Melendez-munoz R, Marchalik R, Jerussi T, Dimitrova D, Nussenblatt V, Beri A, et al. Cytomegalovirus infection incidence and risk factors across diverse hematopoietic cell transplantation platforms using a standardized monitoring and treatment approach: a comprehensive evaluation from a single institution. Biol Blood Marrow Transplant. 2019;25(3):577–86.

Article  PubMed  Google Scholar 

Manuel O, Husain S, Kumar D, Zayas C, Mawhorter S, Levi ME, et al. Assessment of cytomegalovirus-specific cell-mediated immunity for the prediction of cytomegalovirus disease in high-risk solid-organ transplant recipients: a multicenter cohort study. Clin Infect Dis. 2013;56(6):817–24.

Article  CAS  PubMed  Google Scholar 

Alonso-Álvarez S, Colado E, Moro-García MA, Alonso-Arias R. Cytomegalovirus in haematological tumours. Front Immunol. 2021;12:703256.

Article  PubMed  PubMed Central  Google Scholar 

Takizawa Y, Inokuma S, Tanaka Y, Saito K, Atsumi T, Hirakata M, et al. Clinical characteristics of cytomegalovirus infection in rheumatic diseases: multicentre survey in a large patient population. Rheumatology. 2008;47(9):1373–8.

Article  CAS  PubMed  Google Scholar 

Limaye AP, Kirby KA, Rubenfeld GD, Leisenring WM, Bulger EM, Neff MJ, et al. Cytomegalovirus reactivation in critically ill immunocompetent patients. JAMA. 2008;300(4):413–22.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chiche L, Forel JM, Roch A, Guervilly C, Pauly V, Allardet-Servent J, et al. Active cytomegalovirus infection is common in mechanically ventilated medical intensive care unit patients. Crit Care Med. 2009;37(6):1850–7.

Article  PubMed  Google Scholar 

Walton AH, Muenzer JT, Rasche D, Boomer JS, Sato B. Reactivation of multiple viruses in patients with sepsis. PLoS ONE. 2014;9(2): e98819.

Article  PubMed  PubMed Central  Google Scholar 

Li X, Huang Y, Xu Z, Zhang R, Liu X, Li Y, et al. Cytomegalovirus infection and outcome in immunocompetent patients in the intensive care unit: a systematic review and meta-analysis. BMC Infect Dis. 2018;18(1):1–10.

Article  Google Scholar 

Emery VC, Sabin CA, Cope AV, Gor D, Hassan-Walker AF, Griffiths PD. Application of viral-load kinetics to identify patients who develop cytomegalovirus disease after transplantation. Lancet. 2000;355(9220):2032–6.

Article  CAS  PubMed  Google Scholar 

Yong MK, Ananda-Rajah M, Cameron PU, Morrissey CO, Spencer A, Ritchie D, et al. Cytomegalovirus reactivation is associated with increased risk of late-onset invasive fungal disease after allogeneic hematopoietic stem cell transplantation: a multicenter study in the current era of viral load monitoring. Biol Blood Marrow Transplant. 2017;23(11):1961–7.

Article  PubMed  Google Scholar 

Garcia-Vidal C, Upton A, Kirby KA, Marr KA. Epidemiology of invasive mold infections in allogeneic stem cell transplant recipients: Biological risk factors for infection according to time after transplantation. Clin Infect Dis. 2008;47(8):1041–50.

Article  PubMed  Google Scholar 

Razonable RR, Humar A. Cytomegalovirus in solid organ transplant recipients-guidelines of the American society of transplantation infectious disease community of practice. Clin Transplant. 2019;33(9): e13512.

Article  PubMed  Google Scholar 

Ljungman P, de la Camara R, Robin C, Crocchiolo R, Einsele H, Hill JA, et al. Guidelines for the management of cytomegalovirus infection in patients with haematological malignancies and after stem cell transplantation from the 2017 European conference on Infections in Leukaemia (ECIL 7). Lancet Infect Dis. 2019;19(8):e260–72.

Article  PubMed  Google Scholar 

Vincent JL, Moreno R, Takala J, Willatts S, De Mendonça A, Bruining H, et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the working group on sepsis-related problems of the European society of intensive care medicine. Intens Care Med. 1996;22(7):707–10.

Article  CAS  Google Scholar 

Fryer JF, Heath AB, Kessler H, Rawlinson W, Boivin G, Preiksaitis J, et al. A collaborative study to establish the 1st WHO International Standard for human cytomegalovirus for nucleic acid amplification technology. Biologicals. 2016;44(4):242–51.

Article  CAS  PubMed  Google Scholar 

Chemaly RF, Yen-Lieberman B, Castilla EA, Reilly A, Arrigain S, et al. Correlation between viral loads of cytomegalovirus in blood and bronchoalveolar lavage specimens from lung transplant recipients determined by histology and immunohistochemistry. J Clin Microbiol. 2004;42(5):2168–72.

