Exploring miRNA therapies and gut microbiome–enhanced CAR-T cells: advancing frontiers in glioblastoma stem cell targeting

Agnihotri TG, Salave S, Shinde T, Srikanth I, Gyanani V, Haley JC, Jain A (2023) Understanding the role of endothelial cells in brain tumor formation and metastasis: a proposition to be explored for better therapy. J National Cancer Cent. https://doi.org/10.1016/j.jncc.2023.08.001

Article  Google Scholar 

Agosti E, Garaba A, Antonietti S, Ius T, Fontanella MM, Zeppieri M, Panciani PP (2024) CAR-T cells therapy in glioblastoma: a systematic review on molecular targets and treatment strategies. Int J Mol Sci 25(13):7174. https://doi.org/10.3390/ijms25137174

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ahmed SP, Castresana JS, Shahi MH (2021) Glioblastoma and MiRNAs. Cancers 13(7):1581. https://doi.org/10.3390/cancers13071581

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ali S, Ahmad A, Aboukameel A, Ahmed A, Bao B, Banerjee S, Philip PA, Sarkar FH (2014) Deregulation of miR-146a expression in a mouse model of pancreatic cancer affecting EGFR signaling. Cancer Lett 351(1):134–142. https://doi.org/10.1016/j.canlet.2014.05.013

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ali YF, Cucinotta FA, Ning-Ang L, Zhou G (2020) Cancer risk of low dose ionizing radiation. Front Phys 8:532248. https://doi.org/10.3389/FPHY.2020.00234/BIBTEX

Article  Google Scholar 

Aloizou A-M, Pateraki G, Siokas V, Mentis A-FA, Liampas I, Lazopoulos G, Kovatsi L, Mitsias PD, Bogdanos DP, Paterakis K, Dardiotis E (2020) The role of MiRNA-21 in gliomas: hope for a novel therapeutic intervention? Toxicol Rep 7:1514–1530. https://doi.org/10.1016/j.toxrep.2020.11.001

Article  CAS  PubMed  PubMed Central  Google Scholar 

An Z, Hu Y, Bai Y, Zhang C, Xu C, Kang X, Yang S, Li W, Zhong X (2021) Antitumor activity of the third generation EphA2 CAR-T cells against glioblastoma is associated with interferon gamma induced PD-L1. OncoImmunology 10(1):1960728. https://doi.org/10.1080/2162402X.2021.1960728

Article  PubMed  PubMed Central  Google Scholar 

Andersen JK, Miletic H, Hossain JA (2022) Tumor-associated macrophages in gliomas-basic insights and treatment opportunities. Cancers 14(5):1319. https://doi.org/10.3390/cancers14051319

Article  CAS  PubMed  PubMed Central  Google Scholar 

Araji G, Maamari J, Ahmad FA, Zareef R, Chaftari P, Yeung S-CJ (2022) The emerging role of the gut microbiome in the cancer response to immune checkpoint inhibitors: a narrative review. J Immunother Precis Oncol 5(1):13–25. https://doi.org/10.36401/JIPO-21-10

Article  PubMed  Google Scholar 

Asokan S, Cullin N, Stein-Thoeringer CK, Elinav E (2023) CAR-T cell therapy and the gut microbiota. Cancers 15(3):794. https://doi.org/10.3390/cancers15030794

Article  CAS  PubMed  PubMed Central  Google Scholar 

Augenlicht A, Saiselet M, Decaussin-Petrucci M, Andry G, Dumont JE, Maenhaut C (2021) MiR-7–5p inhibits thyroid cell proliferation by targeting the EGFR/MAPK and IRS2/PI3K signaling pathways. Oncotarget 12(16):1587–1599. https://doi.org/10.18632/oncotarget.28030

Article  PubMed  PubMed Central  Google Scholar 

Aziz F, Chakraborty A, Khan I, Monts J (2022) Relevance of miR-223 as potential diagnostic and prognostic markers in cancer. Biol 11(2):249. https://doi.org/10.3390/biology11020249

Article  CAS  Google Scholar 

Bagley SJ, Kothari S, Rahman R, Lee EQ, Dunn GP, Galanis E, Chang SM, Nabors LB, Ahluwalia MS, Stupp R, Mehta MP, Reardon DA, Grossman SA, Sulman EP, Sampson JH, Khagi S, Weller M, Cloughesy TF, Wen PY, Khasraw M (2022) Glioblastoma clinical trials: current landscape and opportunities for improvement. Clin Cancer Res 28(4):594–602. https://doi.org/10.1158/1078-0432.CCR-21-2750

Article  PubMed  PubMed Central  Google Scholar 

Bausart M, Préat V, Malfanti A (2022) Immunotherapy for glioblastoma: the promise of combination strategies. J Exp Clin Cancer Res 41(1):35. https://doi.org/10.1186/S13046-022-02251-2

