics. 2022;12(11):5015–33.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hadrian K, Willenborg S, Bock F, Cursiefen C, Eming SA, Hos D. Macrophage-Mediated Tissue Vascularization: Similarities and Differences Between Cornea and Skin. Front Immunol. 2021;12: 667830.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Revelo XS, Parthiban P, Chen C, Barrow F, Fredrickson G, Wang H, et al. Cardiac Resident Macrophages Prevent Fibrosis and Stimulate Angiogenesis. Circ Res. 2021;129(12):1086–101.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Capoccia BJ, Gregory AD, Link DC. Recruitment of the inflammatory subset of monocytes to sites of ischemia induces angiogenesis in a monocyte chemoattractant protein-1-dependent fashion. J Leukoc Biol. 2008;84(3):760–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cochain C, Rodero MP, Vilar J, Recalde A, Richart AL, Loinard C, et al. Regulation of monocyte subset systemic levels by distinct chemokine receptors controls post-ischaemic neovascularization. Cardiovasc Res. 2010;88(1):186–95.

Article  CAS  PubMed  Google Scholar 

Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, Figueiredo JL, et al. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med. 2007;204(12):3037–47.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wynn TA, Chawla A, Pollard JW. Macrophage biology in development, homeostasis and disease. Nature. 2013;496(7446):445–55.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Murray PJ. Macrophage Polarization. Annu Rev Physiol. 2017;79:541–66.

Article  CAS  PubMed  Google Scholar 

Wang N, Liang H, Zen K. Molecular mechanisms that influence the macrophage m1–m2 polarization balance. Front Immunol. 2014;5:614.

Article  PubMed  PubMed Central  Google Scholar 

Mantovani A, Biswas SK, Galdiero MR, Sica A, Locati M. Macrophage plasticity and polarization in tissue repair and remodelling. J Pathol. 2013;229(2):176–85.

Article  CAS  PubMed  Google Scholar 

Zhu D, Johnson TK, Wang Y, Thomas M, Huynh K, Yang Q, et al. Macrophage M2 polarization induced by exosomes from adipose-derived stem cells contributes to the exosomal proangiogenic effect on mouse ischemic hindlimb. Stem Cell Res Ther. 2020;11(1):162.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vagnozzi RJ, Maillet M, Sargent MA, Khalil H, Johansen AKZ, Schwanekamp JA, et al. An acute immune response underlies the benefit of cardiac stem cell therapy. Nature. 2020;577(7790):405–9.

Article  CAS  PubMed  Google Scholar 

Takizawa H, Manz MG. Macrophage tolerance: CD47-SIRP-alpha-mediated signals matter. Nat Immunol. 2007;8(12):1287–9.

Article  CAS  PubMed  Google Scholar 

Zhu D, Pan C, Li L, Bian Z, Lv Z, Shi L, et al. MicroRNA-17/20a/106a modulate macrophage inflammatory responses through targeting signal-regulatory protein alpha. J Allergy Clin Immunol. 2013;132(2):426–36 e8.

Matozaki T, Murata Y, Okazawa H, Ohnishi H. Functions and molecular mechanisms of the CD47-SIRPalpha signalling pathway. Trends Cell Biol. 2009;19(2):72–80.

Article  CAS  PubMed  Google Scholar 

Barclay AN, Van den Berg TK. The interaction between signal regulatory protein alpha (SIRPalpha) and CD47: structure, function, and therapeutic target. Annu Rev Immunol. 2014;32:25–50.

Article  CAS  PubMed  Google Scholar 

Russ A, Hua AB, Montfort WR, Rahman B, Riaz IB, Khalid MU, et al. Blocking “don’t eat me” signal of CD47-SIRPalpha in hematological malignancies, an in-depth review. Blood Rev. 2018;32(6):480–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bauer PM, Bauer EM, Rogers NM, Yao M, Feijoo-Cuaresma M, Pilewski JM, et al. Activated CD47 promotes pulmonary arterial hypertension through targeting caveolin-1. Cardiovasc Res. 2012;93(4):682–93.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Veillette A, Chen J. SIRPalpha-CD47 Immune Checkpoint Blockade in Anticancer Therapy. Trends Immunol. 2018;39(3):173–84.

Article  CAS  PubMed  Google Scholar 

McCracken MN, Cha AC, Weissman IL. Molecular Pathways: Activating T Cells after Cancer Cell Phagocytosis from Blockade of CD47 “Don’t Eat Me” Signals. Clin Cancer Res. 2015;21(16):3597–601.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Craig WA. Does the dose matter? Clin Infect Dis. 2001;33(Suppl 3):S233–7.

Article  CAS  PubMed  Google Scholar 

Entman ML, Michael L, Rossen RD, Dreyer WJ, Anderson DC, Taylor AA, et al. Inflammation in the course of early myocardial ischemia. FASEB J. 1991;5(11):2529–37.

Article  CAS  PubMed  Google Scholar 

Neri Serneri GG, Boddi M, Modesti PA, Cecioni I, Coppo M, Papa ML, et al. Immunomediated and ischemia-independent inflammation of coronary microvessels in unstable angina. Circ Res. 2003;92(12):1359–66.

Article  CAS  PubMed  Google Scholar 

Jetten N, Verbruggen S, Gijbels MJ, Post MJ, De Winther MP, Donners MM. Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo. Angiogenesis. 2014;17(1):109–18.

Article  CAS  PubMed  Google Scholar 

Shibuya M. Vascular Endothelial Growth Factor (VEGF) and Its Receptor (VEGFR) Signaling in Angiogenesis: A Crucial Target for Anti- and Pro-Angiogenic Therapies. Genes Cancer. 2011;2(12):1097–105.

Article  PubMed  PubMed Central  Google Scholar 

Martinez FO. Regulators of macrophage activation. Eur J Immunol. 2011;41(6):1531–4.

Article  CAS  PubMed  Google Scholar 

van Beek EM, Cochrane F, Barclay AN, van den Berg TK. Signal regulatory proteins in the immune system. J Immunol. 2005;175(12):7781–7.

Article  PubMed  Google Scholar 

Xia T, Zhang M, Lei W, Yang R, Fu S, Fan Z, et al. Advances in the role of STAT3 in macrophage polarization. Front Immunol. 2023;14:1160719.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Czimmerer Z, Daniel B, Horvath A, Ruckerl D, Nagy G, Kiss M, et al. The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages. Immunity. 2018;48(1):75–90 e6.

Zhang H, Lu H, Xiang L, Bullen JW, Zhang C, Samanta D, et al. HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells. Proc Natl Acad Sci U S A. 2015;112(45):E6215–23.

Article  CAS  PubMed  PubMed Central