The healing effect of nano emulsified Plantago major L extract on oral wounds in a wistar rat model

Greenberg MS. Ulcerative, vesicular, and bullous lesions. Burket’s Oral Medicine Diagnosis & Treatment 2003.

Pannerselvam B, Jothinathan MKD, Rajenderan M, Perumal P, Thangavelu KP, Kim HJ, Singh V, Rangarajulu SK. An in vitro study on the burn wound healing activity of cotton fabrics incorporated with phytosynthesized silver nanoparticles in male Wistar albino rats. Eur J Pharm Sci. 2017;100:187–96.

Article  PubMed  Google Scholar 

Bouchemal K, Briançon S, Perrier E, Fessi H. Nano-emulsion formulation using spontaneous emulsification: solvent, oil and surfactant optimisation. Int J Pharm. 2004;280(1–2):241–51.

Article  PubMed  Google Scholar 

Yang Y, Wang F, Yin D, Fang Z, Huang L. Astragulus polysaccharide-loaded fibrous mats promote the restoration of microcirculation in/around skin wounds to accelerate wound healing in a diabetic rat model. Colloids Surf B. 2015;136:111–8.

Article  Google Scholar 

Ranjbar-Mohammadi M, Rabbani S, Bahrami SH, Joghataei M, Moayer F. Antibacterial performance and in vivo diabetic wound healing of curcumin loaded gum tragacanth/poly (ε-caprolactone) electrospun nanofibers. Mater Sci Engineering: C. 2016;69:1183–91.

Article  Google Scholar 

Vargas ET, do, Vale Baracho N, De Brito J, De Queiroz A. Hyperbranched polyglycerol electrospun nanofibers for wound dressing applications. Acta biomaterialia 2010, 6(3):1069–1078.

Vélez I, Tamara LA, Mintz S. Management of oral mucositis induced by chemotherapy and radiotherapy: an update. Quintessence Int. 2004;35(2):129–36.

PubMed  Google Scholar 

Noudeh GD, Sharififar F, Noodeh rD, Sakhtianch R. Antitumor and antibacterial activity of four fractions from Heracleum Persicum Desf. And Cinnamomum zeylanicum Blume. J Med Plants Res. 2010;4:2176–80.

Google Scholar 

Sharififar F, Mirtajadini M, Azampour MJ, Zamani E. Essential oil and methanolic extract of Zataria multiflora Boiss with anticholinesterase effect. Pak J Biol Sci. 2012;15(1):49–53.

Article  PubMed  Google Scholar 

Son MJ, Kim YE, Song YI, Kim YH. Herbal medicines for treating acute otitis media: a systematic review of randomised controlled trials. Complement Ther Med. 2017;35:133–9.

Article  PubMed  Google Scholar 

Khan MA, Kassianos AJ, Hoy WE, Alam AK, Healy HG, Gobe GC. Promoting plant-based therapies for chronic kidney disease. J Evid Based Integr Med. 2022;27:2515690X221079688.

Article  PubMed  PubMed Central  Google Scholar 

Prayoga DK, Aulifa DL, Budiman A, Levita J. Plants with anti-ulcer activity and mechanism: a review of preclinical and clinical studies. Drug Des Devel Ther. 2024;18:193–213.

Article  PubMed  PubMed Central  Google Scholar 

Hamedi S, Sadeghpour O, Shamsardekani MR, Amin G, Hajighasemali D, Feyzabadi Z. The most common herbs to cure the most common oral disease: Stomatitis Recurrent Aphthous Ulcer (RAU). Iran Red Crescent Med J. 2016;18(2):e21694.

Article  PubMed  PubMed Central  Google Scholar 

Eubank PLC, Abreu LG, Violante IP, Volpato LER. Medicinal plants used for the treatment of mucositis induced by oncotherapy: a systematic review. Support Care Cancer. 2021;29(11):6981–93.

