Celli BR, Wedzicha JA. Update on Clinical Aspects of Chronic Obstructive Pulmonary Disease. N Engl J Med. 2019;381(13):1257–66.

Article  PubMed  Google Scholar 

Adherence to Global Initiative for Chronic Obstructive Lung Disease guidelines in the real world: current understanding, barriers, and solutions. Current Opinion in Pulmonary Medicine 2020, 26.

Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006;3(11):e442.

Article  PubMed  PubMed Central  Google Scholar 

Adeloye D, Chua S, Lee C, Basquill C, Papana A, Theodoratou E, Nair H, Gasevic D, Sridhar D, Campbell H, et al. Global and regional estimates of COPD prevalence: Systematic review and meta-analysis. J Glob Health. 2015;5(2):020415.

Article  PubMed  PubMed Central  Google Scholar 

Stolz D, Mkorombindo T, Schumann DM, Agusti A, Ash SY, Bafadhel M, Bai C, Chalmers JD, Criner GJ, Dharmage SC, et al. Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission. Lancet. 2022;400(10356):921–72.

Article  PubMed  PubMed Central  Google Scholar 

Zhou M, Wang H, Zeng X, Yin P, Zhu J, Chen W, Li X, Wang L, Wang L, Liu Y, et al. Mortality, morbidity, and risk factors in China and its provinces, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2019;394(10204):1145–58.

Article  PubMed  PubMed Central  Google Scholar 

Liang W, Yang Y, Gong S, Wei M, Ma Y, Feng R, Gao J, Liu X, Tu F, Ma W, et al. Airway dysbiosis accelerates lung function decline in chronic obstructive pulmonary disease. Cell Host Microbe. 2023;31(6):1054-1070.e1059.

Article  PubMed  Google Scholar 

Dransfield MT, Kunisaki KM, Strand MJ, Anzueto A, Bhatt SP, Bowler RP, Criner GJ, Curtis JL, Hanania NA, Nath H, et al. Acute Exacerbations and Lung Function Loss in Smokers with and without Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2017;195(3):324–30.

Article  PubMed  PubMed Central  Google Scholar 

Halpin DMG, Criner GJ, Papi A, Singh D, Anzueto A, Martinez FJ, Agusti AA, Vogelmeier CF: Global Initiative for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease. The 2020 GOLD Science Committee Report on COVID-19 and Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med 2021, 203(1):24–36.

Watz H, Tetzlaff K, Wouters EF, Kirsten A, Magnussen H, Rodriguez-Roisin R, Vogelmeier C, Fabbri LM, Chanez P, Dahl R, et al. Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the WISDOM trial. Lancet Respir Med. 2016;4(5):390–8.

Article  PubMed  Google Scholar 

Calverley PMA, Tetzlaff K, Vogelmeier C, Fabbri LM, Magnussen H, Wouters EFM, Mezzanotte W, Disse B, Finnigan H, Asijee G, et al. Eosinophilia, Frequent Exacerbations, and Steroid Response in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2017;196(9):1219–21.

Article  PubMed  Google Scholar 

Casanova C, Celli BR, de-Torres JP, Martínez-Gonzalez C, Cosio BG, Pinto-Plata V, de Lucas-Ramos P, Divo M, Fuster A, Peces-Barba G et al: Prevalence of persistent blood eosinophilia: relation to outcomes in patients with COPD. The European respiratory journal 2017, 50(5).

Chapman KR, Hurst JR, Frent SM, Larbig M, Fogel R, Guerin T, Banerji D, Patalano F, Goyal P, Pfister P, et al. Long-Term Triple Therapy De-escalation to Indacaterol/Glycopyrronium in Patients with Chronic Obstructive Pulmonary Disease (SUNSET): A Randomized, Double-Blind, Triple-Dummy Clinical Trial. Am J Respir Crit Care Med. 2018;198(3):329–39.