Article  CAS  PubMed  PubMed Central  Google Scholar 

Beylerli O, Gareev I, Sufianov A, Ilyasova T, Zhang F (2022) The role of microRNA in the pathogenesis of glial brain tumors. Non-Coding RNA Res 7(2):71–76. https://doi.org/10.1016/j.ncrna.2022.02.005

Article  CAS  Google Scholar 

Bhattacharjee B, Syeda AF, Rynjah D, Hussain SM, Chandra Bora S, Pegu P, Sahu RK, Khan J (2023) Pharmacological impact of microRNAs in head and neck squamous cell carcinoma: prevailing insights on molecular pathways, diagnosis, and nanomedicine treatment. Front Pharmacol 14:1174330. https://doi.org/10.3389/fphar.2023.1174330

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bie L, Li N, Deng W, Lu X, Guo P, Luo S (2020) <p>Serum miR-191 and miR-425 as diagnostic and prognostic markers of advanced gastric cancer can predict the sensitivity of FOLFOX chemotherapy regimen</p>. Onco Targets Ther 13:1705–1715. https://doi.org/10.2147/OTT.S233086

Article  CAS  PubMed  PubMed Central  Google Scholar 

Blecharz-Lang KG, Wagner J, Fries A, Nieminen-Kelhä M, Rösner J, Schneider UC, Vajkoczy P (2018) Interleukin 6-mediated endothelial barrier disturbances can be attenuated by blockade of the IL6 receptor expressed in brain microvascular endothelial cells. Transl Stroke Res 9(6):631–642. https://doi.org/10.1007/s12975-018-0614-2

Article  CAS  PubMed  Google Scholar 

Bouzari B, Mohammadi S, Bokov DO, Krasnyuk II, Hosseini-Fard SR, Hajibaba M, Mirzaei R, Karampoor S (2022) Angioregulatory role of miRNAs and exosomal miRNAs in glioblastoma pathogenesis. Biomed Pharmacother 148:112760. https://doi.org/10.1016/j.biopha.2022.112760

Article  CAS  PubMed  Google Scholar 

Boyd NH, Tran AN, Bernstock JD, Etminan T, Jones AB, Gillespie GY, Friedman GK, Hjelmeland AB (2021) Glioma stem cells and their roles within the hypoxic tumor microenvironment. Theranostics 11(2):665–683. https://doi.org/10.7150/thno.41692

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bu S, Lau SSY, Yong WL, Zhang H, Thiagarajan S, Bashirullah A, Yu F (2023) Polycomb group genes are required for neuronal pruning in Drosophila. BMC Biol 21(1):33. https://doi.org/10.1186/s12915-023-01534-0

Article  CAS  PubMed  PubMed Central  Google Scholar 

Budi HS, Younus LA, Lafta MH, Parveen S, Mohammad HJ, Al-Qaim ZH, Jawad MA, Parra RMR, Mustafa YF, Alhachami FR, Karampoor S, Mirzaei R (2022) The role of miR-128 in cancer development, prevention, drug resistance, and immunotherapy. Front Oncol 12:1067974. https://doi.org/10.3389/fonc.2022.1067974

Article  CAS  PubMed  Google Scholar 

Cao D, Di M, Liang J, Shi S, Tan Q, Wang Z (2020) MicroRNA-183 in cancer progression. J Cancer 11(6):1315–1324. https://doi.org/10.7150/jca.39044

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cardoso AM, Morais CM, Pena F, Marante T, Cunha PP, Jurado AS, Pedroso de Lima MC (2021) Differentiation of glioblastoma stem cells promoted by miR-128 or miR-302a overexpression enhances senescence-associated cytotoxicity of axitinib. Hum Mol Genet 30(3–4):160–171. https://doi.org/10.1093/hmg/ddab011

Article  CAS  PubMed  Google Scholar 

Cenciarini M, Valentino M, Belia S, Sforna L, Rosa P, Ronchetti S, D’Adamo MC, Pessia M (2019) Dexamethasone in glioblastoma multiforme therapy: mechanisms and controversies. Front Mol Neurosci 12:448734. https://doi.org/10.3389/FNMOL.2019.00065/BIBTEX

Article  Google Scholar 

Chavda VP, Sugandhi VV, Pardeshi CV, Patil RJ, Joshi M, Patel B, Khadela A, Bezbaruah R, Bhattacharjee B, Balar PC, Vora LK (2023) Engineered exosomes for cancer theranostics: next-generation tumor targeting. J Drug Deliv Sci Technol 85:104579. https://doi.org/10.1016/j.jddst.2023.104579

Article  CAS  Google Scholar 

Chen J-Q, Huang Z-P, Li H-F, Ou Y-L, Huo F, Hu L-K (2020) MicroRNA-520f-3p inhibits proliferation of gastric cancer cells via targeting SOX9 and thereby inactivating Wnt signaling. Sci Rep 10(1):6197. https://doi.org/10.1038/s41598-020-63279-y

Article 

留言 (0)

沒有登入
gif