Article  PubMed  Google Scholar 

Srivastava A, Gc S, Pathak S, Ingle E, Kumari A, Shivakumar S, Pg NK, Singh AK. Evidence-based effectiveness of herbal treatment modality for recurrent aphthous ulcers - a systematic review and meta-analysis. Natl J Maxillofac Surg. 2021;12(3):303–10.

Article  PubMed  PubMed Central  Google Scholar 

Li CL, Huang HL, Wang WC, Hua H. Efficacy and safety of topical herbal medicine treatment on recurrent aphthous stomatitis: a systemic review. Drug Des Devel Ther. 2016;10:107–15.

PubMed  Google Scholar 

Rameshk M, Sharififar F, Mehrabani M, Pardakhty A, Farsinejad A, Mehrabani M. Proliferation and in Vitro Wound Healing effects of the microniosomes containing Narcissus tazetta L. Bulb extract on primary human fibroblasts (HDFs). Daru. 2018;26(1):31–42.

Article  PubMed  PubMed Central  Google Scholar 

Raeiszadeh M, Pardakhty A, Sharififar F, Mehrabani M, Nejat-Mehrab-Kermani H, Mehrabani M. Phytoniosome: a Novel Drug Delivery for Myrtle Extract. Iran J Pharm Res. 2018;17(3):804–17.

PubMed  PubMed Central  Google Scholar 

Puglia C, Lauro MR, Tirendi GG, Fassari GE, Carbone C, Bonina F, Puglisi G. Modern drug delivery strategies applied to natural active compounds. Expert Opin Drug Deliv. 2017;14(6):755–68.

Article  PubMed  Google Scholar 

Anton N, Vandamme TF. Nano-emulsions and micro-emulsions: clarifications of the critical differences. Pharm Res. 2011;28(5):978–85.

Article  PubMed  Google Scholar 

Koroleva MY, Yurtov EV. Nanoemulsions: the properties, methods of preparation and promising applications. Rus Chem Rev. 2012;81(1):21.

Article  Google Scholar 

Hajialyani M, Tewari D, Sobarzo-Sánchez E, Nabavi SM, Farzaei MH, Abdollahi M. Natural product-based nanomedicines for wound healing purposes: therapeutic targets and drug delivery systems. Int J Nanomed 2018:5023–43.

Fidoski J, Benedetti A, Kirkov A, Iliev A, Stamatoski A, Baftijari D. Nano-Emulsion complex (propolis and vitamin C) promotes wound healing in the oral mucosa. Oral Maxillofacial Pathol J 2020, 11(1).

Farid A, Sheibani M, Shojaii A, Noori M, Motevalian M. Evaluation of anti-inflammatory effects of leaf and seed extracts of Plantago major on acetic acid-induced ulcerative colitis in rats. J Ethnopharmacol. 2022;298:115595.

Article  PubMed  Google Scholar 

Samuelsen AB. The traditional uses, chemical constituents and biological activities of Plantago major L. A review. J Ethnopharmacol. 2000;71(1–2):1–21.

Article  PubMed  PubMed Central  Google Scholar 

Ghanadian M, Soltani R, Homayouni A, Khorvash F, Jouabadi SM, Abdollahzadeh M. The effect of Plantago major hydroalcoholic extract on the healing of diabetic foot and pressure ulcers: a randomized open-label controlled clinical trial. Int J Low Extrem Wounds 2022:15347346211070723.

Najafian Y, Hamedi SS, Farshchi MK, Feyzabadi Z. Plantago major in traditional Persian Medicine and modern phytotherapy: a narrative review. Electron Physician. 2018;10(2):6390–9.

Article  PubMed  PubMed Central  Google Scholar 

Baldea I, Lung I, Opris O, Stegarescu A, Kacso I, Soran ML. Antioxidant, anti-inflammatory effects and ability to stimulate Wound Healing of a common-plantain extract in Alginate Gel formulations. Gels 2023, 9(11).