Article  PubMed  Google Scholar 

Vedel-Krogh S, Nielsen SF, Lange P, Vestbo J, Nordestgaard BG: Blood Eosinophils and Exacerbations in Chronic Obstructive Pulmonary Disease. The Copenhagen General Population Study. Am J Respir Crit Care Med 2016, 193(9):965–974.

Walters JA, Tan DJ, White CJ, Gibson PG, Wood-Baker R, Walters EH: Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2014(9):Cd001288.

Renkema TE, Schouten JP, Koëter GH, Postma DS. Effects of long-term treatment with corticosteroids in COPD. Chest. 1996;109(5):1156–62.

Article  PubMed  Google Scholar 

Rice KL, Rubins JB, Lebahn F, Parenti CM, Duane PG, Kuskowski M, Joseph AM, Niewoehner DE. Withdrawal of chronic systemic corticosteroids in patients with COPD: a randomized trial. Am J Respir Crit Care Med. 2000;162(1):174–8.

Article  PubMed  Google Scholar 

Dahl R, Chung KF, Buhl R, Magnussen H, Nonikov V, Jack D, Bleasdale P, Owen R, Higgins M, Kramer B. Efficacy of a new once-daily long-acting inhaled beta2-agonist indacaterol versus twice-daily formoterol in COPD. Thorax. 2010;65(6):473–9.

Article  PubMed  Google Scholar 

Melani AS. Long-acting muscarinic antagonists. Expert Rev Clin Pharmacol. 2015;8(4):479–501.

Article  PubMed  Google Scholar 

Appleton S, Jones T, Poole P, Pilotto L, Adams R, Lasserson TJ, Smith B, Muhammad J: Ipratropium bromide versus long-acting beta-2 agonists for stable chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2006, 2006(3):Cd006101.

Karner C, Chong J, Poole P: Tiotropium versus placebo for chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2014, 2014(7):Cd009285.

Kesten S, Casaburi R, Kukafka D, Cooper CB. Improvement in self-reported exercise participation with the combination of tiotropium and rehabilitative exercise training in COPD patients. Int J Chron Obstruct Pulmon Dis. 2008;3(1):127–36.

Article  PubMed  PubMed Central  Google Scholar 

Vestbo J, Anderson JA, Brook RD, Calverley PM, Celli BR, Crim C, Martinez F, Yates J, Newby DE. Fluticasone furoate and vilanterol and survival in chronic obstructive pulmonary disease with heightened cardiovascular risk (SUMMIT): a double-blind randomised controlled trial. Lancet. 2016;387(10030):1817–26.

Article  PubMed  Google Scholar 

Calverley PMA, Anderson JA, Brook RD, Crim C, Gallot N, Kilbride S, Martinez FJ, Yates J, Newby DE, Vestbo J, et al. Fluticasone Furoate, Vilanterol, and Lung Function Decline in Patients with Moderate Chronic Obstructive Pulmonary Disease and Heightened Cardiovascular Risk. Am J Respir Crit Care Med. 2018;197(1):47–55.

Article  PubMed  Google Scholar 

Han G, Ko SJ, Park JW, Kim J, Yeo I, Lee H, Kim SY, Lee H: Acupuncture for functional dyspepsia: study protocol for a two-center, randomized controlled trial. Current Controlled Trials in Cardiovascular Medicine 2014, 15.

Zhao L, Chen J, Li Y, Sun X, Chang X, Zheng H, Gong B, Huang Y, Yang M, Wu X, et al. The Long-term Effect of Acupuncture for Migraine Prophylaxis: A Randomized Clinical Trial. JAMA Intern Med. 2017;177(4):508–15.

Article  PubMed  Google Scholar 

Yang JW, Wang LQ, Zou X, Yan SY, Wang Y, Zhao JJ, Tu JF, Wang J, Shi GX, Hu H, et al. Effect of Acupuncture for Postprandial Distress Syndrome: A Randomized Clinical Trial. Ann Intern Med. 2020;172(12):777–85.

