Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, MacDonald K, Speert D, Fernandes-Alnemri T, Wu J, Monks BG, Fitzgerald KA, Hornung V, Latz E (2009) Cutting Edge: NF-κB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 Expression1. J Immunol 183:787–791. https://doi.org/10.4049/jimmunol.0901363
Article CAS PubMed Google Scholar
Berkel C, Cacan E (2021) Differential expression and Copy Number Variation of Gasdermin (GSDM) Family Members, Pore-forming proteins in Pyroptosis. Normal Malignant Serous Ovarian Tissue Inflamm 44:2203–2216. https://doi.org/10.1007/s10753-021-01493-0
Braga LdaC, Silva LM, Ramos APÁ da, Piedade S, Vidigal JB, Traiman PVT, Silva Filho P, da AL (2014) Single CpG island methylation is not sufficient to maintain the silenced expression of CASPASE-8 apoptosis-related gene among women with epithelial ovarian cancer. Biomedicine & Pharmacotherapy 68, 87–91. https://doi.org/10.1016/j.biopha.2013.12.004
Browning L, Patel MR, Horvath EB, Tawara K, Jorcyk CL (2018) IL-6 and ovarian cancer: inflammatory cytokines in promotion of metastasis. Cancer Manag Res 10:6685–6693. https://doi.org/10.2147/CMAR.S179189
Article CAS PubMed PubMed Central Google Scholar
Broz P, Pelegrín P, Shao F (2020) The gasdermins, a protein family executing cell death and inflammation. Nat Rev Immunol 20:143–157. https://doi.org/10.1038/s41577-019-0228-2
Article CAS PubMed Google Scholar
Cai DL, Jin L-P (2017) Immune Cell Population in Ovarian Tumor Microenvironment. J Cancer 8:2915–2923. https://doi.org/10.7150/jca.20314
Article CAS PubMed PubMed Central Google Scholar
Canakinumab’s cancer career ends with a whimper [WWW Document] (2022) Evaluate.com. URL https://www.evaluate.com/vantage/articles/news/trial-results/canakinumabs-cancer-career-ends-whimper (accessed 9.7.23)
Cancer Research UK (2021) Epithelial ovarian cancer [WWW Document]. Epithelial Ovarian Cancer. URL https://about-cancer.cancerresearchuk.org/about-cancer/ovarian-cancer/types/epithelial-ovarian-cancers/epithelial (accessed 2.14.24).
Cantargia advances TRIFOUR trial to randomized stage following promising early safety and efficacy of nadunolimab in triple-negative breast cancer - Cantargia [WWW Document], n.d. URL https://cantargia.com/en/press-releases/cantargia-advances-trifour-trial-to-randomized-stage-following-promising-early-safety-and-efficacy-of-nadunolimab-in-triple-negative-breast-cancer (accessed 9.7.23)
Cao X, Zhang Q, Zhu Y, Huo X, Bao J, Su M (2022) Derivation, Comprehensive Analysis, and assay validation of a pyroptosis-related lncRNA prognostic signature in patients with ovarian Cancer. Front Oncol 12:780950. https://doi.org/10.3389/fonc.2022.780950
Article CAS PubMed PubMed Central Google Scholar
Chang C-M, Wang M-L, Lu K-H, Yang Y-P, Juang C-M, Wang P-H, Hsu R-J, Yu M-H, Chang C-C (2017) Integrating the dysregulated inflammasome-based molecular functionome in the malignant transformation of endometriosis-associated ovarian carcinoma. Oncotarget 9:3704–3726. https://doi.org/10.18632/oncotarget.23364
Article PubMed PubMed Central Google Scholar
Chen L, Huang C-F, Li Y-C, Deng W-W, Mao L, Wu L, Zhang W-F, Zhang L, Sun Z-J (2018) Blockage of the NLRP3 inflammasome by MCC950 improves anti-tumor immune responses in head and neck squamous cell carcinoma. Cell Mol Life Sci 75:2045–2058. https://doi.org/10.1007/s00018-017-2720-9
Article CAS PubMed Google Scholar
Colvin EK (2014) Tumor-Associated macrophages Contribute to Tumor Progression in Ovarian Cancer. Front Oncol 4:137. https://doi.org/10.3389/fonc.2014.00137
Article PubMed PubMed Central Google Scholar
Conte A, Paladino S, Bianco G, Fasano D, Gerlini R, Tornincasa M, Renna M, Fusco A, Tramontano D, Pierantoni GM (2017) High mobility group A1 protein modulates autophagy in cancer cells. Cell Death Differ 24:1948–1962. https://doi.org/10.1038/cdd.2017.117
Article CAS PubMed PubMed Central Google Scholar