Kartini K, Wati N, Gustav R, Wahyuni R, Anggada YF, Hidayani R, Raharjo A, Islamie R, Putra SED. Wound healing effects of Plantago major extract and its chemical compounds in hyperglycemic rats. Food Bioscience. 2021;41:100937.

Article  Google Scholar 

Ashkani-Esfahani S, Khoshneviszadeh M, Noorafshan A, Miri R, Rafiee S, Hemyari K, Kardeh S, Hosseinabadi OK, Fani D, Faridi E. The healing effect of Plantago major and Aloe vera mixture in excisional full thickness skin wounds: stereological study. World J Plast Surg. 2019;8(1):51.

Article  PubMed  PubMed Central  Google Scholar 

Logarto Parra A, Silva Yhebra R, Guerra Sardinas I, Iglesias Buela L. Comparative study of the assay of Artemia salina L. and the estimate of the medium lethal dose (LD50 value) in mice, to determine oral acute toxicity of plant extracts. Phytomedicine. 2001;8(5):395–400.

Article  PubMed  Google Scholar 

Masson-Meyers DS, Andrade TAM, Caetano GF, Guimaraes FR, Leite MN, Leite SN, Frade MAC. Experimental models and methods for cutaneous wound healing assessment. Int J Exp Pathol. 2020;101(1–2):21–37.

Article  PubMed  PubMed Central  Google Scholar 

Sarhadynejad Z, Sharififar F, Pardakhty A, Nematollahi MH, Sattaie-Mokhtari S, Mandegary A. Pharmacological safety evaluation of a traditional herbal medicine Zereshk-e-Saghir and assessment of its hepatoprotective effects on carbon tetrachloride induced hepatic damage in rats. J Ethnopharmacol. 2016;190:387–95.

Article  PubMed  Google Scholar 

Zahabi ZF, Sharififar F, Almani PGN, Salari S. Antifungal activities of different fractions of Salvia Rhytidea Benth as a valuable medicinal plant against different Candida species in Kerman province (Southeast of Iran). Gene Rep 2020, 19.

Khazaeli P, Goldoozian R, Sharififar F. An evaluation of extracts of five traditional medicinal plants from Iran on the inhibition of mushroom tyrosinase activity and scavenging of free radicals. Int J Cosmet Sci. 2009;31(5):375–81.

Article  PubMed  Google Scholar 

Green C, Knight J, Precious S, Simpkin S. Ketamine alone and combined with diazepam or xylazine in laboratory animals: a 10 year experience. Lab Anim. 1981;15(2):163–70.

Article  PubMed  Google Scholar 

Rosenstein ED, Kushner LJ, Kramer N, Kazandjian G. Pilot study of dietary fatty acid supplementation in the treatment of adult periodontitis. Prostaglandins Leukot Essent Fatty Acids. 2003;68(3):213–8.

Article  PubMed  Google Scholar 

Amini M, Kherad M, Mehrabani D, Azarpira N, Panjehshahin M, Tanideh N. Effect of Plantago major on burn wound healing in rat. J Appl Anim Res. 2010;37(1):53–6.

Article  Google Scholar 

Pant P, Pandey S, Dall’Acqua S. The influence of environmental conditions on secondary metabolites in Medicinal plants: a Literature Review. Chem Biodivers. 2021;18(11):e2100345.

Article  PubMed  Google Scholar 

Vitale S, Colanero S, Placidi M, Di Emidio G, Tatone C, Amicarelli F, D’Alessandro AM. Phytochemistry and Biological Activity of Medicinal plants in Wound Healing: an overview of current research. Molecules 2022, 27(11).

Scialo F, Fernandez-Ayala DJ, Sanz A. Role of Mitochondrial Reverse Electron Transport in ROS Signaling: potential roles in Health and Disease. Front Physiol. 2017;8:428.

Article  PubMed 

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