Article  PubMed  Google Scholar 

MacPherson H, Tilbrook H, Richmond S, Woodman J, Ballard K, Atkin K, Bland M, Eldred J, Essex H, Hewitt C, et al. Alexander Technique Lessons or Acupuncture Sessions for Persons With Chronic Neck Pain: A Randomized Trial. Ann Intern Med. 2015;163(9):653–62.

Article  PubMed  Google Scholar 

Brinkhaus B, Ortiz M, Witt CM, Roll S, Linde K, Pfab F, Niggemann B, Hummelsberger J, Treszl A, Ring J, et al. Acupuncture in patients with seasonal allergic rhinitis: a randomized trial. Ann Intern Med. 2013;158(4):225–34.

Article  PubMed  Google Scholar 

Maekura T, Miki K, Miki M, Kitada S, Maekura R. Clinical Effects Of Acupuncture On The Pathophysiological Mechanism Of Chronic Obstructive Pulmonary Disease During Exercise. Int J Chron Obstruct Pulmon Dis. 2019;14:2787–98.

Article  PubMed  PubMed Central  Google Scholar 

Lewith GT, Prescott P, Davis CL. Can a standardized acupuncture technique palliate disabling breathlessness: a single-blind, placebo-controlled crossover study. Chest. 2004;125(5):1783–90.

Article  PubMed  Google Scholar 

Jobst K, Chen JH, McPherson K, Arrowsmith J, Brown V, Efthimiou J, Fletcher HJ, Maciocia G, Mole P, Shifrin K, et al. Controlled trial of acupuncture for disabling breathlessness. Lancet. 1986;2(8521–22):1416–9.

Article  PubMed  Google Scholar 

Suzuki M, Muro S, Ando Y, Omori T, Shiota T, Endo K, Sato S, Aihara K, Matsumoto M, Suzuki S, et al. A randomized, placebo-controlled trial of acupuncture in patients with chronic obstructive pulmonary disease (COPD): the COPD-acupuncture trial (CAT). Arch Intern Med. 2012;172(11):878–86.

Article  PubMed  Google Scholar 

Schulz KF, Altman DG, Moher D. CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials. Ann Intern Med. 2010;152(11):726–32.

Article  PubMed  Google Scholar 

Macpherson H, Altman DG, Hammerschlag R, Li Y, Wu T, White A, Moher D, Group O: Revised STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA): extending the CONSORT statement. Acupuncture in medicine : journal of the British Medical Acupuncture Society 2010.

Zhouzhuo, Xuguixing, Huangliuyang, Hejiamei, Tianhao, liuyilin, Huangfengyuan, Zhuyijing, Huangying, Xiongchan et al: Exploration on the Clinical Points and Compatibility of Acupuncture-moxibustion Treatment of Chronic Obstructive Pulmonary Disease at Stable Period Based on Data Mining. World Science and Technology - Modernization of Traditional Chinese Medicine 2022, 24(11):208–215.

Zhou K, Fang J, Wang X, Yin W, Bing Z. Characterization of de qi with electroacupuncture at acupoints with different properties. J Altern Complement Med. 2011;17(11):1007.

Article  PubMed  PubMed Central  Google Scholar 

Zheng H, Gao T, Zheng QH, Lu LY, Hou TH, Zhang SS, Zhou SY, Hao XY, Wang L, Zhao L et al: Acupuncture for Patients With Chronic Tension-Type Headache: A Randomized Controlled Trial. Neurology 2022.

Huang K, Zhang P, Zhang Z, Youn JY, Wang C, Zhang H, Cai H. Traditional Chinese Medicine (TCM) in the treatment of COVID-19 and other viral infections: Efficacies and mechanisms. Pharmacol Ther. 2021;225:107843.

Article  PubMed  PubMed Central  Google Scholar 

Lyu M, Fan G, Xiao G, Wang T, Xu D, Gao J, Ge S, Li Q, Ma Y, Zhang H, et al. Traditional Chinese medicine in COVID-19. Acta pharmaceutica Sinica B. 2021;11(11):3337–63.

Article  PubMed  PubMed Central