Article  PubMed  PubMed Central  Google Scholar 

Green ML, Leisenring W, Xie H, Mast C, Cui Y, Sandmaier BM, et al. CMV viral load and mortality after hematopoietic cell transplantation: a cohort study in the era of preemptive therapy. Lancet Haematol. 2016;176(5):139–48.

Google Scholar 

Manuel O, Kralidis G, Mueller NJ, Hirsch HH, Garzoni C, Van Delden C, et al. Impact of antiviral preventive strategies on the incidence and outcomes of cytomegalovirus disease in solid organ transplant recipients. Am J Transplant. 2013;13(9):2402–10.

Article  CAS  PubMed  Google Scholar 

Ong DSY, Spitoni C, Klein Klouwenberg PMC, Verduyn Lunel FM, Frencken JF, Schultz MJ, et al. Cytomegalovirus reactivation and mortality in patients with acute respiratory distress syndrome. Intensive Care Med. 2016;42(3):333–41.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Al-Omari A, Aljamaan F, Alhazzani W, Salih S, Arabi Y. Cytomegalovirus infection in immunocompetent critically ill adults: literature review. Ann Intensive Care. 2016;6(1):110.

Papazian L, Hraiech S, Lehingue S, Roch A, Chiche L, Wiramus S, et al. Cytomegalovirus reactivation in ICU patients. Intensive Care Med. 2016;42(1):28–37.

Article  CAS  PubMed  Google Scholar 

Westall GP, Michaelides A, Williams TJ, Snell GI, Kotsimbos TC. Human cytomegalovirus load in plasma and bronchoalveolar lavage fluid: a longitudinal study of lung transplant recipients. J Infect Dis. 2004;190(6):1076–83.

Article  PubMed  Google Scholar 

Suárez-Lledó M, Marcos MÁ, Cuatrecasas M, Bombi JA, Fernández-Avilés F, Magnano L, et al. Quantitative PCR is faster, more objective, and more reliable than immunohistochemistry for the diagnosis of cytomegalovirus gastrointestinal disease in allogeneic stem cell transplantation. Biol Blood Marrow Transplant. 2019;25(11):2281–6.

Article  PubMed  Google Scholar 

Lengliné E, Chevret S, Moreau AS, Pène F, Blot F, Bourhis JH, et al. Changes in intensive care for allogeneic hematopoietic stem cell transplant recipients. Bone Marrow Transplant. 2015;50(6):840–5.

Article  PubMed  Google Scholar 

Cantoni N, Hirsch HH, Khanna N, Gerull S, Buser A, Bucher C, et al. Evidence for a bidirectional relationship between cytomegalovirus replication and acute graft-versus-host disease. Biol Blood Marrow Transplant. 2010;16(9):1309–14.

Article  PubMed  Google Scholar 

Erard V, Guthrie KA, Seo S, Smith J, Huang M, Chien J, et al. Reduced mortality of cytomegalovirus pneumonia after hematopoietic cell transplantation due to antiviral therapy and changes in transplantation practices. Clin Infect Dis. 2015;61(1):31–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Santos CAQ, Brennan DC, Yusen RD, Olsen MA. Incidence, risk factors and outcomes of delayed-onset cytomegalovirus disease in a large retrospective cohort of lung transplant recipients. Transplantation. 2015;99(8):1658–66.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Meng XY, Fu HX, Zhu XL, Wang JZ, Liu X, Yan CH. Comparison of different cytomegalovirus diseases following haploidentical hematopoietic stem cell transplantation. Ann Hematol. 2020;99(11):2659–70.

Article  CAS  PubMed  Google Scholar 

Torres HA, Kontoyiannis DP, Bodey GP, Adachi JA, Luna MA, Tarrand JJ, et al. Gastrointestinal cytomegalovirus disease in patients with cancer: a two decade experience in a tertiary care cancer center. Eur J Cancer. 2005;41:2268–79.

Article  PubMed  Google Scholar 

Wetwittayakhlang P, Rujeerapaiboon N, Wetwittayakhlung P, Sripongpun P, Pruphetkaew N, Jandee S, et al. Clinical Features, endoscopic findings, and predictive factors for mortality in tissue-invasive gastrointestinal cytomegalovirus disease between immunocompetent and immunocompromised patients. Gastroenterol Res Pract. 2021;2021:8886525.

Article  PubMed  PubMed Central  Google Scholar 

Randolph-habecker J, Iwata M, Torok-storb B. Cytomegalovirus mediated myelosuppression. J Clin Virol. 2002;25:51–6.

Article  Google Scholar 

Boeckh M, Hoy C, Torok-Storb B. Occult cytomegalovirus infection of marrow stroma. Clin Infect Dis. 1998;26(1):209–10.