Dupaul-Chicoine J, Arabzadeh A, Dagenais M, Douglas T, Champagne C, Morizot A, Rodrigue-Gervais IG, Breton V, Colpitts SL, Beauchemin N, Saleh M (2015) The Nlrp3 Inflammasome suppresses Colorectal Cancer Metastatic Growth in the liver by promoting natural killer cell tumoricidal activity. Immunity 43:751–763. https://doi.org/10.1016/j.immuni.2015.08.013
Article CAS PubMed Google Scholar
Ershaid N, Sharon Y, Doron H, Raz Y, Shani O, Cohen N, Monteran L, Leider-Trejo L, Ben-Shmuel A, Yassin M, Gerlic M, Ben-Baruch A, Pasmanik-Chor M, Apte R, Erez N (2019) NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis. Nat Commun 10:4375. https://doi.org/10.1038/s41467-019-12370-8
Article CAS PubMed PubMed Central Google Scholar
Hanahan D, Weinberg RA (2011) Hallmarks of Cancer: the Next Generation. Cell 144:646–674. https://doi.org/10.1016/j.cell.2011.02.013
Article CAS PubMed Google Scholar
Heath O, Berlato C, Maniati E, Lakhani A, Pegrum C, Kotantaki P, Elorbany S, Böhm S, Barry ST, Annibaldi A, Barton DP, Balkwill FR (2021) Chemotherapy induces Tumor-Associated macrophages that Aid Adaptive Immune responses in Ovarian Cancer. Cancer Immunol Res 9:665–681. https://doi.org/10.1158/2326-6066.CIR-20-0968
Article CAS PubMed PubMed Central Google Scholar
Hernandez C, Huebener P, Schwabe RF (2016) Damage-associated molecular patterns in cancer: a double-edged sword. Oncogene 35:5931–5941. https://doi.org/10.1038/onc.2016.104
Article CAS PubMed PubMed Central Google Scholar
He W, Wan H, Hu L, Chen P, Wang X, Huang Z, Yang Z-H, Zhong C-Q, Han J (2015) Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion. Cell Res 25:1285–1298. https://doi.org/10.1038/cr.2015.139
Article CAS PubMed PubMed Central Google Scholar
Hsu P-C, Chao T-K, Chou Y-C, Yu M-H, Wang Y-C, Lin Y-H, Lee Y-L, Liu L-C, Chang C-C (2021) AIM2 Inflammasome in Tumor cells as a Biomarker for Predicting the treatment response to antiangiogenic therapy in epithelial ovarian Cancer patients. J Clin Med 10:4529. https://doi.org/10.3390/jcm10194529
Article CAS PubMed PubMed Central Google Scholar
Huai W, Zhao R, Song H, Zhao J, Zhang L, Zhang L, Gao C, Han L, Zhao W (2014) Aryl hydrocarbon receptor negatively regulates NLRP3 inflammasome activity by inhibiting NLRP3 transcription. Nat Commun 5:4738. https://doi.org/10.1038/ncomms5738
Article CAS PubMed Google Scholar
Huang W, Wu Y, Luo N, Shuai X, Guo J, Wang C, Yang F, Liu L, Liu S, Cheng Z (2023) Identification of TRPM2 as a prognostic factor correlated with immune infiltration in ovarian cancer. J Ovarian Res 16:169. https://doi.org/10.1186/s13048-023-01225-y
Article CAS PubMed PubMed Central Google Scholar
Huang Y, Jiang H, Chen Y, Wang X, Yang Y, Tao J, Deng X, Liang G, Zhang H, Jiang W, Zhou R (2018) Tranilast directly targets NLRP3 to treat inflammasome-driven diseases. EMBO Mol Med 10:e8689. https://doi.org/10.15252/emmm.201708689
Article CAS PubMed PubMed Central Google Scholar
Isambert N, Hervieu A, Rébé C, Hennequin A, Borg C, Zanetta S, Chevriaux A, Richard C, Derangère V, Limagne E, Blanc J, Bertaut A, Ghiringhelli F (2018) Fluorouracil and bevacizumab plus anakinra for patients with metastatic colorectal cancer refractory to standard therapies (IRAFU): a single-arm phase 2 study. Oncoimmunology 7:e1474319. https://doi.org/10.1080/2162402X.2018.1474319
Article PubMed PubMed Central Google Scholar
Juliana C, Fernandes-Alnemri T, Kang S, Farias A, Qin F, Alnemri ES (2012) Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation. J Biol Chem 287:36617–36622. https://doi.org/10.1074/jbc.M112.407130
Article CAS PubMed PubMed Central Google Scholar
Ju M, Bi J, Wei Q, Jiang L, Guan Q, Zhang M, Song X, Chen T, Fan J, Li X, Wei M, Zhao L (2020) Pan-cancer analysis of NLRP3 inflammasome with potential implications in prognosis and immunotherapy in human cancer. Brief Bioinform 22:bbaa345. https://doi.org/10.1093/bib/bbaa345
Article CAS PubMed Central Google Scholar
Keita M, Bessette P, Pelmus M, Ainmelk Y, Aris A (2010) Expression of interleukin-1 (IL-1) ligands system in the most common endometriosis-associated ovarian cancer subtypes. J Ovarian Res 3:3. https://doi.org/10.1186/1757-2215-3-3
留言 (0)